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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:  Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting;  Zhao,Qi;  Cheng,Yan;  Lin,Qiuxia;  Zhang,Binbin;  Liu,Aiming;  Rao,Qianru;  Huang,Jianfeng;  Zhao,Jinhua;  Gonzalez,Frank J.;  Li,Fei
浏览  |  Adobe PDF(17974Kb)  |  收藏  |  浏览/下载：209/20  |  提交时间：2024/07/17
Intestinal bleeding  Triptolide  Celastrol  Intestinal FXR  Tripterygium wilfordii  FARNESOID-X-RECEPTOR  BACTERIAL TRANSLOCATION  ACTIVATION  INFLAMMATION  DYSFUNCTION  TRIPTOLIDE  MICROBIOTA  PREVENTS  OBESITY  MICE  
Metabolomics Reveals Gut Microbiota Contribute to PPARα Deficiency-Induced Alcoholic Liver Injury 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023, 卷号: 22, 期号: 7, 页码: 2327-2338
作者:  Zhang,Ting;  Bao,Lijuan;  Zhao,Qi;  Wu,Zhanxuan E. E.;  Dai,Manyun;  Rao,Qianru;  Li,Fei
浏览  |  Adobe PDF(9616Kb)  |  收藏  |  浏览/下载：181/32  |  提交时间：2024/07/10
metabolomics  alcohol-induced liver injury  gut microbiota  PPAR & alpha  AROMATIC-AMINO-ACIDS  LIPID-METABOLISM  FED MICE  MODULATION  DISEASE  AXIS  OLEOYLETHANOLAMIDE  AGONIST  OBESITY  DEATH  
Metabolomics Reveals Gut Microbiota Contribute to PPAR & alpha; Deficiency-Induced Alcoholic Liver Injury 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023
作者:  Zhang,Ting;  Bao,Lijuan;  Zhao,Qi;  Wu,Zhanxuan E. E.;  Dai,Manyun;  Rao,Qianru;  Li,Fei
浏览  |  Adobe PDF(9616Kb)  |  收藏  |  浏览/下载：207/37  |  提交时间：2024/07/10
metabolomics  alcohol-induced liver injury  gut microbiota  PPAR & alpha  AROMATIC-AMINO-ACIDS  LIPID-METABOLISM  FED MICE  MODULATION  DISEASE  AXIS  OLEOYLETHANOLAMIDE  AGONIST  OBESITY  DEATH  
Tripterygium wilfordii protects against an animal model of autoimmune hepatitis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 309, 页码: 116365
作者:  Zhang,Ting;  Rao,Qianru;  Dai,Manyun;  Zhao,Qi;  Li,Fei
浏览  |  Adobe PDF(13950Kb)  |  收藏  |  浏览/下载：169/39  |  提交时间：2024/07/25
Tripterygium wilfordii tablets  Celastrol  Concanavalin A  Autophagy  TFEB  PXR  PREGNANE-X-RECEPTOR  CHOLESTATIC LIVER-INJURY  CELASTROL PROTECTS  AUTOPHAGY  OBESITY  DYSFUNCTION  DOMAIN  
Effects of Low Nighttime Temperature on Fatty Acid Content in Developing Seeds from Brassica napus L. Based on RNA-Seq and Metabolome 期刊论文
PLANTS-BASEL, 2023, 卷号: 12, 期号: 2, 页码: 325
作者:  Mi,Chao;  Sun,Chao;  Yuan,Yuting;  Li,Fei;  Wang,Qian;  Zhu,Haiping;  Hua,Shuijin;  Lin,Liangbin
浏览  |  Adobe PDF(5597Kb)  |  收藏  |  浏览/下载：149/48  |  提交时间：2024/05/09
Brassica napus L  seeds  nighttime temperature  fatty acid content  RNA-seq  metabolome  cis-acting element involved in low-temperature responsiveness  oleic acid  erucic acid  HB1  KCS  TRANSCRIPTION FACTOR  OIL  EXPRESSION  STORAGE  GENES  CANOLA  LEAFY-COTYLEDON1  BIOSYNTHESIS  ACCUMULATION  REVEALS  
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:  Zhao,Qi;  Dai,Man-Yun;  Huang,Ruo-Yue;  Duan,Jing-Yi;  Zhang,Ting;  Bao,Wei-Min;  Zhang,Jing-Yi;  Gui,Shao-Qiang;  Xia,Shu-Min;  Dai,Cong-Ting;  Tang,Ying-Mei;  Gonzalez,Frank J. J.;  Li,Fei
浏览  |  Adobe PDF(5393Kb)  |  收藏  |  浏览/下载：240/43  |  提交时间：2024/05/09
FATTY LIVER-DISEASE  INDUCED CHOLESTASIS  STELLATE CELLS  PROBIOTICS  PROTECTS  INFLAMMATION  APOPTOSIS  OBESITY  AXIS  
Comparative metabolism of THCA and THCV using UHPLC-Q-Exactive Orbitrap-MS 期刊论文
XENOBIOTICA, 2023, 卷号: 53, 期号: 1, 页码: 46-59
作者:  Rao,Qianru;  Zhang,Ting;  Pu,Qian-Lun;  Li,Bin;  Zhao,Qi;  Yan,Dong-Mei;  Wu,Zhanxuan E.;  Li,Fei
浏览  |  Adobe PDF(2972Kb)  |  收藏  |  浏览/下载：134/31  |  提交时间：2024/07/30
Delta(9)-tetrahydrocannabinolic acid  delta(9)-tetrahydrocannabivarin  tetrahydrocannabinol  comparative metabolism  UHPLC-Q-Exactive MS  OXIDATIVE STRESS  CANNABINOIDS  PHARMACOLOGY  ACID  CANNABIDIOL  PENETRATION  
Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
作者:  Dai, Manyun;  Peng, Wan;  Zhang, Ting;  Zhao, Qi;  Ma, Xiaofang;  Cheng, Yan;  Wang, Chunyan;  Li, Fei
收藏  |  浏览/下载：502/0  |  提交时间：2022/07/15
Tripterygium wilfordii  Liver injury  PPAR alpha  IL6-STAT3  Metabolomics  
Comparative Metabolomic Profiling of the Metabolic Differences of Delta 9-Tetrahydrocannabinol and Cannabidiol 期刊论文
MOLECULES, 2022, 卷号: 27, 期号: 21, 页码: 7573
作者:  Rao, Qianru;  Zhang, Ting;  Dai, Manyun;  Li, Bin;  Pu, Qianlun;  Zhao, Min;  Cheng, Yan;  Yan, Dongmei;  Zhao, Qi;  Wu, Zhanxuan E.;  Li, Fei
浏览  |  Adobe PDF(2786Kb)  |  收藏  |  浏览/下载：193/29  |  提交时间：2024/04/30
cannabis  Delta 9-tetrahydrocannabinol  cannabidiol  metabolomics  CANNABINOIDS  
Hepatic RACK1 deletion disturbs lipid and glucose homeostasis independently of insulin resistance 期刊论文
JOURNAL OF ENDOCRINOLOGY, 2022, 卷号: 254, 期号: 3, 页码: 151-165
作者:  Qin, Wanying;  Zhang, Ting;  Ge, Mingxia;  Zhou, Huimin;  Xu, Yuhui;  Mu, Rongfang;  Huang, Chaoguang;  Liu, Daowei;  Huang, Bangrui;  Wang, Qian;  Kong, Qinghua;  Kong, Qingpeng;  Li, Fei;  Xiong, Wenyong
浏览  |  Adobe PDF(9525Kb)  |  收藏  |  浏览/下载：215/27  |  提交时间：2024/04/30
RACK1  bile acid  glucose metabolism  insulin sensitivity  ENDOPLASMIC-RETICULUM STRESS  C-KINASE 1  HEPATOCELLULAR-CARCINOMA  STEROL 12-ALPHA-HYDROXYLASE  DOWN-REGULATION  ER STRESS  KAPPA-B  RECEPTOR  ACTIVATION  GROWTH