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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  Favorite  |  View/Download：110/1  |  Submit date：2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
Authors:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  Favorite  |  View/Download：172/1  |  Submit date：2017/07/24
Using Dali for Structural Comparison of Proteins 期刊论文
Current Protocols in Bioinformatics, 3111, 期号: 0, 页码: 1-24
Authors:  Zuo Z(作者)
Adobe PDF(1615Kb)  |  Favorite  |  View/Download：198/1  |  Submit date：2017/07/24
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
Authors:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
Favorite  |  View/Download：107/0  |  Submit date：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
Authors:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
View  |  Adobe PDF(500Kb)  |  Favorite  |  View/Download：206/83  |  Submit date：2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
EVOLUTION OF ANGIOSPERM POLLEN. 6. THE CELASTRALES, OXALIDALES, AND MALPIGHIALES (COM) GLADE AND ZYGOPHYLLALES 期刊论文
ANNALS OF THE MISSOURI BOTANICAL GARDEN, 2018, 卷号: 103, 期号: 3, 页码: 393-442
Authors:  Tao, Zhi-Bin;  Wortley, Alexandra H.;  Lu, Lu;  Li, De-Zhu;  Wang, Hong;  Blackmore, Stephen
View  |  Adobe PDF(4361Kb)  |  Favorite  |  View/Download：132/18  |  Submit date：2019/03/18
Celastrales  Character State Distribution  Correlated Evolution  Fabids  Malpighiales  Oxalidales  Pollen Morphology  Pollination Syndrome  Systematic Significance  Zygophyllales  
Synthesis of Fucosylated Chondroitin Sulfate Nonasaccharide as a Novel Anticoagulant Targeting Intrinsic Factor Xase Complex 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 39, 页码: 12880-12885
Authors:  Zhang, Xiao;  Liu, Huiying;  Lin, Lisha;  Yao, Wang;  Zhao, Jinhua;  Wu, Mingyi;  Li, Zhongjun
View  |  Adobe PDF(1568Kb)  |  Favorite  |  View/Download：99/14  |  Submit date：2018/10/22
Anticoagulants  Drug Discovery  Fucosylated Chondroitin Sulfate  Glycosaminoglycans  Oligosaccharides  
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
Authors:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
Favorite  |  View/Download：297/0  |  Submit date：2018/11/12
Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization  
Similar geometric rules govern the distribution of veins and stomata in petals, sepals and leaves 期刊论文
NEW PHYTOLOGIST, 2018, 卷号: 219, 期号: 4, 页码: 1224-1234
Authors:  Zhang, Feng-Ping;  Carins Murphy, Madeline R.;  Cardoso, Amanda A.;  Jordan, Gregory J.;  Brodribb, Timothy J.
View  |  Adobe PDF(1467Kb)  |  Favorite  |  View/Download：69/11  |  Submit date：2018/09/17
Epidermal Cell Size  Floral Evolution  Hydraulics  Stomatal Density  Vein Density  
Discovery of novel wee1 inhibitors via structure-based virtual screening and biological evaluation 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2018, 卷号: 32, 期号: 9, 页码: 901-915
Authors:  Li, Yaping;  Pu, Yinglan;  Liu, Hui;  Zhang, Li;  Liu, Xingyong;  Li, Yan;  Zuo, Zhili
Favorite  |  View/Download：327/0  |  Submit date：2018/11/06
Wee1 inhibitors  Pharmacophore model  Molecular docking  Virtual screening  Molecular dynamics simulation