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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download:15/1  |  Submit date:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
PRIMER EXTENSION ENRICHMENTREACTION (PEER) AND OTHER METHODSFOR DIFFERENCE SCREENING 期刊论文
Nucleic Acids Hybridization, 3111, 页码: 125-165
Authors:  Qi Jun ZHANG;  Hui DOU;  Qun Xiong ZHENG;  Chang Xin ZHOU;  Zhao Jun XU;  Hua PENG;  Yu ZHAO
Adobe PDF(1298Kb)  |  Favorite  |  View/Download:37/2  |  Submit date:2017/07/19
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
Authors:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
Adobe PDF(1611Kb)  |  Favorite  |  View/Download:15/1  |  Submit date:2017/07/24
Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity 期刊论文
BMC Cancer, 2019, 卷号: 19, 期号: 1
Authors:  Wang,Ning;  Fan,Yanhua;  Yuan,Chun-Mao;  Song,Jialei;  Yao,Yao;  Liu,Wuling;  Gajendran,Babu;  Zacksenhaus,Eldad;  Li,Yanmei;  Liu,Jielin;  Hao,Xiao Jiang;  Ben-David,Yaacov
Favorite  |  View/Download:10/0  |  Submit date:2019/08/13
Cancer  Leukemia  Chinese medicinal plant  Melia azedarach  Drug screen  ERK1/2 agonists  Differentiation  Apoptosis  
Sphingofungins G and H: new five-membered lactones from Aspergillus penicilliodes Speg. 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 9, 页码: 1284-1291
Authors:  Zhang, Han;  Zhu, Hong-Tao;  Wang, Dong;  Yang, Chong-Ren;  Zhang, Ying-Jun
Favorite  |  View/Download:13/0  |  Submit date:2019/07/29
Aspergillus penicilliodes Speg  sphingofungins G and H  cytotoxicity  
Highly functionalized cyclohexanone-monocyclic polyprenylated acylphloroglucinols from Hypericum perforatum induce leukemia cell apoptosis 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 6, 页码: 817-824
Authors:  Guo, Yi;  Tong, Qingyi;  Zhang, Na;  Duan, Xueyan;  Cao, Yunfang;  Zhu, Hucheng;  Xie, Shuangshuang;  Yang, Jing;  Zhang, Jinwen;  Liu, Yanfei;  Xue, Yongbo;  Zhang, Yonghui
Favorite  |  View/Download:8/0  |  Submit date:2019/07/29
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
Authors:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
Favorite  |  View/Download:112/0  |  Submit date:2019/04/15
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
Authors:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
View  |  Adobe PDF(500Kb)  |  Favorite  |  View/Download:178/67  |  Submit date:2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
Authors:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
Favorite  |  View/Download:88/0  |  Submit date:2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Seeing the light: Shifting from wild rhizomes to extraction of active ingredients from above-ground parts of Paris polyphylla var. yunnanensis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 224, 期号: 1, 页码: 134-139
Authors:  Qin, Xu-Jie;  Ni, Wei;  Chen, Chang-Xiang;  Liu, Hai-Yang
View  |  Adobe PDF(944Kb)  |  Favorite  |  View/Download:65/12  |  Submit date:2018/09/27
Paris Polyphylla Var. Yunnanensis  Rhizoma Paridis  Steroidal Saponins  Sustainable Utilization