Labdane diterpenoids from the heartwood of Leucosceptrum canum that impact on root growth and seed germination of Arabidopsis thaliana

doi:10.1016/j.phytochem.2022.113531

KIB OpenIR

	Labdane diterpenoids from the heartwood of Leucosceptrum canum that impact on root growth and seed germination of Arabidopsis thaliana
	Liu,Yan; Zhou,Yan-Ying; Luo,Shi-Hong; Guo,Kai; Zhang,Man-Wen; Jing,Shu-Xi; Li,Chun-Huan; Hua,Juan; Li,Sheng-Hong
	2023
Source Publication	PHYTOCHEMISTRY
ISSN	1873-3700
Volume	206 Pages:113531
Abstract	Eleven undescribed diterpenoids possessing labdane, 3,18-cyclo-labdane, 19 (4 -> 3)-labdane and 12-nor-labdane skeletons, named leucolactones A-K, were isolated from the heartwood of a large woody Lamiaceae plant, Leucosceptrum canum. Their structures were determined by NMR, MS, and in the case of leucolactones A by single crystal X-ray diffraction analysis. Plausible biosynthetic pathway of leucolactones were proposed. Leucolactones showed significant inhibitory effects against seed germination and root elongation of Arabidopsis thaliana in the Petri dish bioassay. Among them, the diastereomeric leucolactones G and H were the most potent, with EC50 values for root elongation of 6.53 +/- 1.35 and 9.75 +/- 1.25 mu M, respectively. The preliminary structure-activity relationship of leucolactones was discussed. The increase of auxin reporter activity in A. thaliana DR5::GUS roots by leucolactone H was observed, indicating that leucolactones altered auxin accumulation and distribution. These findings suggested that leucolactones might be involved in regulation of plant growth and development through altering auxin accumulation and distribution, presumably contributing to the heartwood formation in L. canum.
Keyword	Leucosceptrum canum Lamiaceae Labdane diterpenoids Leucolactones A-K Phytotoxic activity Auxin accumulation GLANDULAR TRICHOMES COLORED NECTAR AUXIN TRANSPORT GRADIENT WOOD
Subject Area	Biochemistry & Molecular Biology ; Plant Sciences
DOI	10.1016/j.phytochem.2022.113531
Indexed By	SCI
WOS ID	WOS:000903504400013
Citation statistics
Document Type	期刊论文
Identifier	http://ir.kib.ac.cn/handle/151853/75431
Collection	中国科学院昆明植物研究所
Recommended Citation GB/T 7714	Liu,Yan,Zhou,Yan-Ying,Luo,Shi-Hong,et al. Labdane diterpenoids from the heartwood of Leucosceptrum canum that impact on root growth and seed germination of Arabidopsis thaliana[J]. PHYTOCHEMISTRY,2023,206:113531.
APA	Liu,Yan.,Zhou,Yan-Ying.,Luo,Shi-Hong.,Guo,Kai.,Zhang,Man-Wen.,...&Li,Sheng-Hong.(2023).Labdane diterpenoids from the heartwood of Leucosceptrum canum that impact on root growth and seed germination of Arabidopsis thaliana.PHYTOCHEMISTRY,206,113531.
MLA	Liu,Yan,et al."Labdane diterpenoids from the heartwood of Leucosceptrum canum that impact on root growth and seed germination of Arabidopsis thaliana".PHYTOCHEMISTRY 206(2023):113531.

Files in This Item:		Download All
File Name/Size	DocType	Version	Access	License
1-s2.0-S003194222200（5161KB）	期刊论文	出版稿	开放获取	CC BY-NC-SA	View Download

File name:	1-s2.0-S0031942222004472-main.pdf
Format:	Adobe PDF

If you have any objections to this item, please fill out the form below and the administrator will contact you as soon as possible.
Content:
Email：	*
Institution:
Verification Code:	Refresh

Any comments and suggestions are welcomed.
Title:	*
Content:
Email：	*
Verification Code:	Refresh

中国科学院昆明植物研究所知识管理系统