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Anti-inflammatory evaluation and structure-activity relationships of diterpenoids isolated from Euphorbia hylonoma 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 10
作者:  Wei, Wen-Jun;  Qi, Weiyan;  Gao, Xin-Mei;  Feng, Ke-Na;  Ma, Kai-Liang;  Li, Hang-Ying;  Li, Ya;  Gao, Kun
Adobe PDF(2502Kb)  |  收藏  |  浏览/下载：191/42  |  提交时间：2020/03/18
Euphorbia hylonoma  ent-Isopimarane  ent-Rosane  Anti-inflammatory  
Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
作者:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
Adobe PDF(1542Kb)  |  收藏  |  浏览/下载：279/74  |  提交时间：2020/03/18
delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：195/30  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Hybrid isoquinolines from Thalictrum foetidum: a new type of aporphine inhibiting Staphylococcus aureus by combined mechanisms 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 19, 页码: 3428-3434
作者:  Ding, Cai-Feng;  Zhang, Rong-Ping;  Yu, Hao-Fei;  Yang, Jing;  Qin, Xu-Jie;  Dai, Zhi;  Liu, Ya-Ping;  Lu, Qiu-Min;  Lai, Ren;  Luo, Xiao-Dong
浏览  |  Adobe PDF(2565Kb)  |  收藏  |  浏览/下载：195/31  |  提交时间：2019/11/07
Phlegmadine A: A Lycopodium Alkaloid with a Unique Cyclobutane Ring from Phlegmariurus phlegmaria 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 84, 期号: 17, 页码: 11301-11305
作者:  Zhang, Zhi-Jun;  Wang, Chen;  Wu, Xing-De;  Huang, Yan;  Zhou, Wen-Xia;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1540Kb)  |  收藏  |  浏览/下载：184/20  |  提交时间：2019/11/07
Anti-BACE1 and anti-AchE activities of undescribed spiro-dioxolane-containing meroterpenoids from the endophytic fungus Aspergillus terreus Thom 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 165, 页码: 8
作者:  Qi, Changxing;  Zhou, Qun;  Gao, Weixi;  Liu, Mengting;  Chen, Chunmei;  Li, Xiao-Nian;  Lai, Yongji;  Zhou, Yuan;  Li, Dongyan;  Hu, Zhengxi;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1128Kb)  |  收藏  |  浏览/下载：284/151  |  提交时间：2019/10/14
Aspergillus terreus Thom  endophytic fungus  3,5-Dimethylorsellinic acid-based meroterpenoid  Adducts  Alzheimer's disease  
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1740Kb)  |  收藏  |  浏览/下载：207/24  |  提交时间：2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Acute and subacute toxicity evaluation of ethanol extract from aerial parts of Epigynum auritum in mice 期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2019, 卷号: 131, 页码: 8
作者:  Yang, Meilian;  Wu, Zihuan;  Wang, Yudan;  Kai, Guoyin;  Njateng, Guy Sedar Singor;  Cai, Shengbao;  Cao, Jianxin;  Cheng, Guiguang
浏览  |  Adobe PDF(1779Kb)  |  收藏  |  浏览/下载：176/50  |  提交时间：2019/10/28
Epigynum auritum  Acute and subacute oral toxicities  Hematology  Histopathology  Serum biochemistry analysis  
New aporphine alkaloids with selective cytotoxicity against glioma stem cells from Thalictrum foetidum 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 9, 页码: 698-706
作者:  Ding Cai-Feng;  Dai Zhi;  Yu Hao-Fei;  Zhao Xu-Dong;  Luo Xiao-Dong
浏览  |  Adobe PDF(3366Kb)  |  收藏  |  浏览/下载：186/77  |  提交时间：2019/10/28
Thalictrum foetidum  Aporphine alkaloids  Selective cytotoxicity  Glioma stem cells  
Mangiterpenes A-C and 2 ',3 '-seco-manginoid C, four sesquiterpene/monoterpene-shikimate-conjugated spirocyclic meroterpenoids from Guignardia mangiferae 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 236-242
作者:  Chen, Keliang;  Chen, Chunmei;  Guo, Jieru;  Sun, Weiguang;  Liu, Junjun;  Yang, Jing;  Liu, Xiulan;  Wang, Jianping;  Luo, Zengwei;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1608Kb)  |  收藏  |  浏览/下载：183/37  |  提交时间：2019/09/10
Guignardia Mangiferae  Spirocyclic Meroterpenoids  Anti-inflammatory  Nuclear Factor-kappa b (Nf-kappa b)