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A chromosome-scale Gastrodia elata genome and large-scale comparative genomic analysis indicate convergent evolution by gene loss in mycoheterotrophic and parasitic plants 期刊论文
PLANT JOURNAL, 2021, 卷号: 108, 期号: 6, 页码: 1609-1623
Authors:  Xu,Yuxing;  Lei,Yunting;  Su,Zhongxiang;  Zhao,Man;  Zhang,Jingxiong;  Shen,Guojing;  Wang,Lei;  Li,Jing;  Qi,Jinfeng;  Wu,Jianqiang
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Gastrodia elata  mycoheterotrophic plant  parasitic plant  gene loss  convergent evolution  BIOSYNTHESIS  VITAMIN-K-1  TRANSPORT  SYMBIOSIS  ACID  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
Authors:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
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Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
Discovery of quality markers in Rubus Chingii Hu using UPLC-ESI-QTOF-MS 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 203, 页码: 114200
Authors:  Zhou,Zi-Meng;  Yan,Dong-Mei;  Wang,Yi-Kun;  Zhang,Ting;  Xiao,Xue-Rong;  Dai,Man-Yun;  Zhang,Shou-Wen;  Liu,Hong-Ning;  Li,Fei
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Raspberry  Q-markers  Quality evaluation  UPLC-ESI-QTOF-MS  COMPONENTS  ACTIVATION  PATHWAY  FRUITS  
Cordyceps polysaccharide marker CCP modulates immune responses via highly selective TLR4/MyD88/p38 axis 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 271, 页码: 118443
Authors:  Zhang,Quanwei;  Liu,Man;  Li,Lifeng;  Chen,Miaomiao;  Puno,Pema Tenzin;  Bao,Wanrong;  Zheng,Hongming;  Wen,Xin;  Cheng,Huiyuan;  Fung,Hauyee;  Wong,Tinlong;  Zhao,Zhongzhen;  Lyu,Aiping;  Han,Quanbin;  Sun,Handong
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Cordyceps  Polysaccharide  TLR4  MyD88  p38  Immune responses  Macrophage  NF-KAPPA-B  STRUCTURAL-CHARACTERIZATION  ANTIOXIDANT ACTIVITY  MYCELIAL FERMENTATION  SIGNALING PATHWAYS  FRUITING BODIES  SINENSIS FUNGUS  GENE-EXPRESSION  LIPOPOLYSACCHARIDE  RECOGNITION  
Synthesis of nigranoic acid and manwuweizic acid derivatives as HDAC inhibitors and anti-inflammatory agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 109, 页码: 104728
Authors:  Ni,Dong-Xuan;  Wang,Qi;  Li,Yi-Ming;  Cui,Yi-Man;  Shen,Tian-Ze;  Li,Xiao-Li;  Sun,Han-Dong;  Zhang,Xing-Jie;  Zhang,Ruihan;  Xiao,Wei-Lie
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Natural products modification  HDAC inhibition  Inflammasome  Triterpenoid  SCHISANDRA-PROPINQUA  TRITERPENOIDS  MECHANISM  INJURY  
A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
Authors:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
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enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
Leucoabietenes A and B, rearranged abietane and ent-abietane diterpene hydrocarbons against resistant infectious fungus and bacterium from the leaves of Leucosceptrum canum 期刊论文
TETRAHEDRON LETTERS, 2021, 卷号: 81, 页码: 153356
Authors:  Zhang,Man-Wen;  Guo,Kai;  Zhang,Yu;  Teng,Lin-Lin;  Huang,Qing-Pu;  Liu,Yan;  Li,Sheng-Hong
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Leucosceptrum canum  Ent-abietane diterpene  Abietane diterpene  Antimicrobial activity  TERPENOIDS  
Traditional Chinese medicine compound, Bu Sheng Hui Yang Fang, promotes the proliferation of lymphocytes in the immunosuppressed mice potentially by upregulating IL-4 signaling 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 134, 页码: 111107
Authors:  Wang,Yajie;  Tan,Jiabin;  Hu,Peng;  Pei,Qiang;  Wen,Yan;  Ma,Wenqing;  Shi,Keqian;  Li,Zengzheng;  Li,Huiyuan;  Cheng,Fengyu;  Gu,Xuezhong;  Yao,Xiangmei;  Man,Yan;  Zhao,Renbin;  Feng,Shuai;  Ding,Xiao;  Yang,Tonghua
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Bu Shen Hui Yang Fang (BSHY)  Immunoenhancement  Lymphocytes  Proliferation  Cytokine  IL-4  ACUTE MYELOID-LEUKEMIA  IMMUNE-SYSTEM  CANCER  CELLS  IMMUNOSURVEILLANCE  EXPRESSION  
A specific and bioactive polysaccharide marker for Cordyceps 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118343
Authors:  Li,Li-Feng;  But,Grace Wing-Chiu;  Zhang,Quan-Wei;  Liu,Man;  Chen,Miao-Miao;  Wen,Xin;  Wu,Hoi-Yan;  Cheng,Hui-Yuan;  Puno,Pema-Tenzin;  Zhang,Ji-Xia;  Fung,Hau-Yee;  Bai,Su-Ping;  Wong,Tin-Long;  Zhao,Zhong-Zhen;  Cao,Hui;  Tsim,Karl Wah-Keung;  Shaw,Pang-Chui;  Han,Quan-Bin;  Sun,Han-Dong
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Cordyceps  Polysaccharide  Marker  Authentication  Immune activity  STRUCTURAL-ANALYSIS  SINENSIS  AUTHENTICATION  MACROPHAGES  SEQUENCE  
Polyamine metabolism links gut microbiota and testicular dysfunction 期刊论文
MICROBIOME, 2021, 卷号: 9, 期号: 1, 页码: 224
Authors:  Zhao,Qi;  Huang,Jian-Feng;  Cheng,Yan;  Dai,Man-Yun;  Zhu,Wei-Feng;  Yang,Xiu-Wei;  Gonzalez,Frank J.;  Li,Fei
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Testicular dysfunction  Gut microbiota  Polyamine metabolism  Metabolomics  SMALL-MOLECULE INHIBITOR  ORNITHINE-DECARBOXYLASE  TRIPTOLIDE  SPERMINE  ACTIVATION  DISRUPTION  MECHANISMS  EXPRESSION  APOPTOSIS  TRANSPORT