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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download:45/1  |  Submit date:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
Structural and mechanistic basis of penicillin-bindingprotein inhibition by lactivicins 期刊论文
NATURE CHEMICAL BIOLOGY, 3111, 期号: 0, 页码: 1—5
Authors:  Pauline Macheboeuf;  Delphine S Fischer;  Tom Brown Jr;  Astrid Zervosen;  Andre´Luxen;  Bernard Joris;  Andrea Dessen;  Christopher J Schofield
Adobe PDF(425Kb)  |  Favorite  |  View/Download:32/1  |  Submit date:2017/07/21
The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+ 期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
Authors:  M Song;  D Chen;  S P Yu
Adobe PDF(1390Kb)  |  Favorite  |  View/Download:39/1  |  Submit date:2017/07/24
Skf 96365  Trpc Channel  Glioblastoma  Calcium  na+/ca2+ Exchanger  Cell Cycle  Cell Death  
Discovery of isopenicin A, a meroterpenoid as a novel inhibitor of tubulin polymerization 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 卷号: 525, 期号: 2, 页码: 303-307
Authors:  Chen, Lin;  Fan, Dong-Mei;  Tang, Jian-Wei;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Puno, Pema-Tenzin;  Li, Yan
Favorite  |  View/Download:19/0  |  Submit date:2020/06/08
Isopenicin A  Meroterpenoid  Microtubule  Cancer  Endophytic fungus  
Synthesis and Cytotoxic Activity of Novel Hybrid Compounds between Piperonyl and Imidazolium Salts 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 3, 页码: 669-678
Authors:  Liu Zhengfen;  Zi Yujin;  Zhang Linlin;  Fang Yongsheng;  Shen Yanzhen;  Li Yan;  Yang Xiaodong;  Zhang Hongbin
Favorite  |  View/Download:11/0  |  Submit date:2020/06/15
piperonyl  imidazolium salts  molecular hybridization  structure-activity relationship  cytotoxic activity  
Buxus alkaloid compound destabilizes mutant p53 through inhibition of the HSF1 chaperone axis 期刊论文
PHYTOMEDICINE, 2020, 卷号: 68, 页码: 12
Authors:  Wang Yu-Ling;  Wu Wei;  Su Yong-Nan;  Ai Zhi-Peng;  Mou Han-Chuan;  Wan Luo-Sheng;  Luo Ying;  Qiu Ming-Hua;  Zhang Ji-Hong
Favorite  |  View/Download:29/0  |  Submit date:2020/05/27
Buxus alkaloid  Cancer  Ubiquitination  Mutant p53  HSF1  
Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 6
Authors:  Wang, Xue-Quan;  Chen, Xue-Bing;  Ye, Ping-Ting;  Yang, Zhi-Xin;  Bai, Meng-Jiao;  Duan, Su-Yue;  Li, Yan;  Yang, Xiao-Dong
Favorite  |  View/Download:15/0  |  Submit date:2020/03/18
3-Benzylcoumarin  Imidazolium salts  Biological evaluation  Cytotoxic activity  Structure-activity relationships  
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
Authors:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
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C-28 steroids from the fruiting bodies of Ganoderma resinaceum with potential anti-inflammatory activity 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 168, 页码: 8
Authors:  Shi, Qiangqiang;  Huang, Yanjie;  Su, Haiguo;  Gao, Ya;  Peng, Xingrong;  Zhou, Lin;  Li, Xiaonian;  Qiu, Minghua
View  |  Adobe PDF(824Kb)  |  Favorite  |  View/Download:30/3  |  Submit date:2020/03/26
Ganoderma resinaceum boud  Ganodermataceae  Ergostane-type  Steroids  Anti-inflammatory activity  
Pu-Erh Tea Relaxes the Thoracic Aorta of Rats by Reducing Intracellular Calcium 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 13
Authors:  Luo, Dan;  Chen, Xuejiao;  Zhu, Xu;  Liu, Shuang;  Li, Jie;  Xu, Jianping;  Zhao, Jinhua;  Ji, Xu
View  |  Adobe PDF(4082Kb)  |  Favorite  |  View/Download:62/2  |  Submit date:2020/03/18
endothelium-independent vasodilation  hypertension  pu-erh tea  tea components  theabrownins