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A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
Authors:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
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enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
Immunosuppresive Sesterterpenoids and Norsesterterpenoids from Colquhounia coccinea var. mollis 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 16, 页码: 11169-11176
Authors:  Jing,Shu-Xi;  Fu,Ran;  Li,Chun-Huan;  Zhou,Ting-Ting;  Liu,Yan-Chun;  Liu,Yan;  Luo,Shi-Hong;  Li,Xiao-Nian;  Zeng,Fang;  Li,Sheng-Hong
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LEUCOSCEPTRUM-CANUM  GLANDULAR TRICHOMES  PRODUCTS  FAMILY  HARBOR  
Immunosuppressive and Adipogenesis Inhibitory Sesterterpenoids with a Macrocyclic Ether System from Eurysolen gracilis 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 6, 页码: 2232-2237
Authors:  Teng,Lin-Lin;  Mu,Rong-Fang;  Liu,Yan-Chun;  Xiao,Chao-Jiang;  Li,De-Sen;  Gao,Jian-Xiong;  Guo,Kai;  Li,Xiao-Nian;  Liu,Yan;  Zeng,Fang;  Li,Sheng-Hong
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An extremely promiscuous terpenoid synthase from the Lamiaceae plant Colquhounia coccinea var. mollis catalyzes the formation of sester-/di-/sesqui-/mono-terpenoids 期刊论文
PLANT COMMUNICATIONS, 2021, 卷号: 2, 期号: 5, 页码: 100233
Authors:  Li,De-Sen;  Hua,Juan;  Luo,Shi-Hong;  Liu,Yan-Chun;  Chen,Yue-Gui;  Ling,Yi;  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
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terpenoid diversity  terpenoid synthase  promiscuous enzyme  sester-/di-/sesqui-/mono-terpenoids  Colquhounia coccinea var  mollis  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  DITERPENE SYNTHASE  LEUCOSCEPTRUM-CANUM  IDENTIFICATION  BRASSICACEAE  BIOLOGY  FAMILY  HARBOR  GENES  
Immunosuppressive gentianellane-type sesterterpenoids from the traditional Uighur medicine Gentianella turkestanorum 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 187, 页码: 112780
Authors:  Guo,Kai;  Liu,Yan-Chun;  Liu,Yan;  Zhang,Han;  Li,Wen-Yuan;  Shi,Qiu-Mei;  Li,Xiao-Nian;  Zeng,Fang;  Li,Sheng-Hong
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Gentianella turkestanorum  Gentianaceae  Plant sesterterpenoids  Gentianellane-type  Immunosuppressive activity  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  CONSTITUENTS  PRODUCTS  HARBOR  
The untapped potential of plant sesterterpenoids: chemistry, biological activities and biosynthesis 期刊论文
NATURAL PRODUCT REPORTS, 2021, 卷号: 38, 期号: 12, 页码: 2293-2314
Authors:  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
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LEUCOSCEPTRUM-CANUM  GLANDULAR TRICHOMES  FERN CONSTITUENTS  AERIAL PARTS  ABSOLUTE STEREOCHEMISTRY  SALVIA  CYCLIZATION  SYNTHASES  NORSESTERTERPENES  CONFIGURATION  
Unusual glycosidic labdane diterpenoids with cytotoxicity from the root of Phlomoides betonicoides 期刊论文
PHYTOCHEMISTRY, 2020
Authors:  Geng, Hao;  Liu, Yan-Chun;  Li, De-Sen;  Xiao, Chao-Jiang;  Liu, Yan;  Li, Xiao-Nian;  Li, Sheng-Hong
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Peltate glandular trichomes of Colquhounia vestita harbor diterpenoid acids that contribute to plant adaptation to UV radiation and cold stresses 期刊论文
PHYTOCHEMISTRY, 2020
Authors:  Tang, Ting;  Li, Chun-Huan;  Li, De-Sen;  Jing, Shu-Xi;  Hua, Juan;  Luo, Shi-Hong;  Liu, Yan;  Li, Sheng-Hong
View  |  Adobe PDF(2106Kb)  |  Favorite  |  View/Download：23/7  |  Submit date：2021/01/05
Leucosceptroid B from glandular trichomes of Leucosceptrum canum reduces fat accumulation in Caenorhabditis elegans through suppressing unsaturated fatty acid biosynthesis 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 892-899
Authors:  Ling Yi;  Teng Lin-Lin;  Hua Juan;  Li De-Sen;  Luo Shi-Hong;  Liu Yan-Chun;  Liu Yan;  Li Sheng-Hong
View  |  Adobe PDF(1517Kb)  |  Favorite  |  View/Download：127/11  |  Submit date：2020/03/18
Sesterterpenoid  Leucosceptroid B  Leucosceptrum canum  Caenorhabditis elegans  Fat accumulation  Fatty acid biosynthesis  Antilipemic agent  
Anti-BACE1 and anti-AchE activities of undescribed spiro-dioxolane-containing meroterpenoids from the endophytic fungus Aspergillus terreus Thom 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 165, 页码: 8
Authors:  Qi, Changxing;  Zhou, Qun;  Gao, Weixi;  Liu, Mengting;  Chen, Chunmei;  Li, Xiao-Nian;  Lai, Yongji;  Zhou, Yuan;  Li, Dongyan;  Hu, Zhengxi;  Zhu, Hucheng;  Zhang, Yonghui
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Aspergillus terreus Thom  endophytic fungus  3,5-Dimethylorsellinic acid-based meroterpenoid  Adducts  Alzheimer's disease