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Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating [4+2] cycloaddition and target differentiation of enantiomers 期刊论文
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 4
Authors:  He, Tao-Bin;  Yan, Bing-Chao;  Zhou, Yuan-Fei;  Sang, Yue-Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Wang, Chu;  Xue, Xiao-Song;  Puno, Pema-Tenzin
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DIELS-ALDER REACTION  BIOMIMETIC SYNTHESES  EFFICIENT ACCESS  DEHYDROGENATION  CYCLOHEXANONES  BIOSYNTHESIS  CONVERSION  OXIDATION  DYNAMICS  PHENOLS  
Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 11, 期号: 1, 页码: 37-46
Authors:  Dai,Jia-Meng;  Yan,Bing-Chao;  Kong,Ling-Mei;  Hu,Kun;  Li,Xing-Ren;  Li,Xiao-Nian;  Sun,Han-Dong;  Li,Yan;  Puno,Pema-Tenzin
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ENT-KAURANE DITERPENOIDS  ABIETANE DITERPENOIDS  A-D  DIMERS  OXIDATION  CYCLOADDUCTS  ACTIVATION  LIGANDS  IBX  
Four new lanostane triterpenoids featuring extended pi-conjugated systems from the stems of Kadsura coccinea. 期刊论文
Natural products and bioprospecting, 2023, 卷号: 13, 期号: 1, 页码: 12-12
Authors:  Zhang, Qi-Qi;  Hu, Kun;  Sun, Han-Dong;  Puno, Pema-Tenzin
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A Modified 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedrae Herba Samples 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 14, 页码: 11272
Authors:  Li,Yue-Chiun;  Wu,Chia-Hung;  Le,Thi Ha;  Yuan,Qingjun;  Huang,Luqi;  Chen,Guo-Fen;  Yang,Mei-Lin;  Lam,Sio-Hong;  Hung,Hsin-Yi;  Sun,Handong;  Wu,Yi-Hung;  Kuo,Ping-Chung;  Wu,Tian-Shung
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ephedrine alkaloid  Ephedrae Herba  cyclized derivative  quantitative nuclear magnetic resonance spectroscopy (qNMR)  two-dimensional NMR (2D NMR)  QUANTITATIVE-ANALYSIS  PSEUDOEPHEDRINE  CHROMATOGRAPHY  URINE  SINICA  (-)-EPHEDRINE  SUPPLEMENTS  EXTRACTION  DRUGS  
Cordyceps polysaccharide marker CCP modulates immune responses via highly selective TLR4/MyD88/p38 axis 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 271, 页码: 118443
Authors:  Zhang,Quanwei;  Liu,Man;  Li,Lifeng;  Chen,Miaomiao;  Puno,Pema Tenzin;  Bao,Wanrong;  Zheng,Hongming;  Wen,Xin;  Cheng,Huiyuan;  Fung,Hauyee;  Wong,Tinlong;  Zhao,Zhongzhen;  Lyu,Aiping;  Han,Quanbin;  Sun,Handong
Favorite  |  View/Download:87/0  |  Submit date:2022/04/02
Cordyceps  Polysaccharide  TLR4  MyD88  p38  Immune responses  Macrophage  NF-KAPPA-B  STRUCTURAL-CHARACTERIZATION  ANTIOXIDANT ACTIVITY  MYCELIAL FERMENTATION  SIGNALING PATHWAYS  FRUITING BODIES  SINENSIS FUNGUS  GENE-EXPRESSION  LIPOPOLYSACCHARIDE  RECOGNITION  
Synthesis of nigranoic acid and manwuweizic acid derivatives as HDAC inhibitors and anti-inflammatory agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 109, 页码: 104728
Authors:  Ni,Dong-Xuan;  Wang,Qi;  Li,Yi-Ming;  Cui,Yi-Man;  Shen,Tian-Ze;  Li,Xiao-Li;  Sun,Han-Dong;  Zhang,Xing-Jie;  Zhang,Ruihan;  Xiao,Wei-Lie
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Natural products modification  HDAC inhibition  Inflammasome  Triterpenoid  SCHISANDRA-PROPINQUA  TRITERPENOIDS  MECHANISM  INJURY  
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 11, 页码: 7404-7421
Authors:  Zhou,Zongyuan;  Li,Yiming;  Ma,Xiaofang;  Cao,Biyun;  Peng,Ting;  Sheng,Yuwen;  Peng,Huipan;  Li,Runze;  Cao,Yu;  Xi,Ruiying;  Li,Fu;  Wang,Mengru;  Sun,Handong;  Zhang,Guolin;  Zhang,Hongbin;  Hu,Kaifeng;  Xiao,Weilie;  Wang,Fei
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GOMISIN-A  DIBENZOCYCLOOCTADIENE LIGNANS  SCHISANDRA-CHINENSIS  MASS-SPECTROMETRY  MIRNA EXPRESSION  DOWN-REGULATION  NONCODING RNA  MICRORNA  LIVER  DICER  
Tangutidines A-C, Three Amphoteric Diterpene Alkaloids from Aconitum tanguticum. 期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 4, 页码: 459-464
Authors:  Li,Hao-Yi;  Yan,Bing-Chao;  Wei,Li-Xin;  Sun,Han-Dong;  Puno,Pema-Tenzin
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A specific and bioactive polysaccharide marker for Cordyceps 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118343
Authors:  Li,Li-Feng;  But,Grace Wing-Chiu;  Zhang,Quan-Wei;  Liu,Man;  Chen,Miao-Miao;  Wen,Xin;  Wu,Hoi-Yan;  Cheng,Hui-Yuan;  Puno,Pema-Tenzin;  Zhang,Ji-Xia;  Fung,Hau-Yee;  Bai,Su-Ping;  Wong,Tin-Long;  Zhao,Zhong-Zhen;  Cao,Hui;  Tsim,Karl Wah-Keung;  Shaw,Pang-Chui;  Han,Quan-Bin;  Sun,Han-Dong
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Cordyceps  Polysaccharide  Marker  Authentication  Immune activity  STRUCTURAL-ANALYSIS  SINENSIS  AUTHENTICATION  MACROPHAGES  SEQUENCE  
Chaetolactam A, an Azaphilone Derivative from the Endophytic Fungus Chaetomium sp. g1 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 1, 页码: 475-483
Authors:  Zu,Wen-Yu;  Tang,Jian-Wei;  Hu,Kun;  Zhou,Yuan-Fei;  Gou,Lei-Lei;  Su,Xiao-Zheng;  Lei,Xinxiang;  Sun,Han-Dong;  Puno,Pema-Tenzin
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MASS-SPECTROMETRY  A-D  CASPASE-3  H-1