Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii | |
Jin, Qiong1,2; Wei, Xin1,3; Qin, Xu-Jie1; Gao, Fei2; Zhu, Pei-Feng1; Yuan, Hai-Lian1,2; Njateng, Guy Sedar Singor1; Dai, Zhi1,2; Liu, Ya-Ping1; Luo, Xiao-Dong1,2 | |
通讯作者 | Luo, Xiao-Dong(xdluo@mail.kib.ac.cn) |
2020 | |
发表期刊 | FITOTERAPIA |
ISSN | 0367-326X |
卷号 | 140页码:6 |
摘要 | Thallactones A (1) and B (2), enantiomeric aporphine alkaloids with rare cleaved rings A and B, as well as thaliglucine N-oxide (3) and their biosynthetically related precursor, northalphenine (4), were isolated from the whole plant of Thalictrum wangii Their structures with absolute configurations were elucidated by spectral techniques and electronic circular dichroism (ECD). Moreover, compounds 1, 3, and northalphenine inhibited concanavalin A (Con A)-stimulated proliferation of mice splenocyte significantly in a dose-dependent manner. |
关键词 | seco-aporphine derivatives Immunosuppressive bioactivity Thalictrum wangii |
DOI | 10.1016/j.fitote.2019.104445 |
收录类别 | SCI ; SCI |
语种 | 英语 |
WOS记录号 | WOS:000509630100018 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/70835 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
通讯作者 | Luo, Xiao-Dong |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Yunnan Univ, Sch Chem Sci & Technol, Minist Educ & Yunnan Prov, Key Lab Med Chem Nat Resource, Kunming 650091, Yunnan, Peoples R China 3.Guizhou Univ Tradit Chinese Med, Guiyang 550025, Peoples R China |
推荐引用方式 GB/T 7714 | Jin, Qiong,Wei, Xin,Qin, Xu-Jie,et al. Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii[J]. FITOTERAPIA,2020,140:6. |
APA | Jin, Qiong.,Wei, Xin.,Qin, Xu-Jie.,Gao, Fei.,Zhu, Pei-Feng.,...&Luo, Xiao-Dong.(2020).Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii.FITOTERAPIA,140,6. |
MLA | Jin, Qiong,et al."Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii".FITOTERAPIA 140(2020):6. |
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