Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii
Jin, Qiong1,2; Wei, Xin1,3; Qin, Xu-Jie1; Gao, Fei2; Zhu, Pei-Feng1; Yuan, Hai-Lian1,2; Njateng, Guy Sedar Singor1; Dai, Zhi1,2; Liu, Ya-Ping1; Luo, Xiao-Dong1,2
通讯作者Luo, Xiao-Dong(xdluo@mail.kib.ac.cn)
2020
发表期刊FITOTERAPIA
ISSN0367-326X
卷号140页码:6
摘要Thallactones A (1) and B (2), enantiomeric aporphine alkaloids with rare cleaved rings A and B, as well as thaliglucine N-oxide (3) and their biosynthetically related precursor, northalphenine (4), were isolated from the whole plant of Thalictrum wangii Their structures with absolute configurations were elucidated by spectral techniques and electronic circular dichroism (ECD). Moreover, compounds 1, 3, and northalphenine inhibited concanavalin A (Con A)-stimulated proliferation of mice splenocyte significantly in a dose-dependent manner.
关键词seco-aporphine derivatives Immunosuppressive bioactivity Thalictrum wangii
DOI10.1016/j.fitote.2019.104445
收录类别SCI ; SCI
语种英语
WOS记录号WOS:000509630100018
引用统计
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/70835
专题植物化学与西部植物资源持续利用国家重点实验室
通讯作者Luo, Xiao-Dong
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Yunnan Univ, Sch Chem Sci & Technol, Minist Educ & Yunnan Prov, Key Lab Med Chem Nat Resource, Kunming 650091, Yunnan, Peoples R China
3.Guizhou Univ Tradit Chinese Med, Guiyang 550025, Peoples R China
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Jin, Qiong,Wei, Xin,Qin, Xu-Jie,et al. Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii[J]. FITOTERAPIA,2020,140:6.
APA Jin, Qiong.,Wei, Xin.,Qin, Xu-Jie.,Gao, Fei.,Zhu, Pei-Feng.,...&Luo, Xiao-Dong.(2020).Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii.FITOTERAPIA,140,6.
MLA Jin, Qiong,et al."Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii".FITOTERAPIA 140(2020):6.
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