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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：193/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Racemic immunosuppressive seco-aporphine derivatives from Thalictrurn wangii 期刊论文
FITOTERAPIA, 2020, 卷号: 140, 页码: 6
作者:  Jin, Qiong;  Wei, Xin;  Qin, Xu-Jie;  Gao, Fei;  Zhu, Pei-Feng;  Yuan, Hai-Lian;  Njateng, Guy Sedar Singor;  Dai, Zhi;  Liu, Ya-Ping;  Luo, Xiao-Dong
收藏  |  浏览/下载：129/0  |  提交时间：2020/03/24
seco-aporphine derivatives  Immunosuppressive bioactivity  Thalictrum wangii  
Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
作者:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
Adobe PDF(4714Kb)  |  收藏  |  浏览/下载：349/46  |  提交时间：2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Anti-BACE1 and anti-AchE activities of undescribed spiro-dioxolane-containing meroterpenoids from the endophytic fungus Aspergillus terreus Thom 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 165, 页码: 8
作者:  Qi, Changxing;  Zhou, Qun;  Gao, Weixi;  Liu, Mengting;  Chen, Chunmei;  Li, Xiao-Nian;  Lai, Yongji;  Zhou, Yuan;  Li, Dongyan;  Hu, Zhengxi;  Zhu, Hucheng;  Zhang, Yonghui
Adobe PDF(1128Kb)  |  收藏  |  浏览/下载：299/156  |  提交时间：2019/10/14
Aspergillus terreus Thom  endophytic fungus  3,5-Dimethylorsellinic acid-based meroterpenoid  Adducts  Alzheimer's disease  
Rapid discovery and functional characterization of diterpene synthases from basidiomycete fungi by genome mining 期刊论文
FUNGAL GENETICS AND BIOLOGY, 2019, 卷号: 128, 页码: 36-42
作者:  Li, Xin-Lin;  Xu, Yu-Xing;  Li, Yuan;  Zhang, Rui;  Hu, Tian-Yuan;  Su, Ping;  Zhou, Man;  Tang, Ting;  Zeng, Ying;  Yang, Yan-Long;  Gao, Wei
Adobe PDF(1544Kb)  |  收藏  |  浏览/下载：258/44  |  提交时间：2019/07/29
Basidiomycete  Ditepene synthase  Genome mining  Cembrane diterpene  (-)-cyatha-3,12-diene  Ent-kauran-16 alpha-ol  
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
作者:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
Adobe PDF(1387Kb)  |  收藏  |  浏览/下载：276/63  |  提交时间：2019/07/29
podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 13
作者:  Guan, Ruowei;  Peng, Yuan;  Zhou, Lutan;  Zheng, Wenqi;  Liu, Xixi;  Wang, Pin;  Yuan, Qingxia;  Gao, Na;  Zhao, Longyan;  Zhao, Jinhua
Adobe PDF(2313Kb)  |  收藏  |  浏览/下载：179/7  |  提交时间：2019/06/24
Apostichopus japonicus  fucosylated glycosaminoglycan  oligosaccharide  unambiguous structure  anti-Fxase  
Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 8, 页码: 2319-2327
作者:  Xu, Yuhui;  Niu, Yanfen;  Gao, Yuan;  Wang, Fang;  Qin, Wanying;  Lu, Yanting;  Hu, Jing;  Peng, Li;  Liu, Jikai;  Xiong, Wenyong
Adobe PDF(4940Kb)  |  收藏  |  浏览/下载：375/61  |  提交时间：2017/10/23
Insulin-resistance  Tuberculata Beumee  Metabolic Syndrome  Srebp  Liver  Cholesterol  Constituents  Homeostasis  Inhibition  Receptors  
Withanolides from aerial parts of Nicandra physalodes 期刊论文
PHYTOCHEMISTRY, 2017, 卷号: 137, 页码: 148-155
作者:  Yu, Mu-Yuan;  Zhao, Gao-Ting;  Liu, Jie-Qing;  Khan, Afsar;  Peng, Xing-Rong;  Zhou, Lin;  Dong, Jin-Run;  Li, Hai-Zhou;  Qiu, Ming-Hua
Adobe PDF(577Kb)  |  收藏  |  浏览/下载：310/54  |  提交时间：2017/06/30
Nicandra Physalodes  Solanaceae  Withanolides  Cytotoxicity  
Novel immunosuppressive pregnane glycosides from the leaves of Epigynum auritum 期刊论文
FITOTERAPIA, 2017, 卷号: 118, 页码: 107-111
作者:  Gao, Fei;  Yao, Yuan-Cheng;  Cai, Sheng-Bao;  Zhao, Tian-Rui;  Yang, Xiao-Yan;  Fan, Jian;  Li, Xiao-Nian;  Cao, Jian-Xin;  Cheng, Gui-Guang
Adobe PDF(623Kb)  |  收藏  |  浏览/下载：247/91  |  提交时间：2017/06/30
Epigynum Auritum  Epigynosides E-g  Pregnane Glycosides  Immunosuppressive