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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
Authors:
Wang,Yi-Ting
;
Long,Xin-Yan
;
Ding,Xiao
;
Fan,Shi-Rui
;
Cai,Jie-Yun
;
Yang,Bi-Juan
;
Zhang,Xin-Fang
;
Luo,Rong-hua
;
Yang,Lian
;
Ruan,Ting
;
Ren,Juan
;
Jing,Chen-Xu
;
Zheng,Yong-Tang
;
Hao,Xiao-Jiang
;
Chen,Duo-Zhi
Favorite
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View/Download:47/0
  |  
Submit date:2022/04/02
Phenanthridine
Nucleocapsid protein
SARS-CoV-2
N-terminal domain
N-TERMINAL DOMAIN
CORONAVIRUS
Immunostimulatory 6/6/6/6 Tetracyclic Triterpenoid Saponins with the Methyl-30 Incorporated Cyclization from the Root of Colquhounia elegans
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 19, 页码: 7462-7466
Authors:
Hua,Juan
;
Liu,Yan-Chun
;
Luo,Shi-Hong
;
Liu,Yan
;
Xiao,Chao-Jiang
;
Li,Xiao-Nian
;
Li,Sheng-Hong
Favorite
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View/Download:15/0
  |  
Submit date:2022/04/02
QUILLAJA-SAPONARIA
BIOSYNTHESIS
MECHANISMS
ADJUVANTS
VARIANTS
PRODUCTS
CYCLASE
An extremely promiscuous terpenoid synthase from the Lamiaceae plant Colquhounia coccinea var. mollis catalyzes the formation of sester-/di-/sesqui-/mono-terpenoids
期刊论文
PLANT COMMUNICATIONS, 2021, 卷号: 2, 期号: 5, 页码: 100233
Authors:
Li,De-Sen
;
Hua,Juan
;
Luo,Shi-Hong
;
Liu,Yan-Chun
;
Chen,Yue-Gui
;
Ling,Yi
;
Guo,Kai
;
Liu,Yan
;
Li,Sheng-Hong
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View/Download:17/0
  |  
Submit date:2022/04/02
terpenoid diversity
terpenoid synthase
promiscuous enzyme
sester-/di-/sesqui-/mono-terpenoids
Colquhounia coccinea var
mollis
GERANYLFARNESYL DIPHOSPHATE SYNTHASE
GLANDULAR TRICHOMES
DITERPENE SYNTHASE
LEUCOSCEPTRUM-CANUM
IDENTIFICATION
BRASSICACEAE
BIOLOGY
FAMILY
HARBOR
GENES
A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
Authors:
Chen,Yue-Gui
;
Li,De-Sen
;
Ling,Yi
;
Liu,Yan-Chun
;
Zuo,Zhi-Li
;
Gan,Li-She
;
Luo,Shi-Hong
;
Hua,Juan
;
Chen,Ding-Yuan
;
Xu,Fan
;
Li,Man
;
Guo,Kai
;
Liu,Yan
;
Gershenzon,Jonathan
;
Li,Sheng-Hong
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Submit date:2022/04/02
enzyme engineering
immunosuppressive activity
Leucosceptrum canum
macrocyclic terpenoids
sesterterpene synthase
GERANYLFARNESYL DIPHOSPHATE SYNTHASE
GLANDULAR TRICHOMES
LEUCOSCEPTRUM-CANUM
SCALE INSECT
SESTERTERPENOIDS
CONVERSION
EVOLUTION
PRECURSOR
HARBOR
Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum
期刊论文
NEW PHYTOLOGIST, 2021, 卷号: 229, 期号: 3, 页码: 1740-1754
Authors:
Liu,Yan
;
Luo,Shi-Hong
;
Hua,Juan
;
Li,De-Sen
;
Ling,Yi
;
Luo,Qian
;
Li,Sheng-Hong
Favorite
  |  
View/Download:13/0
  |  
Submit date:2022/04/02
cadinenes
defensive chemicals
Eupatorium adenophorum
sesquiterpenes
sesquiterpene synthase
NATURAL-PRODUCTS
FUNCTIONAL-CHARACTERIZATION
ABSOLUTE STEREOCHEMISTRY
TERPENE SYNTHASES
EXPRESSION
CLONING
EMISSION
LEAVES
GENES
9-OXO-10,11-DEHYDROAGERAPHORONE
Effects of 23-epi-26-deoxyactein on adipogenesis in 3T3-L1 preadipocytes and diet-induced obesity in C57BL/6 mice
期刊论文
PHYTOMEDICINE, 2020
Authors:
Yuan, Jingjing
;
Shi, Qiangqiang
;
Chen, Juan
;
Lu, Jing
;
Wang, Lu
;
Qiu, Minghua
;
Liu, Jian
Adobe PDF(1807Kb)
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View/Download:25/10
  |  
Submit date:2021/01/05
Peltate glandular trichomes of Colquhounia vestita harbor diterpenoid acids that contribute to plant adaptation to UV radiation and cold stresses
期刊论文
PHYTOCHEMISTRY, 2020
Authors:
Tang, Ting
;
Li, Chun-Huan
;
Li, De-Sen
;
Jing, Shu-Xi
;
Hua, Juan
;
Luo, Shi-Hong
;
Liu, Yan
;
Li, Sheng-Hong
Adobe PDF(2106Kb)
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View/Download:32/11
  |  
Submit date:2021/01/05
Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum
期刊论文
NEW PHYTOLOGIST, 2020
Authors:
Liu, Yan
;
Luo, Shi-Hong
;
Hua, Juan
;
Li, De-Sen
;
Ling, Yi
;
Luo, Qian
;
Li, Sheng-Hong
Adobe PDF(30959Kb)
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  |  
Submit date:2021/01/05
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts
期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
Authors:
Yang, Jun-Li
;
Ma, Yong-Hui
;
Li, Yan-Hua
;
Zhang, Yi-Peng
;
Tian, Hong-Chang
;
Huang, Yuan-Cheng
;
Li, Yan
;
Chen, Wen
;
Yang, Li-Juan
Adobe PDF(2215Kb)
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View/Download:102/25
  |  
Submit date:2020/03/18
Leucosceptroid B from glandular trichomes of Leucosceptrum canum reduces fat accumulation in Caenorhabditis elegans through suppressing unsaturated fatty acid biosynthesis
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 892-899
Authors:
Ling Yi
;
Teng Lin-Lin
;
Hua Juan
;
Li De-Sen
;
Luo Shi-Hong
;
Liu Yan-Chun
;
Liu Yan
;
Li Sheng-Hong
Adobe PDF(1517Kb)
  |  
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View/Download:138/13
  |  
Submit date:2020/03/18
Sesterterpenoid
Leucosceptroid B
Leucosceptrum canum
Caenorhabditis elegans
Fat accumulation
Fatty acid biosynthesis
Antilipemic agent