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Effects of Low Nighttime Temperature on Fatty Acid Content in Developing Seeds from Brassica napus L. Based on RNA-Seq and Metabolome 期刊论文
PLANTS-BASEL, 2023, 卷号: 12, 期号: 2, 页码: 325
作者:  Mi,Chao;  Sun,Chao;  Yuan,Yuting;  Li,Fei;  Wang,Qian;  Zhu,Haiping;  Hua,Shuijin;  Lin,Liangbin
浏览  |  Adobe PDF(5597Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/09
Brassica napus L  seeds  nighttime temperature  fatty acid content  RNA-seq  metabolome  cis-acting element involved in low-temperature responsiveness  oleic acid  erucic acid  HB1  KCS  TRANSCRIPTION FACTOR  OIL  EXPRESSION  STORAGE  GENES  CANOLA  LEAFY-COTYLEDON1  BIOSYNTHESIS  ACCUMULATION  REVEALS  
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:  Zhao,Qi;  Dai,Man-Yun;  Huang,Ruo-Yue;  Duan,Jing-Yi;  Zhang,Ting;  Bao,Wei-Min;  Zhang,Jing-Yi;  Gui,Shao-Qiang;  Xia,Shu-Min;  Dai,Cong-Ting;  Tang,Ying-Mei;  Gonzalez,Frank J. J.;  Li,Fei
浏览  |  Adobe PDF(5393Kb)  |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/09
FATTY LIVER-DISEASE  INDUCED CHOLESTASIS  STELLATE CELLS  PROBIOTICS  PROTECTS  INFLAMMATION  APOPTOSIS  OBESITY  AXIS  
Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
作者:  Dai, Manyun;  Peng, Wan;  Zhang, Ting;  Zhao, Qi;  Ma, Xiaofang;  Cheng, Yan;  Wang, Chunyan;  Li, Fei
收藏  |  浏览/下载：241/0  |  提交时间：2022/07/15
Tripterygium wilfordii  Liver injury  PPAR alpha  IL6-STAT3  Metabolomics  
PXR mediates mifepristone-induced hepatomegaly in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
作者:  Yao,Xin-peng;  Jiao,Ting-ying;  Jiang,Yi-ming;  Fan,Shi-cheng;  Zhao,Ying-yuan;  Yang,Xiao;  Gao,Yue;  Li,Fei;  Zhou,Yan-ying;  Chen,Pan-pan;  Huang,Min;  Bi,Hui-chang
收藏  |  浏览/下载：74/0  |  提交时间：2022/04/02
mifepristone  hepatomegaly  pregnane X receptor (PXR)  yes-associated protein (YAP)  
Comparative Metabolomic Profiling of the Metabolic Differences of Delta 9-Tetrahydrocannabinol and Cannabidiol 期刊论文
MOLECULES, 2022, 卷号: 27, 期号: 21, 页码: 7573
作者:  Rao, Qianru;  Zhang, Ting;  Dai, Manyun;  Li, Bin;  Pu, Qianlun;  Zhao, Min;  Cheng, Yan;  Yan, Dongmei;  Zhao, Qi;  Wu, Zhanxuan E.;  Li, Fei
浏览  |  Adobe PDF(2786Kb)  |  收藏  |  浏览/下载：3/1  |  提交时间：2024/04/30
cannabis  Delta 9-tetrahydrocannabinol  cannabidiol  metabolomics  CANNABINOIDS  
Hepatic RACK1 deletion disturbs lipid and glucose homeostasis independently of insulin resistance 期刊论文
JOURNAL OF ENDOCRINOLOGY, 2022, 卷号: 254, 期号: 3, 页码: 151-165
作者:  Qin, Wanying;  Zhang, Ting;  Ge, Mingxia;  Zhou, Huimin;  Xu, Yuhui;  Mu, Rongfang;  Huang, Chaoguang;  Liu, Daowei;  Huang, Bangrui;  Wang, Qian;  Kong, Qinghua;  Kong, Qingpeng;  Li, Fei;  Xiong, Wenyong
Adobe PDF(9525Kb)  |  收藏  |  浏览/下载：6/3  |  提交时间：2024/04/30
RACK1  bile acid  glucose metabolism  insulin sensitivity  ENDOPLASMIC-RETICULUM STRESS  C-KINASE 1  HEPATOCELLULAR-CARCINOMA  STEROL 12-ALPHA-HYDROXYLASE  DOWN-REGULATION  ER STRESS  KAPPA-B  RECEPTOR  ACTIVATION  GROWTH  
Polyamine metabolism links gut microbiota and testicular dysfunction 期刊论文
MICROBIOME, 2021, 卷号: 9, 期号: 1, 页码: 224
作者:  Zhao,Qi;  Huang,Jian-Feng;  Cheng,Yan;  Dai,Man-Yun;  Zhu,Wei-Feng;  Yang,Xiu-Wei;  Gonzalez,Frank J.;  Li,Fei
收藏  |  浏览/下载：40/0  |  提交时间：2022/04/02
Testicular dysfunction  Gut microbiota  Polyamine metabolism  Metabolomics  SMALL-MOLECULE INHIBITOR  ORNITHINE-DECARBOXYLASE  TRIPTOLIDE  SPERMINE  ACTIVATION  DISRUPTION  MECHANISMS  EXPRESSION  APOPTOSIS  TRANSPORT  
Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 卷号: 44, 期号: 11, 页码: 2189-2205
作者:  Wang,Yi-Kun;  Zhou,Zi-Meng;  Dai,Man-Yun;  Ma,Xiao-Fang;  Xiao,Xue-Rong;  Zhang,Shou-Wen;  Liu,Hong-Ning;  Li,Fei
Adobe PDF(2083Kb)  |  收藏  |  浏览/下载：94/34  |  提交时间：2022/04/02
Fructus Aurantii  quality markers  metabolomics  serum pharmacochemistry  ultra high performance liquid chromatography  SERUM PHARMACOCHEMISTRY  RAT PLASMA  IDENTIFICATION  METABOLITES  IMMATURUS  COMPONENTS  EXTRACT  NEOHESPERIDIN  FINGERPRINT  NARINGIN  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
作者:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
浏览  |  Adobe PDF(2010Kb)  |  收藏  |  浏览/下载：88/13  |  提交时间：2022/04/02
Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
A strategy combining solid-phase extraction, multiple mass defect filtering and molecular networking for rapid structural classification and annotation of natural products: characterization of chemical diversity in Citrus aurantium as a case study 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 卷号: 413, 期号: 11, 页码: 2879-2891
作者:  Wang,Yi-Kun;  Xiao,Xue-Rong;  Zhou,Zi-Meng;  Xiao,Yao;  Zhu,Wei-Feng;  Liu,Hong-Ning;  Li,Fei
浏览  |  Adobe PDF(2565Kb)  |  收藏  |  浏览/下载：58/7  |  提交时间：2022/04/02
Solid-phase extraction  Multiple mass defect filtering  Molecular networking  Natural products annotation  Structure and substructure classifications