Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii
Jin, Qiong1,2; Wei, Xin1,3; Qin, Xu-Jie1; Gao, Fei2; Zhu, Pei-Feng1; Yuan, Hai-Lian1,2; Njateng, Guy Sedar Singor1; Dai, Zhi1,2; Liu, Ya-Ping1; Luo, Xiao-Dong1,2
Corresponding AuthorLuo, Xiao-Dong(xdluo@mail.kib.ac.cn)
2020
Source PublicationFITOTERAPIA
ISSN0367-326X
Volume140Pages:6
AbstractThallactones A (1) and B (2), enantiomeric aporphine alkaloids with rare cleaved rings A and B, as well as thaliglucine N-oxide (3) and their biosynthetically related precursor, northalphenine (4), were isolated from the whole plant of Thalictrum wangii Their structures with absolute configurations were elucidated by spectral techniques and electronic circular dichroism (ECD). Moreover, compounds 1, 3, and northalphenine inhibited concanavalin A (Con A)-stimulated proliferation of mice splenocyte significantly in a dose-dependent manner.
Keywordseco-aporphine derivatives Immunosuppressive bioactivity Thalictrum wangii
DOI10.1016/j.fitote.2019.104445
Indexed BySCI ; SCI
Language英语
WOS IDWOS:000509630100018
Citation statistics
Cited Times:3[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/70835
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorLuo, Xiao-Dong
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Yunnan Univ, Sch Chem Sci & Technol, Minist Educ & Yunnan Prov, Key Lab Med Chem Nat Resource, Kunming 650091, Yunnan, Peoples R China
3.Guizhou Univ Tradit Chinese Med, Guiyang 550025, Peoples R China
Recommended Citation
GB/T 7714
Jin, Qiong,Wei, Xin,Qin, Xu-Jie,et al. Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii[J]. FITOTERAPIA,2020,140:6.
APA Jin, Qiong.,Wei, Xin.,Qin, Xu-Jie.,Gao, Fei.,Zhu, Pei-Feng.,...&Luo, Xiao-Dong.(2020).Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii.FITOTERAPIA,140,6.
MLA Jin, Qiong,et al."Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii".FITOTERAPIA 140(2020):6.
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