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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
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Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
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Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic Streptomyces 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 2, 页码: 177-182
作者:  Zhang, Zhouxin;  Cao, Pei;  Shang, Ning-Ning;  Yang, Jing;  Wang, Li;  Yan, Yijun;  Huang, Sheng-Xiong
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Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
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Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Leucoflavonine, a new bioactive racemic flavoalkaloid from the leaves of Leucosceptrum canum 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 2, 页码: 442-446
作者:  Feng, Ling;  Zhang, Yu;  Liu, Yan-Chun;  Liu, Yan;  Luo, Shi-Hong;  Huang, Chun-Shuai;  Li, Sheng-Hong
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Leucosceptrum canum  Lamiaceae  Flavoalkaloid  Leucoflavonine  Biological activities  
Cytotoxic Effects of Compounds Isolated from Ricinodendron heudelotii 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 11
作者:  Yakubu, Omolara F.;  Adebayo, Abiodun H.;  Dokunmu, Titilope M.;  Zhang, Ying-Jun;  Iweala, Emeka E. J.
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anticancer  Ricinodendron heudelotii  chemoprevention  
Diversified abietane family diterpenoids from the leaves of Leucosceptrurn canum and their cytotoxic activity 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 157, 页码: 43-52
作者:  Guo, Kai;  Liu, Yan-Chun;  Liu, Yan;  Luo, Shi-Hong;  Li, Wen-Yuan;  Li, Xiao-Nian;  Li, Sheng-Hong
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Leucosceptrum canum  Lamiaceae  Diterpenoids  Abietane family  Cytotoxic activity  
Enantioselective N-Heterocyclic Carbene-Catalyzed Synthesis of Spirocyclic Oxindole-benzofuroazepinones 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 24, 页码: 15225-15235
作者:  Gao, Zhong-Hua;  Chen, Kun-Quan;  Zhang, Yan;  Kong, Ling-Mei;  Li, Yan;  Ye, Song
收藏  |  浏览/下载:249/0  |  提交时间:2019/03/18
Synthesis of Novel ent-Kaurane-Type Diterpenoid Derivatives Effective for Highly Aggressive Tumor Cells 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 9
作者:  Hu, Yu;  Li, Xiao-Nian;  Ma, Ze-Jin;  Puno, Pema-Tenzin;  Zhao, Yong;  Zhao, Yan;  Xiao, Ye-Zhi;  Zhang, Wei;  Liu, Jing-Ping
收藏  |  浏览/下载:164/0  |  提交时间:2019/03/18
ent-kaurane-type diterpenoid derivatives  antitumor  synthesis  
miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells 期刊论文
ANGIOGENESIS, 2018, 卷号: 21, 期号: 4, 页码: 849-860
作者:  Liang, Huichun;  Ge, Fei;  Xu, Yuhui;  Xiao, Ji;  Zhou, Zhongmei;  Liu, Rong;  Chen, Ceshi
收藏  |  浏览/下载:309/0  |  提交时间:2018/12/03
MiR-153  Angiopoietin 1  Endothelial cell  Tumor angiogenesis  Breast cancer