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Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
浏览  |  Adobe PDF(11543Kb)  |  收藏  |  浏览/下载：70/12  |  提交时间：2024/07/17
Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
RUNX1-Regulated Signaling Pathways in Ovarian Cancer 期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
作者:  Chen,Yuanzhi;  He,Yingying;  Liu,Shubai
浏览  |  Adobe PDF(1447Kb)  |  收藏  |  浏览/下载：89/14  |  提交时间：2024/05/09
Runt-related transcription factor 1 (RUNX1)  ovarian cancer  apoptosis  signaling pathways  clinical therapeutic target  GROWTH-FACTOR  TRANSCRIPTION FACTORS  STEM-CELLS  RUNX1  STAT3  FAMILY  ACTIVATION  APOPTOSIS  LEUKEMIA  SURVIVAL  
Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 9, 页码: 8113
作者:  Xu,Xinglian;  Deng,Lulu;  Tang,Yaling;  Li,Jiang;  Zhong,Ting;  Hao,Xiaojiang;  Fan,Yanhua;  Mu,Shuzhen
浏览  |  Adobe PDF(5829Kb)  |  收藏  |  浏览/下载：78/17  |  提交时间：2024/05/09
leukemia  sanguinarine  c-MET  MAPK  PI3K/mTOR  STAT3  MET  
Anticarin-beta shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2268-2279
作者:  Wang, Gan;  Zhang, Min;  Meng, Ping;  Long, Chengbo;  Luo, Xiaodong;  Yang, Xingwei;  Wang, Yunfei;  Zhang, Zhiye;  Mwangi, James;  Kamau, Peter Muiruri;  Dai, Zhi;  Ke, Zunfu;  Zhang, Yi;  Chen, Wenlin;  Zhao, Xudong;  Ge, Fei;  Lv, Qiumin;  Rong, Mingqiang;  Li, Dongsheng;  Jin, Yang;  Sheng, Xia;  Lai, Ren
浏览  |  Adobe PDF(4759Kb)  |  收藏  |  浏览/下载：104/19  |  提交时间：2024/04/30
Proteostasis  CCT  TRiC  Osteosarcoma  STAT3  Anticarin-beta  PDX model  CYTOSOLIC CHAPERONIN  CANCER-CELLS  COMPLEX  EXPRESSION  SURVIVAL  PROTEIN  TUBULIN  GROWTH  
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
作者:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
浏览  |  Adobe PDF(8744Kb)  |  收藏  |  浏览/下载：164/55  |  提交时间：2022/04/02
Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
Bioinformatics analysis of differentially expressed genes in hepatocellular carcinoma cells exposed to Swertiamarin 期刊论文
JOURNAL OF CANCER, 2019, 卷号: 10, 期号: 26, 页码: 6526-6534
作者:  Tang, Haoran;  Ke, Yang;  Ren, Zongfang;  Lei, Xuefen;  Xiao, Shufeng;  Bao, Tianhao;  Shi, Zhitian;  Zou, Renchao;  Wu, Tiangen;  Zhou, Jian;  Geng, Chang-An;  Wang, Lin;  Chen, Jijun
浏览  |  Adobe PDF(2228Kb)  |  收藏  |  浏览/下载：200/48  |  提交时间：2020/03/24
swertiamarin  microarray  HepG2 cells  hepatocellular cancer  Jun  Stat3  
Isoharringtonine inhibits breast cancer stem-like properties and STAT3 signaling 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 103, 页码: 435-442
作者:  Chen, Wei;  Wang, Hui;  Cheng, Mei;  Ni, Ling;  Zou, Li;  Yang, Qin;  Cai, Xianghai;  Jiao, Baowei
收藏  |  浏览/下载：400/0  |  提交时间：2018/07/16
Triple-negative Breast Cancer  Cancer Stem Cells  Isoharringtonine  Stat3  
Targeted Metabolomics Reveals a Protective Role for Basal PPAR alpha in Cholestasis Induced by alpha-Naphthylisothiocyanate 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 4, 页码: 1500-1508
作者:  Dai, Manyun;  Hua, Huiying;  Lin, Hante;  Xu, Gangming;  Hu, Xiaowei;  Li, Fei;  Gonzalez, Frank J.;  Liu, Aiming;  Yang, Julin
浏览  |  Adobe PDF(2087Kb)  |  收藏  |  浏览/下载：285/64  |  提交时间：2018/05/08
Ppar Alpha  Nf-kappa b  Stat3  Alpha-naphthylisothiocyanate  Cholestasis  
Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 189-199
作者:  Li, Mingyue;  Yue, Grace Gar-Lee;  Song, Li-Hua;  Huang, Mao-Bo;  Lee, Julia Kin-Ming;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
浏览  |  Adobe PDF(2333Kb)  |  收藏  |  浏览/下载：247/50  |  提交时间：2018/07/02
Bigelovin  Colorectal Cancer  Metastasis  Tumor Microenvironment  Ll6/stat3 Pathway  
Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 2, 页码: 2681-2693
作者:  Cheng, Xin;  Liu, Yong-Qiang;  Wang, Gui-Zhen;  Yang, Li-Na;  Lu, Yong-Zhi;  Li, Xin-Chun;  Zhou, Bo;  Qu, Li-Wei;  Wang, Xiao-Lu;  Cheng, Yong-Xian;  Liu, Jinsong;  Tao, Sheng-Ce;  Zhou, Guang-Biao
浏览  |  Adobe PDF(7649Kb)  |  收藏  |  浏览/下载：229/27  |  提交时间：2017/04/18
Proteome Microarray  6-o-angeloylplenolin  Stat3 Inhibitor  Skp2  Lung Cancer