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The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+ 期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
Authors:  M Song;  D Chen;  S P Yu
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Skf 96365  Trpc Channel  Glioblastoma  Calcium  na+/ca2+ Exchanger  Cell Cycle  Cell Death  
Pharmacophore modeling, molecular docking and molecular dynamics simulations toward identifying lead compounds for Chk1 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 卷号: 76, 页码: 53-60
Authors:  Li, Yaping;  Peng, Jiale;  Zhou, Yeheng;  Li, Penghua;  Li, Yingying;  Liu, Xingyong;  Siddique, Abu Nasar;  Zhang, Li;  Zuo, Zhili
Favorite  |  View/Download:23/0  |  Submit date:2018/11/12
Checkpoint kinase 1 inhibitor  Virtual screening  Pharmacophore modeling  Molecular docking  Molecular dynamics simulations  
Teuvincenone F Suppresses LPS-Induced Inflammation and NLRP3 Inflammasome Activation by Attenuating NEMO Ubiquitination 期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8, 页码: 565
Authors:  Zhao, Xibao;  Pu, Debing;  Zhao, Zizhao;  Zhu, Huihui;  Li, Hongrui;  Shen, Yaping;  Zhang, Xingjie;  Zhang, Ruihan;  Shen, Jianzhong;  Xiao, Weilie;  Chen, Weilin
View  |  Adobe PDF(3100Kb)  |  Favorite  |  View/Download:47/8  |  Submit date:2017/10/23
Teuvincenone f  Inflammation  Nlrp3 Inflammasome  Ubiquitination  Nemo  
USP7 作为结直肠肿瘤治疗靶点的研究 学位论文
: 中国科学院大学, 2017
Authors:  安涛
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USP7 inhibitor P5091 inhibits Wnt signaling and colorectal tumor growth 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2017, 卷号: 131, 期号: 1, 页码: 29-39
Authors:  An, Tao;  Gong, Yaxiao;  Li, Xue;  Kong, Lingmei;  Ma, Pengcheng;  Gong, Liang;  Zhu, Huifang;  Yu, Chunlei;  Liu, Jianmei;  Zhou, Hongyu;  Mao, Bingyu;  Li, Yan
View  |  Adobe PDF(3138Kb)  |  Favorite  |  View/Download:625/97  |  Submit date:2017/04/06
Usp7 Inhibitor  Wnt Signaling  Colorectal Cancer  
Quantitative proteomics analysis of Caenorhabditis elegans upon germ cell loss 期刊论文
JOURNAL OF PROTEOMICS, 2017, 卷号: 156, 期号: 1, 页码: 85-93
Authors:  Pu, Yuan-Zhu;  Wan, Qin-Li;  Ding, Ai-Jun;  Luo, Huai-Rong;  Wu, Gui-Sheng
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Caenorhabditis Elegans  Proteomics  Aging  Notch Receptor Glp-1  Reproduction  
Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 期号: 0, 页码: 42176
Authors:  Li, Mingyue;  Song, Li-Hua;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Zhao, Li-Mei;  Li, Lin;  Zhou, Xunian;  Tsui, Stephen Kwok-Wing;  Ng, Simon Siu-Man;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
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Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
Authors:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
View  |  Adobe PDF(3775Kb)  |  Favorite  |  View/Download:48/3  |  Submit date:2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling  
Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 2, 页码: 2681-2693
Authors:  Cheng, Xin;  Liu, Yong-Qiang;  Wang, Gui-Zhen;  Yang, Li-Na;  Lu, Yong-Zhi;  Li, Xin-Chun;  Zhou, Bo;  Qu, Li-Wei;  Wang, Xiao-Lu;  Cheng, Yong-Xian;  Liu, Jinsong;  Tao, Sheng-Ce;  Zhou, Guang-Biao
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Proteome Microarray  6-o-angeloylplenolin  Stat3 Inhibitor  Skp2  Lung Cancer  
The Therapeutic Effects of Longikaurin A, a Natural ent-Kauranoid, in Esophageal Squamous Cell Carcinoma Depend on ROS Accumulation and JNK/p38 MAPK Activation 期刊论文
Toxicology Letters, 2017, 卷号: 280, 页码: 106–115
Authors:  Yun Chea;  Jingnan Wang;  Zuyang Yuan;  Yuan Li;   Zhiliang Lu;  Zhirong Zhang;  Jinyao Zhang;  Jun Wan;  Handong Sun;  Zhaoli Chen;  Jianxin Pu;  Jie He
View  |  Adobe PDF(1858Kb)  |  Favorite  |  View/Download:42/7  |  Submit date:2017/11/20