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Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 106375
Authors:  Peng,Xingrong;  Luo,Rongcan;  Ran,Xiaoqian;  Guo,Yarong;  Yao,Yong-Gang;  Qiu,Minghua
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Ganoderma  Ganoderma applanatum  Triterpenoid  Autophagy  Tau pathology  Alzheimer?s disease  LANOSTANE-TYPE TRITERPENOIDS  ALZHEIMERS-DISEASE  FRUITING BODIES  NEURODEGENERATION  ACID  
Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel 期刊论文
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
Authors:  Hu,Guilin;  Dong,Ding;  Du,Shuzong;  Peng,Xingrong;  Wu,Mingkun;  Shi,Qiangqiang;  Hu,Kun;  Hong,Defu;  Wang,Xiaoyuan;  Zhou,Lin;  Nian,Yin;  Qiu,Minghua
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Coffea arabica L  Roasted coffee  Coffee diterpenoid  Cafestol  Kahweol  T-type Ca2+ channels  Ca(v)3.1 low voltage-gated Ca2+ channel  Ca(v)3.1 inhibitors  CALCIUM-CHANNELS  CAFESTOL  KAHWEOL  PHYSIOLOGY  ESTERS  NOMENCLATURE  PHARMACOLOGY  APOPTOSIS  FURANS  
Hypermonones A-I, New Polyprenylated Acylphloroglucinols from Hypericum monogynum with Multidrug Resistance Reversal Activity 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 9, 页码: 2422-2432
Authors:  Zeng,Yan-Rong;  Li,Ya-Nan;  Yang,Jue;  Yi,Ping;  Huang,Lei;  Huang,Lie-Jun;  Gu,Wei;  Hu,Zhan-Xing;  Li,Yan-Mei;  Yuan,Chun-Mao;  Hao,Xiao-Jiang
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Hypericum monogynum  Phytochemistry  Structure elucidation  Biological activity  Multidrug resistance reversal activity  P-GLYCOPROTEIN  MODULATORS  CANCER  
Monoterpenoid Indole Alkaloids with Promoting Neurite Growth from Tabernaemontana divaricata 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 5, 页码: 1085-1092
Authors:  Deng,Yan;  Yu,Yang;  Shi,Bao-Bao;  Bao,Mei-Fen;  Zhao,Si-Meng;  Cai,Xiang-Hai
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Monoterpenoid indole alkaloid  Taberdicatines A-G  Structure elucidation  Extraction and isolation  Promoting neurite growth  
FPR2-based anti-inflammatory and anti-lipogenesis activities of novel meroterpenoid dimers from Ganoderma 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105338
Authors:  Peng,Xing-Rong;  Wang,Qian;  Wang,Hui-Rong;  Hu,Kun;  Xiong,Wen-Yong;  Qiu,Ming-Hua
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Ganoderma applanatum  Meroterpenoid dimers  Molecular docking  Anti-lipogenesis  FPR2-based inflammation  INDUCED INSULIN-RESISTANCE  ADIPOCYTE DIFFERENTIATION  OBESITY  INFLAMMATION  DEFICIENCY  MACROPHAGES  ACTIVATION  EXPRESSION  LIGAND  MICE  
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
Authors:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
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Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA  
Chaetolactam A, an Azaphilone Derivative from the Endophytic Fungus Chaetomium sp. g1 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 1, 页码: 475-483
Authors:  Zu,Wen-Yu;  Tang,Jian-Wei;  Hu,Kun;  Zhou,Yuan-Fei;  Gou,Lei-Lei;  Su,Xiao-Zheng;  Lei,Xinxiang;  Sun,Han-Dong;  Puno,Pema-Tenzin
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MASS-SPECTROMETRY  A-D  CASPASE-3  H-1  
Phyllaciduloids E and F, two new cleistanthane diterpenoids from the leaves of Phyllanthus acidus 期刊论文
NATURAL PRODUCT RESEARCH, 2021
Authors:  Geng,Hui-Chun;  Zhu,Hong-Tao;  Yang,Wei-Nong;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
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Phyllanthus acidus  cleistanthane diterpenoids  quantum chemical calculations  cytotoxicity  
Oligosaccharides from fucosylated glycosaminoglycan prevent breast cancer metastasis in mice by inhibiting heparanase activity and angiogenesis 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 166, 页码: 105527
Authors:  Zhou,Lutan;  Yin,Ronghua;  Gao,Na;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Ren,Lin;  Yang,Lian;  Zuo,Zhili;  Zhang,Hongbin;  Zhao,Jinhua
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Oligosaccharides  Heparanase  Angiogenesis  Metastasis  FIBROBLAST-GROWTH-FACTOR  TUMOR-GROWTH  SULFATE PROTEOGLYCANS  MAMMALIAN HEPARANASE  COMBINATION  MECHANISMS  DISCOVERY  BINDING  TARGET  PI-88  
Neuroprotective schinortriterpenoids from Schisandra neglecta collected in Medog County, Tibet, China 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104785
Authors:  Wang,Bin;  Hu,Kun;  Li,Xiao-Nian;  Sun,Han-Dong;  Qin,Hong-Bo;  Puno,Pema-Tenzin
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Schisandra neglecta  16  17-secopreschisanartane-type  schinortriterpenoids  Schisdilactones K?U  Quantum chemical calculation  Neuroprotective activity  DIBENZOCYCLOOCTADIENE LIGNANS  NORTRITERPENOIDS  CHINENSIS  STEMS  7,8-SECOLIGNANS  TRITERPENOIDS