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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：1/1  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
Steroidal alkaloid with unprecedented triheterocyclic architecture 期刊论文
CHEMICAL COMMUNICATIONS, 2023, 卷号: 59, 期号: 3, 页码: 326-329
作者:  Zhou,Zhong-Shun;  Zhao,Yun-Li;  Hu,Bin-Yuan;  Wang,Bei;  Liu,Ya-Ping;  Zhu,Yan-Yan;  He,Ying-Jie;  Wang,Zhao-Jie;  Dai,Zhi;  Zhao,Li-Xing;  Luo,Xiao-Dong
浏览  |  Adobe PDF(975Kb)  |  收藏  |  浏览/下载：8/1  |  提交时间：2024/07/22
MALIC-ACID  SKELETON  
Anticarin-beta shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2268-2279
作者:  Wang, Gan;  Zhang, Min;  Meng, Ping;  Long, Chengbo;  Luo, Xiaodong;  Yang, Xingwei;  Wang, Yunfei;  Zhang, Zhiye;  Mwangi, James;  Kamau, Peter Muiruri;  Dai, Zhi;  Ke, Zunfu;  Zhang, Yi;  Chen, Wenlin;  Zhao, Xudong;  Ge, Fei;  Lv, Qiumin;  Rong, Mingqiang;  Li, Dongsheng;  Jin, Yang;  Sheng, Xia;  Lai, Ren
浏览  |  Adobe PDF(4759Kb)  |  收藏  |  浏览/下载：42/9  |  提交时间：2024/04/30
Proteostasis  CCT  TRiC  Osteosarcoma  STAT3  Anticarin-beta  PDX model  CYTOSOLIC CHAPERONIN  CANCER-CELLS  COMPLEX  EXPRESSION  SURVIVAL  PROTEIN  TUBULIN  GROWTH  
Bioactivity Ingredients of Chaenomeles speciosa against Microbes: Characterization by LC-MS and Activity Evaluation 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 16, 页码: 4686-4696
作者:  Wang,Zhao-Jie;  Jin,Dan-Ni;  Zhou,Ying;  Sang,Xu-Yan;  Zhu,Yan-Yan;  He,Ying-Jie;  Xie,Tian-Zhen;  Dai,Zhi;  Zhao,Yun-Li;  Luo,Xiao-Dong
收藏  |  浏览/下载：93/0  |  提交时间：2022/04/02
antimicrobial  Chaenomeles speciosa  LC-MS  metabolomics  LUNG INFLAMMATION  ANTIOXIDANT  FRUITS  POLYSACCHARIDE  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
作者:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2120Kb)  |  收藏  |  浏览/下载：213/48  |  提交时间：2022/04/02
Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Furostanol Saponins from Asparagus cochinchinensis and Their Cytotoxicity. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 6, 页码: 651-658
作者:  Zhang,Ruo-Song;  Liu,Yang-Yang;  Zhu,Pei-Feng;  Jin,Qiong;  Dai,Zhi;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1291Kb)  |  收藏  |  浏览/下载：118/44  |  提交时间：2022/04/02
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
作者:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
浏览  |  Adobe PDF(2630Kb)  |  收藏  |  浏览/下载：168/86  |  提交时间：2022/04/02
Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Rapid and unambiguous assignment of proton-deficient N-acyl amidine indole alkaloid by a combination of calculation methods 期刊论文
TETRAHEDRON LETTERS, 2021, 卷号: 68, 页码: 152949
作者:  Ding,Cai-Feng;  Yu,Hao-Fei;  Shi,Xiao-Long;  Ge,Shi-Cheng;  Njateng,Guy S. S.;  Qin,Xu-Jie;  Dai,Zhi;  Zhang,Rong-Ping;  Zhang,Hong-Bin;  Luo,Xiao-Dong
浏览  |  Adobe PDF(1013Kb)  |  收藏  |  浏览/下载：126/58  |  提交时间：2022/04/02
N-acyl amidine  Voafriamidine  Calculation methods  Antimicrobial activity  ASSISTED STRUCTURE ELUCIDATION  APORPHINE  DERIVATIVES  C-13  TOOL  
Phenolic Amides with Immunomodulatory Activity from the Nonpolysaccharide Fraction of Lycium barbarum Fruits 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
作者:  Zhu, Pei-Feng;  Zhao, Yun-Li;  Dai, Zhi;  Qin, Xu-Jie;  Yuan, Hai-Lian;  Jin, Qiong;  Wang, Yi-Fen;  Liu, Ya-Ping;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1621Kb)  |  收藏  |  浏览/下载：216/82  |  提交时间：2021/01/05
Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii 期刊论文
FITOTERAPIA, 2020, 卷号: 140, 页码: 6
作者:  Jin, Qiong;  Wei, Xin;  Qin, Xu-Jie;  Gao, Fei;  Zhu, Pei-Feng;  Yuan, Hai-Lian;  Njateng, Guy Sedar Singor;  Dai, Zhi;  Liu, Ya-Ping;  Luo, Xiao-Dong
收藏  |  浏览/下载：129/0  |  提交时间：2020/03/24
seco-aporphine derivatives  Immunosuppressive bioactivity  Thalictrum wangii