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Anticarin-beta shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2268-2279
作者:  Wang, Gan;  Zhang, Min;  Meng, Ping;  Long, Chengbo;  Luo, Xiaodong;  Yang, Xingwei;  Wang, Yunfei;  Zhang, Zhiye;  Mwangi, James;  Kamau, Peter Muiruri;  Dai, Zhi;  Ke, Zunfu;  Zhang, Yi;  Chen, Wenlin;  Zhao, Xudong;  Ge, Fei;  Lv, Qiumin;  Rong, Mingqiang;  Li, Dongsheng;  Jin, Yang;  Sheng, Xia;  Lai, Ren
浏览  |  Adobe PDF(4759Kb)  |  收藏  |  浏览/下载：36/6  |  提交时间：2024/04/30
Proteostasis  CCT  TRiC  Osteosarcoma  STAT3  Anticarin-beta  PDX model  CYTOSOLIC CHAPERONIN  CANCER-CELLS  COMPLEX  EXPRESSION  SURVIVAL  PROTEIN  TUBULIN  GROWTH  
Bioactivity Ingredients of Chaenomeles speciosa against Microbes: Characterization by LC-MS and Activity Evaluation 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 16, 页码: 4686-4696
作者:  Wang,Zhao-Jie;  Jin,Dan-Ni;  Zhou,Ying;  Sang,Xu-Yan;  Zhu,Yan-Yan;  He,Ying-Jie;  Xie,Tian-Zhen;  Dai,Zhi;  Zhao,Yun-Li;  Luo,Xiao-Dong
收藏  |  浏览/下载：92/0  |  提交时间：2022/04/02
antimicrobial  Chaenomeles speciosa  LC-MS  metabolomics  LUNG INFLAMMATION  ANTIOXIDANT  FRUITS  POLYSACCHARIDE  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
作者:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2120Kb)  |  收藏  |  浏览/下载：203/47  |  提交时间：2022/04/02
Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2630Kb)  |  收藏  |  浏览/下载：165/85  |  提交时间：2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Phenolic Amides with Immunomodulatory Activity from the Nonpolysaccharide Fraction of Lycium barbarum Fruits 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
作者:  Zhu, Pei-Feng;  Zhao, Yun-Li;  Dai, Zhi;  Qin, Xu-Jie;  Yuan, Hai-Lian;  Jin, Qiong;  Wang, Yi-Fen;  Liu, Ya-Ping;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1621Kb)  |  收藏  |  浏览/下载：212/80  |  提交时间：2021/01/05
Anti-Inflammatory Indole Alkaloids from the Stems of Kopsia officinalis 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020
作者:  Xie Tian-Zhen;  Zhao Yun-Li;  Ma Wei-Guang;  Wang Yi-Fen;  Yu Hao-Fei;  Wang Bei;  Wei Xin;  Huang Zhi-Pu;  Zhu Pei-Feng;  Liu Ya-Ping;  Luo Xiao-Dong
浏览  |  Adobe PDF(871Kb)  |  收藏  |  浏览/下载：153/56  |  提交时间：2021/01/05
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：250/72  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Novel nor-monoterpenoid indole alkaloids inhibiting glioma stem cells from fruits of Alstonia scholaris 期刊论文
PHYTOMEDICINE, 2018, 卷号: 48, 页码: 170-178
作者:  Wang, Bei;  Dai, Zhi;  Yang, Xiong-Wu;  Liu, Ya-Ping;  Khan, Afsar;  Yang, Zi-Feng;  Huang, Wan-Yi;  Wang, Xin-Hua;  Zhao, Xu-Dong;  Luo, Xiao-Dong
收藏  |  浏览/下载：216/0  |  提交时间：2018/10/04
Glioma stem cells  Antitumor activity  Alstonia scholaris  Nor-monoterpenoid indole alkaloids  
Effects of indole alkaloids from leaf of &ITAlstonia scholaris&IT on post-infectious cough in mice 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 218, 页码: 69-75
作者:  Zhao, Yun-Li;  Yang, Zi-Feng;  Shang, Jian-Hua;  Huang, Wan-Yi;  Wang, Bei;  Wei, Xin;  Khan, Afsar;  Yuan, Zhi-Wei;  Liu, Ya-Ping;  Wang, Yi-Fen;  Wang, Xin-Hua;  Luo, Xiao-Dong
收藏  |  浏览/下载：204/0  |  提交时间：2018/05/08
Leaf Of Alstonia Scholaris  Indole Alkaloids  Scholaricine  19-epischolaricine  Vallesamine  Picrinine  Post-infectious Cough  
Unprecedented sugar bridged bisindoles selective inhibiting glioma stem cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 1776-1783
作者:  Wei, Xin;  Dai, Zhi;  Yang, Jing;  Khan, Afsar;  Yu, Hao-Fei;  Zhao, Yun-Li;  Wang, Yi-Fen;  Liu, Ya-Ping;  Yang, Zi-Feng;  Huang, Wan-Yi;  Wang, Xin-Hua;  Zhao, Xu-Dong;  Luo, Xiao-Dong
收藏  |  浏览/下载：144/0  |  提交时间：2018/05/08
Alstoniasidines a And b  Sugar Bridged Bisindole  Glioma Stem Cells  Alstonia Scholaris