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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download:15/1  |  Submit date:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
为建设自主创新体系提供科技信息支撑 期刊论文
出版物, 3111, 期号: 0, 页码: 1—2
Authors:  作者
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YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  Favorite  |  View/Download:178/1  |  Submit date:2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
ANTITUMOR ACTIVITY OFGYTOGHALASIN D 期刊论文
JOURNAL OF ANTIBIOTICS, 2025, 页码: 722-723
Authors:  Wen-Jie Guo;  Guan-Jun Tao;  Wen-Yi Tao;  Feng-Jie Cui;  Xian-Chun Jin;  Fang Bi;  Zheng-Hong Xu;  Zong-Hua Ao
Adobe PDF(241Kb)  |  Favorite  |  View/Download:298/1  |  Submit date:2017/07/19
C30 and C31 Triterpenoids and Triterpene Sugar Esters with Cytotoxic Activities from Edible Mushroom Fomitopsis pinicola (Sw. Ex Fr.) Krast 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 37, 页码: 10330-10341
Authors:  Peng, Xing-Rong;  Su, Hai-Guo;  Liu, Jun-Hong;  Huang, Yan-Jie;  Yang, Xin-Zhi;  Li, Zhong-Rong;  Zhou, Lin;  Qiu, Ming-Hua
Favorite  |  View/Download:14/0  |  Submit date:2019/11/07
Polyporaceae  Fomitopsis pinicola  C30 triterpenoids  C31 triterpenoids  cytotoxic activity  
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
Authors:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
Favorite  |  View/Download:7/0  |  Submit date:2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
Authors:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
Favorite  |  View/Download:13/0  |  Submit date:2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Synthesis and antitumor activity of aza-brazilan derivatives containing imidazolium salt pharmacophores 期刊论文
MEDCHEMCOMM, 2019, 卷号: 10, 期号: 6, 页码: 1027-1036
Authors:  Huang, Mingqin;  Duan, Shengzu;  Ma, Xueqiong;  Cai, Bicheng;  Wu, Dongmei;  Li, Yan;  Li, Liang;  Zhang, Hongbin;  Yang, Xiaodong
Favorite  |  View/Download:3/0  |  Submit date:2019/07/29
B591, a novel specific pan-PI3K inhibitor, preferentially targets cancer stem cells 期刊论文
ONCOGENE, 2019, 卷号: 38, 期号: 18, 页码: 3371-3386
Authors:  Zhou, Hongyu;  Yu, Chunlei;  Kong, Lingmei;  Xu, Xiaoliang;  Yan, Juming;  Li, Yingchao;  An, Tao;  Gong, Liang;  Gong, Yaxiao;  Zhu, Huifang;  Zhang, Hongbin;  Yang, Xiaodong;  Li, Yan
Favorite  |  View/Download:42/0  |  Submit date:2019/06/24
Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
Authors:  Deng, Guogang;  Zhou, Bei;  Wang, Jing;  Chen, Zhuo;  Gong, Liang;  Gong, Yaxiao;  Wu, Dongmei;  Li, Yan;  Zhang, Hongbin;  Yang, Xiaodong
Favorite  |  View/Download:14/0  |  Submit date:2019/07/29
Diosgenin  Cholesterol  Dehydroepiandrosterone  Imidazolium salt  Antitumor activities  Structure-activity relationships