Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii

doi:10.1016/j.fitote.2019.104445

	Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii
	Jin, Qiong 1,2; Wei, Xin 1,3; Qin, Xu-Jie1 ; Gao, Fei 2; Zhu, Pei-Feng 1; Yuan, Hai-Lian 1,2; Njateng, Guy Sedar Singor 1; Dai, Zhi 1,2; Liu, Ya-Ping 1; Luo, Xiao-Dong1,2
Corresponding Author	Luo, Xiao-Dong(xdluo@mail.kib.ac.cn)
	2020
Source Publication	FITOTERAPIA
ISSN	0367-326X
Volume	140 Pages:6
Abstract	Thallactones A (1) and B (2), enantiomeric aporphine alkaloids with rare cleaved rings A and B, as well as thaliglucine N-oxide (3) and their biosynthetically related precursor, northalphenine (4), were isolated from the whole plant of Thalictrum wangii Their structures with absolute configurations were elucidated by spectral techniques and electronic circular dichroism (ECD). Moreover, compounds 1, 3, and northalphenine inhibited concanavalin A (Con A)-stimulated proliferation of mice splenocyte significantly in a dose-dependent manner.
Keyword	seco-aporphine derivatives Immunosuppressive bioactivity Thalictrum wangii
DOI	10.1016/j.fitote.2019.104445
Indexed By	SCI ; SCI
Language	英语
WOS ID	WOS:000509630100018
Citation statistics	Cited Times:6[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.kib.ac.cn/handle/151853/70835
Collection	植物化学与西部植物资源持续利用国家重点实验室
Corresponding Author	Luo, Xiao-Dong
Affiliation	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Yunnan Univ, Sch Chem Sci & Technol, Minist Educ & Yunnan Prov, Key Lab Med Chem Nat Resource, Kunming 650091, Yunnan, Peoples R China 3.Guizhou Univ Tradit Chinese Med, Guiyang 550025, Peoples R China
Recommended Citation GB/T 7714	Jin, Qiong,Wei, Xin,Qin, Xu-Jie,et al. Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii[J]. FITOTERAPIA,2020,140:6.
APA	Jin, Qiong.,Wei, Xin.,Qin, Xu-Jie.,Gao, Fei.,Zhu, Pei-Feng.,...&Luo, Xiao-Dong.(2020).Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii.FITOTERAPIA,140,6.
MLA	Jin, Qiong,et al."Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii".FITOTERAPIA 140(2020):6.

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