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A new sesquiterpene synthase catalyzing the formation of (R)-fi-bisabolene from medicinal plant Colquhounia coccinea var. mollis and its anti-adipogenic and antibacterial activities 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 211, 页码: 113681
Authors:  Li,De-Sen;  Shi,Lin-Lin;  Guo,Kai;  Luo,Shi-Hong;  Liu,Yan-Chun;  Chen,Yue-Gui;  Liu,Yan;  Li,Sheng-Hong
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Sesquiterpenoids  Sesquiterpene synthases  (R)-fi-bisabolene  Colquhounia coccinea var  mollis  Anti-adipogenic activity  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  FUNCTIONAL EXPRESSION  BETA-BISABOLENE  ESSENTIAL OILS  BIOSYNTHESIS  IDENTIFICATION  CYTOTOXICITY  CLONING  
Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum 期刊论文
NEW PHYTOLOGIST, 2021, 卷号: 229, 期号: 3, 页码: 1740-1754
Authors:  Liu,Yan;  Luo,Shi-Hong;  Hua,Juan;  Li,De-Sen;  Ling,Yi;  Luo,Qian;  Li,Sheng-Hong
View  |  Adobe PDF(1889Kb)  |  Favorite  |  View/Download：405/90  |  Submit date：2022/04/02
cadinenes  defensive chemicals  Eupatorium adenophorum  sesquiterpenes  sesquiterpene synthase  NATURAL-PRODUCTS  FUNCTIONAL-CHARACTERIZATION  ABSOLUTE STEREOCHEMISTRY  TERPENE SYNTHASES  EXPRESSION  CLONING  EMISSION  LEAVES  GENES  9-OXO-10,11-DEHYDROAGERAPHORONE  
Immunosuppressive and Adipogenesis Inhibitory Sesterterpenoids with a Macrocyclic Ether System from Eurysolen gracilis 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 6, 页码: 2232-2237
Authors:  Teng,Lin-Lin;  Mu,Rong-Fang;  Liu,Yan-Chun;  Xiao,Chao-Jiang;  Li,De-Sen;  Gao,Jian-Xiong;  Guo,Kai;  Li,Xiao-Nian;  Liu,Yan;  Zeng,Fang;  Li,Sheng-Hong
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A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
Authors:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
View  |  Adobe PDF(2177Kb)  |  Favorite  |  View/Download：252/81  |  Submit date：2022/04/02
enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
Cloning and Functional Characterization of a Squalene Synthase from Paris polyphylla var. yunnanensis 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 卷号: 18, 期号: 7
Authors:  Gao,Jian-Xiong;  Chen,Yue-Gui;  Li,De-Sen;  Lin,Liang;  Liu,Yan;  Li,Sheng-Hong
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Paris polyphylla var  Yunnanensis  squalene synthase  steroidal saponins  squalene  in vitro enzymatic assay  MOLECULAR-CLONING  SAPONINS  EXPRESSION  GENE  GLYCOSIDES  PLANTS  SQS  
An extremely promiscuous terpenoid synthase from the Lamiaceae plant Colquhounia coccinea var. mollis catalyzes the formation of sester-/di-/sesqui-/mono-terpenoids 期刊论文
PLANT COMMUNICATIONS, 2021, 卷号: 2, 期号: 5, 页码: 100233
Authors:  Li,De-Sen;  Hua,Juan;  Luo,Shi-Hong;  Liu,Yan-Chun;  Chen,Yue-Gui;  Ling,Yi;  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
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terpenoid diversity  terpenoid synthase  promiscuous enzyme  sester-/di-/sesqui-/mono-terpenoids  Colquhounia coccinea var  mollis  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  DITERPENE SYNTHASE  LEUCOSCEPTRUM-CANUM  IDENTIFICATION  BRASSICACEAE  BIOLOGY  FAMILY  HARBOR  GENES  
Detoxification of Plant Aromatic Abietanoids via Cleavage of the Benzene Ring into 11,12-Seco-diterpene Polyenes by a Specialist Insect of Leucosceptrum canum 期刊论文
ORGANIC LETTERS, 2020, 卷号: 22, 期号: 1, 页码: 126-129
Authors:  Guo, Kai;  Liu, Yan;  Luo, Shi-Hong;  Liu, Yan-Chun;  Li, De-Sen;  Li, Wen-Yuan;  Li, Sheng-Hong
Favorite  |  View/Download：211/0  |  Submit date：2020/03/18
Unusual glycosidic labdane diterpenoids with cytotoxicity from the root of Phlomoides betonicoides 期刊论文
PHYTOCHEMISTRY, 2020
Authors:  Geng, Hao;  Liu, Yan-Chun;  Li, De-Sen;  Xiao, Chao-Jiang;  Liu, Yan;  Li, Xiao-Nian;  Li, Sheng-Hong
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Peltate glandular trichomes of Colquhounia vestita harbor diterpenoid acids that contribute to plant adaptation to UV radiation and cold stresses 期刊论文
PHYTOCHEMISTRY, 2020
Authors:  Tang, Ting;  Li, Chun-Huan;  Li, De-Sen;  Jing, Shu-Xi;  Hua, Juan;  Luo, Shi-Hong;  Liu, Yan;  Li, Sheng-Hong
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Production of the Inaccessible Sesquiterpene (-)-5-Epieremophilene by Metabolically EngineeredEscherichia coli 期刊论文
CHEMISTRY & BIODIVERSITY, 2020
Authors:  Luo, Liu-Qiong;  Chen, Yue-Gui;  Li, De-Sen;  Liu, Yan;  Li, Sheng-Hong
View  |  Adobe PDF(1985Kb)  |  Favorite  |  View/Download：467/99  |  Submit date：2021/01/05