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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
作者:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  收藏  |  浏览/下载:363/1  |  提交时间:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
为建设自主创新体系提供科技信息支撑 期刊论文
出版物, 3111, 期号: 0, 页码: 1—2
作者:  作者
Adobe PDF(328Kb)  |  收藏  |  浏览/下载:351/2  |  提交时间:2017/07/21
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
作者:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  收藏  |  浏览/下载:510/1  |  提交时间:2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
ANTITUMOR ACTIVITY OFGYTOGHALASIN D 期刊论文
JOURNAL OF ANTIBIOTICS, 2025, 页码: 722-723
作者:  Wen-Jie Guo;  Guan-Jun Tao;  Wen-Yi Tao;  Feng-Jie Cui;  Xian-Chun Jin;  Fang Bi;  Zheng-Hong Xu;  Zong-Hua Ao
Adobe PDF(241Kb)  |  收藏  |  浏览/下载:555/1  |  提交时间:2017/07/19
Small-Molecule Drugs in Immunotherapy 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359
作者:  Hao,Xuanrun;  Chen,Zhongliang;  Li,Haining;  Wei,Minqin;  Zuo,Zhili;  Su,Qing
浏览  |  Adobe PDF(29350Kb)  |  收藏  |  浏览/下载:117/19  |  提交时间:2024/07/25
Cancer immunotherapy  inhibitors  Pd-1/Pd-L1 inhibitor  IDO inhibitor  STING agonists  ROR gamma t agonists  TGF  beta inhibitors  INDOLEAMINE 2,3-DIOXYGENASE  SIGNALING INHIBITOR  DENDRITIC CELLS  GROWTH  TUMOR  PATHWAY  PEMBROLIZUMAB  RECEPTORS  DISCOVERY  VADIMEZAN  
Identification of undescribed key impurities of homoharringtonine bulk drug 期刊论文
NATURAL PRODUCT RESEARCH, 2023
作者:  Yu,Yang;  Wu,Jing;  Yue,Cong-Yong;  Zhang,Tao;  Cai,Xiang-Hai
浏览  |  Adobe PDF(1217Kb)  |  收藏  |  浏览/下载:174/49  |  提交时间:2024/07/25
Cephalotaxus fortunei  neohomoharringtonines A-C  homoharringtonine  structure identification  key impurities  
Steroidal alkaloids from the roots of Veratrum stenophyllum 期刊论文
FITOTERAPIA, 2023, 卷号: 166, 页码: 105464
作者:  Zhou,Zhong-Shun;  Liu,Yang -Yang;  Zhu,Yan-Yan;  Hu,Bin-Yuan;  He,Ying-Jie;  Luo,XiaoDong
浏览  |  Adobe PDF(1511Kb)  |  收藏  |  浏览/下载:169/54  |  提交时间:2024/07/25
Steroidal alkaloids  Veratrum stenophyllum  Cytotoxic bioactivity  ANTITUMOR-ACTIVITY  RHIZOMES  DNA  
Insights from the Endophytic Fungi in Amphisphaeria (Sordariomycetes): A. orixae sp. nov. from Orixa japonica and Its Secondary Metabolites 期刊论文
MICROORGANISMS, 2023, 卷号: 11, 期号: 5, 页码: 1268
作者:  Wang,Xiaojie;  Wanasinghe,Dhanushka N.;  Zhang,Jingyi;  Ma,Jian;  Zhou,Peifeng;  Zhang,Lijuan;  Lu,Yongzhong;  Zhang,Zhen
浏览  |  Adobe PDF(4333Kb)  |  收藏  |  浏览/下载:162/13  |  提交时间:2024/05/09
Amphisphaeriales  fungal taxonomy  hyphomycetes  isocoumarin  phylogeny  SP.-NOV.  ALKALOIDS  CONSTITUENTS  ALIGNMENT  CHOICE  
Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1219362
作者:  Guo,Xiuping;  Li,Rui;  Cui,Jinjin;  Hu,Chujuan;  Yu,Haoyang;  Ren,Ling;  Cheng,Yangyang;  Jiang,Jiandong;  Ding,Xiao;  Wang,Lulu
浏览  |  Adobe PDF(7660Kb)  |  收藏  |  浏览/下载:254/71  |  提交时间:2024/05/09
Erigeron Breviscapus Injection  Dengzhanxixin  Erigeron Breviscapus (Vant  ) Hand  -mazz  Colorectal Cancer  Necroptosis  Drug Resistance  Tumor-necrosis-factor  Colorectal-cancer  Natural Compounds  Scutellarin  Apoptosis  Proliferation  Macrophages  Migration  Invasion  Therapy  
Integrating morphology, molecular phylogeny and chemotaxonomy for the most effective authentication in Chinese Rubia with insights into origin and distribution of characteristic Rubiaceae-type cyclopeptides 期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2023, 卷号: 191, 期号: B, 页码: 115775
作者:  Zhang,Xuejia;  Yang,Li-E.;  Hu,Yanyun;  Wu,Xingdong;  Wang,Zhe;  Miao,Yuanyuan;  Sun,Hang;  Nie,Zelong;  Tan,Ninghua
浏览  |  Adobe PDF(10464Kb)  |  收藏  |  浏览/下载:152/49  |  提交时间:2024/07/30
Rubia  Molecular phylogeny  Chemotaxonomy  Authentication  Rubiaceae-type cyclopeptides  ANTITUMOR CYCLIC HEXAPEPTIDES  ENDOPHYTIC FUNGUS  SECONDARY METABOLITES  METABOLOMICS  EVOLUTION  DIVERSIFICATION  GENUS