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Ormosianines A-P, Structurally Diverse Quinolizidine Alkaloids with AChE Inhibitory Effects from Ormosia yunnanensis 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2023, 卷号: 86, 期号: 9, 页码: 2193-2205
Authors:  Jin,Qiong;  Qin,Xu-Jie;  Sun,Wen-Jie;  Ding,Xiao;  Zhao,Yun;  Wang,Chang-Bin;  Tao,Xing-Yu;  Luo,Xiao-Dong
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ACETYLCHOLINESTERASE  SEEDS  PLANTS  
Oligomeric phloroglucinols with hAChE inhibitory and antibacterial activities from tropic Rhodomyrtus tomentosa 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 106836
Authors:  Luo,E-E;  Liu,Si-Na;  Wang,Zhao-Jie;  Chen,Ling-Yun;  Liang,Cheng-Qin;  Yu,Mu-Yuan;  Qin,Xu-Jie
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Rhodomyrtus tomentosa  Oligomeric phloroglucinols  h AChE inhibitors  Molecular docking  Antibacterial effects  MYRTUCOMMULONE  DERIVATIVES  ACYLPHLOROGLUCINOLS  MYRTUCOMMUACETALONE  LEAVES  
Dimeric benzylisoquinoline alkaloids from Thalictrum delavayi and their biological activities 期刊论文
FITOTERAPIA, 2023, 卷号: 164, 页码: 105356
Authors:  Jin,Qiong;  Qin,Xu-Jie;  Dai,Zhi;  Zhao,Yun;  Zhu,Yan-Yan;  Chen,Shan-Shan;  Liu,Ya-Ping;  Luo,Xiao-Dong
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Thalictrum delavayi  Ranunculaceae  Bisbenzylisoquinoline alkaloids  Cytotoxicities  Immunosuppressive effects  CYCLOARTANE GLYCOSIDES  APORPHINE  LEAVES  PLANTS  
Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
Authors:  Yan,Ying;  Ran,Xiaoqian;  Wang,Dan;  Zhang,Xiong;  Peng,Mingyou;  Yan,Xiaoyan;  Tang,Lei;  Liang,Hong;  Qin,Xujie;  Di,Ying-Tong;  Luo,Rongcan;  Hao,Xiao-Jiang;  Yao,Yong-Gang
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UBIQUITIN-PROTEASOME SYSTEM  ALZHEIMERS-DISEASE  CONSTITUENTS  LIMONOIDS  TFEB  NEURODEGENERATION  
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
Authors:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
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PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE  
HRESIMS-guided isolation of aspidosperma-scandine type bisindole alkaloids from Melodinus cochinchinensis and their anti-inflammatory and cytotoxic activities 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 184, 页码: 112673
Authors:  Li,Fang-Ru;  Liu,Lu;  Liu,Ya-Ping;  Wang,Jin-Tang;  Yang,Mei-Lian;  Khan,Afsar;  Qin,Xu-Jie;  Wang,Yu-Dan;  Cheng,Gui-Guang
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Melodinus cochinchinensis (Lour.) Merr. (Apocynaceae)  melokhanines  Bisindole alkaloids  Anti-inflammatory  Cytotoxicity  MONOTERPENOID INDOLE ALKALOIDS  CHEMISTRY  FRUITS  
Paris Saponin VII Induces Apoptosis and Cell Cycle Arrest in Erythroleukemia Cells by a Mitochondrial Membrane Signaling Pathway 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 4, 页码: 498-507
Authors:  Lin,Xin;  Gajendran,Babu;  Varier,Krishnapriya M.;  Liu,Wuling;  Song,Jingrui;  Rao,Qing;  Wang,Chunlin;  Qiu,Jianfei;  Ni,Wei;  Qin,XuJie;  Wen,Min;  Liu,Haiyang;  Li,Yanmei
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Leukemia  Paris Saponin VII  HEL  cell cycle  apoptosis  membrane signaling pathway  
New diterpenoids from the rhizomes of Hedychium forrestii 期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 15, 页码: 2463-2469
Authors:  Wang,Wen-Hui;  Gao,Jie-Jie;  Zuo,Xiao-Fei;  Qin,Xu-Jie;  Liu,Hai-Yang;  Zhao,Qing
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Hedychium forrestii  hexanorditerpenoid  hedychins C and D  cytotoxicity  LABDANE-TYPE DITERPENOIDS  CONSTITUENTS  CYTOTOXICITY  CORONARIUM  YUNNANENSE  
Acylphloroglucinols with acetylcholinesterase inhibitory effects from the fruits of Eucalyptus robusta (vol 103, 104127, 2020) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104579
Authors:  Liu,Hui;  He,Xiao-Zhi;  Feng,Mi-Yan;  Zeng,Yuan;  Rauwolf,Tyler J.;  Shao,Li-Dong;  Ni,Wei;  Yan,Hui;  Porco,John A.,Jr.;  Hao,Xiao-Jiang;  Qin,Xu-Jie;  Liu,Hai-Yang
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A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
Authors:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
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Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES