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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载:269/60  |  提交时间:2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Li, Ning;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
收藏  |  浏览/下载:180/0  |  提交时间:2018/07/16
Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC  
大萼香茶菜乙素二乙酰化物的药物新用途 专利
申请日期: 2017-10-16, 公开日期: 2018-02-02
发明人:  赫捷;  普建新;  王婧男;  孙汉董;  孙楠;  吴海燕;  高亦博
Adobe PDF(3053Kb)  |  收藏  |  浏览/下载:132/0  |  提交时间:2018/05/10
长管香茶菜甲素在制备抑制食管鳞癌细胞增殖的产品中的应用 专利
公开日期: 2018-04-20
发明人:  赫捷;  普建新;  车云;  孙汉董;  孙楠;  高亦博
收藏  |  浏览/下载:65/0  |  提交时间:2018/10/24