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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
Authors:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
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Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
Authors:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Favorite  |  View/Download:105/0  |  Submit date:2018/07/16
Acetyl-macrocalin b  Reactive Oxygen Species  P38 Mapk  Apoptosis  Chk1  Chk2  G2  m Phase Arrest  Nsclc  
大萼香茶菜乙素二乙酰化物的药物新用途 专利
申请日期: 2017-10-16, 公开日期: 2018-02-02
Inventors:  赫捷;  普建新;  王婧男;  孙汉董;  孙楠;  吴海燕;  高亦博
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细锥香茶菜乙素在制备抑制食管鳞癌细胞增殖的产品中的应用 专利
申请日期: 2017-05-05, 公开日期: 2017-09-29
Inventors:  赫捷;  普建新;  陈照丽;  孙汉董;  王婧男;  吴海燕
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Natural Product Vibsanin A Induces Differentiation of Myeloid Leukemia Cells through PKC Activation 期刊论文
CANCER RESEARCH, 2016, 卷号: 76, 期号: 9, 页码: 2698-2709
Authors:  Yu, Zu-Yin;  Xiao, He;  Wang, Li-Mei;  Shen, Xing;  Jing, Yu;  Wang, Lin;  Sun, Wen-Feng;  Zhang, Yan-Feng;  Cui, Yu;  Shan, Ya-Jun;  Zhou, Wen-Bing;  Xing, Shuang;  Xiong, Guo-Lin;  Liu, Xiao-Lan;  Dong, Bo;  Feng, Jian-Nan;  Wang, Li-Sheng;  Luo, Qing-Liang;  Zhao, Qin-Shi;  Cong, Yu-Wen
View  |  Adobe PDF(1368Kb)  |  Favorite  |  View/Download:115/38  |  Submit date:2016/08/22
Pentagalloylglucose downregulates cofilin1 and inhibits HSV-1 infection 期刊论文
ANTIVIRAL RESEARCH, 2011, 卷号: 89, 期号: 1, 页码: 98-108
Authors:  Pei, Ying;  Xiang, Yang-Fei;  Chen, Jia-Nan;  Lu, Chun-Hua;  Hao, Jing;  Du, Qian;  Lai, Chi-choi;  Qu, Chang;  Li, Shen;  Ju, Huai-Qiang;  Ren, Zhe;  Liu, Qiu-Ying;  Xiong, Sheng;  Qian, Chui-Wen;  Zeng, Fan-Li;  Zhang, Pei-Zhuo;  Yang, Chong-Ren;  Zhang, Ying-Jun;  Xu, Jun;  Kitazato, Kaio;  Wang, Yi-Fei
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Herpes Simplex Virus Type 1  Pentagalloylglucose  Two-dimensional Gel Electrophoresis  Actin Cytoskeleton  Cofilin1  
Antiplaatelet and Anti-Inflammatory Constituents and New Oxygenated Xanthnes from Hypericum gemeniflorum 期刊论文
Planta medica, 2002, 卷号: 68, 期号: 1, 页码: 25-29
Authors:  Mei-Ing Chung;  Jing-Ru Weng;  Jih-Pyang Wang;  Che-Ming Teng;  Chun-Nan Lin
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Hypericum Geminiflorum  Clusiaceae  Pentaoxygenated Xanthone  Antiplatelet  Anti-inflammatory