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Enantioselective N-Heterocyclic Carbene-Catalyzed Synthesis of Spirocyclic Oxindole-benzofuroazepinones 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 24, 页码: 15225-15235
作者:  Gao, Zhong-Hua;  Chen, Kun-Quan;  Zhang, Yan;  Kong, Ling-Mei;  Li, Yan;  Ye, Song
收藏  |  浏览/下载:249/0  |  提交时间:2019/03/18
Synthesis of Novel ent-Kaurane-Type Diterpenoid Derivatives Effective for Highly Aggressive Tumor Cells 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 9
作者:  Hu, Yu;  Li, Xiao-Nian;  Ma, Ze-Jin;  Puno, Pema-Tenzin;  Zhao, Yong;  Zhao, Yan;  Xiao, Ye-Zhi;  Zhang, Wei;  Liu, Jing-Ping
收藏  |  浏览/下载:164/0  |  提交时间:2019/03/18
ent-kaurane-type diterpenoid derivatives  antitumor  synthesis  
Spirocyclic polycyclic polyprenylated acylphloroglucinols from the ethyl acetate fraction of Hypericum henryi 期刊论文
TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 46, 页码: 4067-4072
作者:  Duan, Yao-Tao;  Zhang, Juan;  Lao, Yuan-Zhi;  Tan, Hong-Sheng;  Ye, Yan-Song;  Yang, Xing-Wei;  Xu, Hong-Xi;  Xu, Gang
浏览  |  Adobe PDF(895Kb)  |  收藏  |  浏览/下载:569/131  |  提交时间:2018/12/18
Polyprenylated Acylphloroglucinol  Hyperhenones G-m  Hypericum Henryi  Spirocyclic  Antitumor  
miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells 期刊论文
ANGIOGENESIS, 2018, 卷号: 21, 期号: 4, 页码: 849-860
作者:  Liang, Huichun;  Ge, Fei;  Xu, Yuhui;  Xiao, Ji;  Zhou, Zhongmei;  Liu, Rong;  Chen, Ceshi
收藏  |  浏览/下载:309/0  |  提交时间:2018/12/03
MiR-153  Angiopoietin 1  Endothelial cell  Tumor angiogenesis  Breast cancer  
Cytotoxic sesquiterpenoids from the leaves of Magnolia grandiflora 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 155, 页码: 182-190
作者:  Ding, Lin-Fen;  Su, Jia;  Pan, Zheng-Hong;  Zhang, Zhi-Jun;  Li, Xiao-Nian;  Song, Liu-Dong;  Wu, Xing-De;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1049Kb)  |  收藏  |  浏览/下载:593/149  |  提交时间:2018/11/12
Magnolia Grandiflora (Magnoliaceae)  Sesquiterpenoids  Cytotoxic Activity  Nf-kappa b Transcriptional Activity  
Aspergilates A to E, second metabolites from Aspergillus sp. isolated from Paeonia ostii 期刊论文
FITOTERAPIA, 2018, 卷号: 131, 页码: 204-208
作者:  Wang, Ju-Tao;  Zhang, Pei-Liang;  Liu, Jin-Song;  Wang, Guo-Kai;  Xu, Feng-Qing;  Chen, Lin;  Yu, Yang;  Wang, Gang
收藏  |  浏览/下载:134/0  |  提交时间:2019/03/18
Aspergillus sp.  Globoscinic acid derivatives  Cytotoxic activity  ECD calculation  
Pharmacophore modeling, molecular docking and molecular dynamics simulations toward identifying lead compounds for Chk1 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 卷号: 76, 页码: 53-60
作者:  Li, Yaping;  Peng, Jiale;  Zhou, Yeheng;  Li, Penghua;  Li, Yingying;  Liu, Xingyong;  Siddique, Abu Nasar;  Zhang, Li;  Zuo, Zhili
收藏  |  浏览/下载:149/0  |  提交时间:2018/11/12
Checkpoint kinase 1 inhibitor  Virtual screening  Pharmacophore modeling  Molecular docking  Molecular dynamics simulations  
Aurovertin B sensitizes colorectal cancer cells to NK cell recognition and lysis 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 503, 期号: 4, 页码: 3057-3063
作者:  Zhu, Huifang;  Wang, Fei;  Ju, Xiaoman;  Kong, Lingmei;  An, Tao;  Zhao, Zhangxun;  Liu, Jikai;  Li, Yan
收藏  |  浏览/下载:434/0  |  提交时间:2018/10/22
Aurovertin B  Cytotoxicity  Immunotherapy  NK cell  NKG2D ligands  
Discovery of novel wee1 inhibitors via structure-based virtual screening and biological evaluation 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2018, 卷号: 32, 期号: 9, 页码: 901-915
作者:  Li, Yaping;  Pu, Yinglan;  Liu, Hui;  Zhang, Li;  Liu, Xingyong;  Li, Yan;  Zuo, Zhili
收藏  |  浏览/下载:425/0  |  提交时间:2018/11/06
Wee1 inhibitors  Pharmacophore model  Molecular docking  Virtual screening  Molecular dynamics simulation  
Structurally diverse diterpenoids from Isodon pharicus 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2018, 卷号: 5, 期号: 15, 页码: 2379-2389
作者:  Hu, Zheng-Xi;  Xu, Hou-Chao;  Hu, Kun;  Liu, Miao;  Li, Xiao-Nian;  Li, Xing-Ren;  Du, Xue;  Zhang, Yong-Hui;  Puno, Pema-Tenzin;  Sun, Han-Dong
收藏  |  浏览/下载:346/0  |  提交时间:2018/09/17