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Metabolomics Reveals Gut Microbiota Contribute to PPARα Deficiency-Induced Alcoholic Liver Injury 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023, 卷号: 22, 期号: 7, 页码: 2327-2338
作者:  Zhang,Ting;  Bao,Lijuan;  Zhao,Qi;  Wu,Zhanxuan E. E.;  Dai,Manyun;  Rao,Qianru;  Li,Fei
浏览  |  Adobe PDF(9616Kb)  |  收藏  |  浏览/下载:48/11  |  提交时间:2024/07/10
metabolomics  alcohol-induced liver injury  gut microbiota  PPAR & alpha  AROMATIC-AMINO-ACIDS  LIPID-METABOLISM  FED MICE  MODULATION  DISEASE  AXIS  OLEOYLETHANOLAMIDE  AGONIST  OBESITY  DEATH  
Metabolomics Reveals Gut Microbiota Contribute to PPAR & alpha; Deficiency-Induced Alcoholic Liver Injury 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023
作者:  Zhang,Ting;  Bao,Lijuan;  Zhao,Qi;  Wu,Zhanxuan E. E.;  Dai,Manyun;  Rao,Qianru;  Li,Fei
浏览  |  Adobe PDF(9616Kb)  |  收藏  |  浏览/下载:55/15  |  提交时间:2024/07/10
metabolomics  alcohol-induced liver injury  gut microbiota  PPAR & alpha  AROMATIC-AMINO-ACIDS  LIPID-METABOLISM  FED MICE  MODULATION  DISEASE  AXIS  OLEOYLETHANOLAMIDE  AGONIST  OBESITY  DEATH  
Hepatic Stellate Celland Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis 期刊论文
ACS NANO, 2023, 卷号: 17, 期号: 23, 页码: 23608-23625
作者:  Niu,Xia;  Meng,Yanan;  Cui,Jinjin;  Li,Rui;  Ding,Xiao;  Niu,Bingyu;  Chang,Ge;  Xu,Ning;  Li,Guiling;  Wang,Yucheng;  Wang,Lulu
浏览  |  Adobe PDF(5563Kb)  |  收藏  |  浏览/下载:47/7  |  提交时间:2024/07/10
liver fibrosis  dihydrotanshinone I  hepaticstellate cells  vitamin A  cyclodextrin  liver microbiome  STRATEGY  THERAPY  TARGET  NANOPARTICLES  PATHWAY  
Tripterygium wilfordii protects against an animal model of autoimmune hepatitis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 309, 页码: 116365
作者:  Zhang,Ting;  Rao,Qianru;  Dai,Manyun;  Zhao,Qi;  Li,Fei
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Tripterygium wilfordii tablets  Celastrol  Concanavalin A  Autophagy  TFEB  PXR  PREGNANE-X-RECEPTOR  CHOLESTATIC LIVER-INJURY  CELASTROL PROTECTS  AUTOPHAGY  OBESITY  DYSFUNCTION  DOMAIN  
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:  Zhao,Qi;  Dai,Man-Yun;  Huang,Ruo-Yue;  Duan,Jing-Yi;  Zhang,Ting;  Bao,Wei-Min;  Zhang,Jing-Yi;  Gui,Shao-Qiang;  Xia,Shu-Min;  Dai,Cong-Ting;  Tang,Ying-Mei;  Gonzalez,Frank J. J.;  Li,Fei
浏览  |  Adobe PDF(5393Kb)  |  收藏  |  浏览/下载:87/15  |  提交时间:2024/05/09
FATTY LIVER-DISEASE  INDUCED CHOLESTASIS  STELLATE CELLS  PROBIOTICS  PROTECTS  INFLAMMATION  APOPTOSIS  OBESITY  AXIS  
Prebiotic-Based Nanoamorphous Atorvastatin Attenuates Nonalcoholic Fatty Liver Disease by Retrieving Gut and Liver Health 期刊论文
SMALL STRUCTURES, 2023, 页码: 2200312
作者:  Cui,Jin-Jin;  Li,Rui;  Ma,Xiao-Lei;  Yu,Hao-Yang;  Luo,Zhi-Gang;  Du,Peng;  Ren,Ling;  Ding,Xiao;  Guo,Xiu-Ping;  Zheng,Wen-Sheng;  Jiang,Jian-Dong;  Che,Yongsheng;  Wang,Lu-Lu
浏览  |  Adobe PDF(26415Kb)  |  收藏  |  浏览/下载:82/19  |  提交时间:2024/07/30
atorvastatin  gut flora  nanoamorphous  nonalcoholic fatty liver disease  prebiotics  SOLID DISPERSIONS  STATIN USE  EFFICACY  STEATOHEPATITIS  FORMULATION  SAFETY  ABSORPTION  ACTIVATION  MICROBIOTA  CIRRHOSIS  
Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
作者:  Dai, Manyun;  Peng, Wan;  Zhang, Ting;  Zhao, Qi;  Ma, Xiaofang;  Cheng, Yan;  Wang, Chunyan;  Li, Fei
收藏  |  浏览/下载:390/0  |  提交时间:2022/07/15
Tripterygium wilfordii  Liver injury  PPAR alpha  IL6-STAT3  Metabolomics  
雷公藤制剂对消化系统的毒性机理研究 学位论文
: 中国科学院大学, 2022
作者:  代曼云
Adobe PDF(10574Kb)  |  收藏  |  浏览/下载:18/0  |  提交时间:2024/05/14
代谢组学,雷公藤,药源性肝损伤,消化性溃疡,FXR,ET-1, 肠道血管屏障  Metabolomics, Tripterygium wilfordii, Drug-induced liver injury, peptic ulcer disease, FXR, ET-1, intestinal vascular barrier.  
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RAR alpha-PPAR gamma-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice 期刊论文
NUTRIENTS, 2022, 卷号: 14, 期号: 12, 页码: 2411
作者:  Zhao, Zhuohui;  Deng, Zhen-Tao;  Huang, Suling;  Ning, Mengmeng;  Feng, Ying;  Shen, Yu;  Zhao, Qin-Shi;  Leng, Ying
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Alisol B  non-alcoholic steatohepatitis  RAR alpha  CD36  FATTY LIVER  HEPATIC STEATOSIS  RECEPTOR  ORIENTALE  LIPOPROTEINS  23-ACETATE  AGONIST  CD36  
Toxicity and Antiulcer Properties of Ipomoea wightii (Wall.) Choisy Leaves: An In Vivo Approach Using Wistar Albino Rats 期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2022, 卷号: 2022, 页码: 4328571
作者:  Sathyanarayanan, Saikumar;  Sreeja, Puthanpura Sasidharan;  Arunachalam, Karuppusamy;  Parimelazhagan, Thangaraj
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GLUTATHIONE-REDUCTASE  MEDICINAL-PLANTS  METHANOL EXTRACT  GASTRIC-ULCER  GAERTN. ROXB.  ANTIOXIDANT  PALMITOYLETHANOLAMIDE  METABOLISM  LIVER