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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
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Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download:200/1  |  Submit date:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines 期刊论文
出版物, 3111, 期号: 0, 页码: 1—28
Authors:  Ming-Ju Hsieh;  Chiao-Wen Lin;  Shun-Fa Yang;  Mu-Kuan Chen;  Hui-Ling Chiou
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Glabridin  Migration  Invasion  Matrix Metalloproteinase-9  Hepatoma  
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  Favorite  |  View/Download:328/1  |  Submit date:2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 210, 页码: 115491
Authors:  Gou,Leilei;  Yue,Grace Gar-Lee;  Lee,Julia Kin -Ming;  Puno,Pema Tenzin;  Lau,Clara Bik-San
View  |  Adobe PDF(16654Kb)  |  Favorite  |  View/Download:8/1  |  Submit date:2024/07/22
Breast cancer  Metastasis  Natural products  Eriocalyxin B  Cancer recurrence  Cancer stem cells  Gut microbiome  NF-KAPPA-B  STEM-CELLS  MOLECULAR-MECHANISMS  EXTRACELLULAR-MATRIX  TUMOR-GROWTH  APOPTOSIS  ANGIOGENESIS  PROGRESSION  CARCINOMA  LEUKEMIA  
青蒿素-4-芳氨基喹唑啉衍生物体外抗肿瘤机制研究 学位论文
, 2021
Authors:  范东梅
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青蒿素-4-芳氨基喹唑啉衍生物体外抗肿瘤机制研究 学位论文
, 2021
Authors:  范东梅
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Novel Signature Genes and Pathways Identified for Human Left Ventricle Cardiomyopathies Rise from different Etiologies 期刊论文
Journal of Biomedical Research and Reviews, 2021
Authors:  Jiao Tian;  Zheng Yuan Wu;  Ying Ying He;  Shubai Liu
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A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
Authors:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
View  |  Adobe PDF(8744Kb)  |  Favorite  |  View/Download:116/43  |  Submit date:2022/04/02
Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
Authors:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
View  |  Adobe PDF(523Kb)  |  Favorite  |  View/Download:87/23  |  Submit date:2022/04/02
Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID