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Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft' 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105314
Authors:  Chen,Jing;  Yu,Yang;  Wu,Jing;  Bao,Mei-Fen;  Kongkiatpaiboon,Sumet;  Schinnerl,Johann;  Cai,Xiang-Hai
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Tabernaemontana divaricata 'Dwaft'  Monoterpenoid indole alkaloid  Aspidosperma-type trimmers  Aspidosperma-type dimers  Cytotoxicity  MONOTERPENOID INDOLE ALKALOIDS  BISINDOLE ALKALOIDS  DIVERSE SKELETONS  A-I  CONOPHYLLINE  
Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft' 期刊论文
BIOORGANIC CHEMISTRY, 2021
Authors:  Chen,Jing;  Yu,Yang;  Wu,Jing;  Bao,Mei-Fen;  Kongkiatpaiboon,Sumet;  Schinnerl,Johann;  Cai,Xiang-Hai
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Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1175-1184
Authors:  Chen,Duo-Zhi;  Fan,Shi-Rui;  Yang,Bi-Juan;  Yao,Huo-Chun;  Wang,Yi-Ting;  Cai,Jie-Yun;  Jing,Chen-Xu;  Pan,Zi-Hao;  Luo,Miao;  Yuze,Yan-Qiu;  Liu,Guang-Jin;  Hao,Xiao-Jiang
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PROTEIN  CORONAVIRUSES  SARS  PARTICLES  INSIGHTS  HSC70  
Synthesis and anti-fibrotic effects of santamarin derivatives as cytotoxic agents against hepatic stellate cell line LX2 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 127994
Authors:  Wang,Jin-Ping;  Li,Tian-Ze;  Huang,Xiao-Yan;  Geng,Chang-An;  Shen,Cheng;  Sun,Jin-Jin;  Xue,Dong;  Chen,Ji-Jun
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Santamarin derivatives  Anti-fibrotic effects  HSC-LX2  Extracellular matrix  NF-KAPPA-B  SESQUITERPENE LACTONES  LIVER FIBROSIS  STRUCTURE REQUIREMENT  BAY LEAF  ACTIVATION  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
Authors:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
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Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Multiple in vitro biological effects of phenolic compounds from Terminalia chebula var. tomentella 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 275, 页码: 114135
Authors:  Zhang,Xiao-Rui;  Qiao,Yi-Jun;  Zhu,Hong-Tao;  Kong,Qing-Hua;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
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Terminalia chebula var  tomentella  Combretaceae  Fructus Chebulae  Hydrolyzed tannins  Simple phenolic compounds  Anti-inflammation  Anti-diabetes  NITRIC-OXIDE  ANTIOXIDANT  TANNINS  CONSTITUENTS  VALIDATION  ALGORITHM  ESTERS  FRUITS  
Discovery of novel inhibitors against main protease (Mpro) of SARS-CoV-2 via virtual screening and biochemical evaluation 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104767
Authors:  Guo,Sheng;  Xie,Hang;  Lei,Yu;  Liu,Bin;  Zhang,Li;  Xu,Yechun;  Zuo,Zhili
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SARS-CoV-2  Main protease  Virtual screening  Biochemical evaluation  
Non-volatile acylphloroglucinol components from Eucalyptus robusta inhibit Zika virus by impairing RdRp activity of NS5 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105303
Authors:  Yao,Zhai-Wen;  Liu,Hui;  Zhou,Rui;  Feng,Mi-Yan;  Wang,Fang;  Qin,Xu-Jie;  Chen,Xiu-Xiu;  Zheng,Chang-Bo;  Luo,Rong-Hua;  Yang,Liu-Meng;  Cen,Shan;  Xiong,Si-Dong;  Liu,Hai-Yang;  Zheng,Yong-Tang
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Eucalyptus robusta  Acylphloroglucinol dimer  Eucalyprobusone G  Anti-ZIKV agent  NS5 RdRp  INFECTION  BINDING  GROWTH  
Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives 期刊论文
BIOMACROMOLECULES, 2021, 卷号: 22, 期号: 3, 页码: 1244-1255
Authors:  Yin,Ronghua;  Zhou,Lutan;  Gao,Na;  Lin,Lisha;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Zuo,Zhili;  Hu,Kaifeng;  Huang,Shengxiong;  Liu,Jikai;  Zhao,Jinhua
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FUCOSYLATED CHONDROITIN SULFATE  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  SEA-CUCUMBER  FUCOSE BRANCHES  BODY-WALL  INDEPENDENT INHIBITION  POLYSACCHARIDE ACCOUNT  FACTOR XASE  HEPARIN  
Synthesis and biological activity of new bisbenzofuran-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020
Authors:  Wang, Xue-Quan;  Ye, Ping-Ting;  Bai, Meng-Jiao;  Miu, Wei-Hang;  Yang, Zhi-Xin;  Duan, Su-Yue;  Li, Tian-Tian;  Li, Yan;  Yang, Xiao-Dong
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