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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 卷号: 44, 期号: 11, 页码: 2189-2205
Authors:
Wang,Yi-Kun
;
Zhou,Zi-Meng
;
Dai,Man-Yun
;
Ma,Xiao-Fang
;
Xiao,Xue-Rong
;
Zhang,Shou-Wen
;
Liu,Hong-Ning
;
Li,Fei
Adobe PDF(2083Kb)
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Submit date:2022/04/02
Fructus Aurantii
quality markers
metabolomics
serum pharmacochemistry
ultra high performance liquid chromatography
SERUM PHARMACOCHEMISTRY
RAT PLASMA
IDENTIFICATION
METABOLITES
IMMATURUS
COMPONENTS
EXTRACT
NEOHESPERIDIN
FINGERPRINT
NARINGIN
A strategy combining solid-phase extraction, multiple mass defect filtering and molecular networking for rapid structural classification and annotation of natural products: characterization of chemical diversity in Citrus aurantium as a case study
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 卷号: 413, 期号: 11, 页码: 2879-2891
Authors:
Wang,Yi-Kun
;
Xiao,Xue-Rong
;
Zhou,Zi-Meng
;
Xiao,Yao
;
Zhu,Wei-Feng
;
Liu,Hong-Ning
;
Li,Fei
Adobe PDF(2565Kb)
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Submit date:2022/04/02
Solid-phase extraction
Multiple mass defect filtering
Molecular networking
Natural products annotation
Structure and substructure classifications
Discovery of quality markers in Rubus Chingii Hu using UPLC-ESI-QTOF-MS
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 203, 页码: 114200
Authors:
Zhou,Zi-Meng
;
Yan,Dong-Mei
;
Wang,Yi-Kun
;
Zhang,Ting
;
Xiao,Xue-Rong
;
Dai,Man-Yun
;
Zhang,Shou-Wen
;
Liu,Hong-Ning
;
Li,Fei
Favorite
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View/Download:15/0
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Submit date:2022/04/02
Raspberry
Q-markers
Quality evaluation
UPLC-ESI-QTOF-MS
COMPONENTS
ACTIVATION
PATHWAY
FRUITS
Plastid phylogenomic insights into relationships of all flowering plant families
期刊论文
BMC BIOLOGY, 2021, 卷号: 19, 期号: 1, 页码: 232
Authors:
Li,Hong-Tao
;
Luo,Yang
;
Gan,Lu
;
Ma,Peng-Fei
;
Gao,Lian-Ming
;
Yang,Jun-Bo
;
Cai,Jie
;
Gitzendanner,Matthew A.
;
Fritsch,Peter W.
;
Zhang,Ting
;
Jin,Jian-Jun
;
Zeng,Chun-Xia
;
Wang,Hong
;
Yu,Wen-Bin
;
Zhang,Rong
;
van der Bank,Michelle
;
Olmstead,Richard G.
;
Hollingsworth,Peter M.
;
Chase,Mark W.
;
Soltis,Douglas E.
;
Soltis,Pamela S.
;
Yi,Ting-Shuang
;
Li,De-Zhu
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Submit date:2022/04/02
Mesangiospermae
Tree of life
Interfamilial relationships
Plastome
PPA II
MULTIPLE SEQUENCE ALIGNMENT
EARLY DIVERSIFICATION
CHLOROPLAST GENOME
SEED PLANTS
SCALE DATA
ANGIOSPERMS
GENES
PHYLOGENETICS
RBCL
RESOLVES
Metabolic profiling of tyrosine kinase inhibitor nintedanib using metabolomics
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020
Authors:
Zhou, Zi-Meng
;
Wang, Yi-Kun
;
Yan, Dong-Mei
;
Fang, Jian-He
;
Xiao, Xue-Rong
;
Zhang, Ting
;
Cheng, Yan
;
Xu, Kang-Ping
;
Li, Fei
Adobe PDF(4095Kb)
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Submit date:2021/01/05
Anti-Inflammatory Indole Alkaloids from the Stems of Kopsia officinalis
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020
Authors:
Xie Tian-Zhen
;
Zhao Yun-Li
;
Ma Wei-Guang
;
Wang Yi-Fen
;
Yu Hao-Fei
;
Wang Bei
;
Wei Xin
;
Huang Zhi-Pu
;
Zhu Pei-Feng
;
Liu Ya-Ping
;
Luo Xiao-Dong
Adobe PDF(871Kb)
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Submit date:2021/01/05
Metabolic profiling of coumarins by the combination of UPLC-MS-based metabolomics and multiple mass defect filter
期刊论文
XENOBIOTICA, 2020
Authors:
Xiao, Yao
;
Wang, Yi-Kun
;
Xiao, Xue-Rong
;
Zhao, Qi
;
Huang, Jian-Feng
;
Zhu, Wei-Feng
;
Li, Fei
Adobe PDF(1541Kb)
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Submit date:2021/01/05
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
Authors:
Yang, Xiao-Nan
;
Wang, Yi-Kun
;
Zhu, Xu
;
Xiao, Xue-Rong
;
Dai, Man-Yun
;
Zhang, Ting
;
Qu, Yan
;
Yang, Xiu-Wei
;
Qin, Hong-Bo
;
Gonzalez, Frank J.
;
Li, Fei
Adobe PDF(9057Kb)
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Submit date:2020/03/26
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
Authors:
Wang, Yi-Kun
;
Yang, Xiao-Nan
;
Zhu, Xu
;
Xiao, Xue-Rong
;
Yang, Xiu-Wei
;
Qin, Hong-Bo
;
Gonzalez, Frank J.
;
Li, Fei
Adobe PDF(3136Kb)
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Submit date:2019/09/10
elemicin
l'-hydroxyelemicin
metabolic activation
cytotoxicity
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice
期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
Authors:
Wang, Yi-Kun
;
Yang, Xiao-Nan
;
Liang, Wei-Qing
;
Xiao, Yao
;
Zhao, Qi
;
Xiao, Xue-Rong
;
Gonzalez, Frank J.
;
Li, Fei
Adobe PDF(1101Kb)
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Submit date:2019/07/29
Pazopanib
hepatotoxicity
metabolomics
oxidative stress
ultra-performance liquid chromatography-electrospray ion source-quadrupole
time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)