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Effect of CYP3A4 on liver injury induced by triptolide 期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 10
Authors:  Xiao, Xuerong;  Zhang, Ting;  Huang, Jianfeng;  Zhao, Qi;  Li, Fei
Favorite  |  View/Download:2/0  |  Submit date:2020/08/17
hepatotoxicity  metabolomics  triptolide  UPLC-QTOF-MS  
Gut microbiota protects from triptolide-induced hepatotoxicity: Key role of propionate and its downstream signalling events 期刊论文
PHARMACOLOGICAL RESEARCH, 2020, 卷号: 155, 页码: 10
Authors:  Huang, Jian-Feng;  Zhao, Qi;  Dai, Man-Yun;  Xiao, Xue-Rong;  Zhang, Ting;  Zhu, Wei-Feng;  Li, Fei
Favorite  |  View/Download:5/0  |  Submit date:2020/06/08
Triptolide  Hepatotoxicity  Gut microbiota  Propionate  Metabolomics  
Metabolic profiling of coumarins by the combination of UPLC-MS-based metabolomics and multiple mass defect filter 期刊论文
XENOBIOTICA, 2020, 页码: 14
Authors:  Xiao, Yao;  Wang, Yi-Kun;  Xiao, Xue-Rong;  Zhao, Qi;  Huang, Jian-Feng;  Zhu, Wei-Feng;  Li, Fei
Favorite  |  View/Download:6/0  |  Submit date:2020/05/27
Coumarins  metabolism  metabolomics  UPLC-MS  multiple mass defect filter  
Metabolic profiling of tyrosine kinase inhibitor nintedanib using metabolomics 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 180, 页码: 13
Authors:  Zhou, Zi-Meng;  Wang, Yi-Kun;  Yan, Dong-Mei;  Fang, Jian-He;  Xiao, Xue-Rong;  Zhang, Ting;  Cheng, Yan;  Xu, Kang-Ping;  Li, Fei
Favorite  |  View/Download:9/0  |  Submit date:2020/05/27
Nintedanib  Metabolism  Metabolomics  ADMET prediction  UPLC-ESI-QTOF-MS  
Comparative proteomic and transcriptomic analyses provide new insight into the formation of seed size in castor bean 期刊论文
BMC PLANT BIOLOGY, 2020, 卷号: 20, 期号: 1, 页码: 20
Authors:  Yu, Anmin;  Li, Fei;  Liu, Aizhong
Favorite  |  View/Download:29/0  |  Submit date:2020/03/24
Metabolomics reveals metabolite changes of patients with pulmonary arterial hypertension in China 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2020, 页码: 13
Authors:  Chen, Chenyang;  Luo, Fei;  Wu, Panyun;  Huang, Yiyuan;  Das, Avash;  Chen, Shenglan;  Chen, Jingyuan;  Hu, Xinqun;  Li, Fei;  Fang, Zhenfei;  Zhou, Shenhua
Favorite  |  View/Download:9/0  |  Submit date:2020/03/18
lipid metabolism  metabolomics  pulmonary arterial hypertension  
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
Authors:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(9057Kb)  |  Favorite  |  View/Download:19/6  |  Submit date:2020/03/26
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
Authors:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(1740Kb)  |  Favorite  |  View/Download:12/1  |  Submit date:2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Application of a high-resolution genetic map for chromosome-scale genome assembly and fine QTLs mapping of seed size and weight traits in castor bean 期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 11
Authors:  Yu, Anmin;  Li, Fei;  Xu, Wei;  Wang, Zaiqing;  Sun, Chao;  Han, Bing;  Wang, Yue;  Wang, Bo;  Cheng, Xiaomao;  Liu, Aizhong
View  |  Adobe PDF(4249Kb)  |  Favorite  |  View/Download:23/1  |  Submit date:2019/10/14
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(3136Kb)  |  Favorite  |  View/Download:27/8  |  Submit date:2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity