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Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 11, 页码: UNSP 1934
作者:  Song, Lihua;  Wang, Zhe;  Wang, Yurong;  Guo, Di;  Yang, Jianhong;  Chen, Lijuan;  Tan, Ninghua
浏览  |  Adobe PDF(4110Kb)  |  收藏  |  浏览/下载：158/37  |  提交时间：2018/05/08
Ra-xii  Cyclopeptide  Autophagy  Apoptosis  Mtor  Hepg2 Liver Cancer Cells  
Potential role of CYP1B1 in the development and treatment of metabolic diseases 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2017, 卷号: 178, 页码: 18-30
作者:  Li, Fei;  Zhu, Weifeng;  Gonzalez, Frank J.
浏览  |  Adobe PDF(2083Kb)  |  收藏  |  浏览/下载：187/61  |  提交时间：2017/11/20
Cyp1b1  Metabolic Diseases  Metabolic Pathways  Metabolomics  
Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 8, 页码: 2319-2327
作者:  Xu, Yuhui;  Niu, Yanfen;  Gao, Yuan;  Wang, Fang;  Qin, Wanying;  Lu, Yanting;  Hu, Jing;  Peng, Li;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4940Kb)  |  收藏  |  浏览/下载：372/59  |  提交时间：2017/10/23
Insulin-resistance  Tuberculata Beumee  Metabolic Syndrome  Srebp  Liver  Cholesterol  Constituents  Homeostasis  Inhibition  Receptors  
Synthesis of selective 11 beta-HSD1 inhibitors based on dammarane scaffold 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 135, 页码: 324-338
作者:  Shao, Li-Dong;  Bao, Ying;  Shen, Yu;  Su, Jia;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1336Kb)  |  收藏  |  浏览/下载：317/73  |  提交时间：2017/07/31
11 Beta-hsd1 Inhibitor  Hupehenols  Dammarane  Sar  
1,4-Naphthoquinone Triggers Nematode Lethality by Inducing Oxidative Stress and Activating Insulin/IGF Signaling Pathway in Caenorhabditis elegans10.3390/molecules22050798 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 5, 页码: 798
作者:  Wang, Jia;  Zeng, Guangzhi;  Huang, Xiaobing;  Wang, Zhe;  Tan, Ninghua
浏览  |  Adobe PDF(3070Kb)  |  收藏  |  浏览/下载：209/30  |  提交时间：2017/07/31
Plant-parasitic Nematode  Phytochemical  Nematocidal  Oxidative Stress  1  Insulin/igf Signaling Pathway  4-naphthoquinone  Caenorhabditis Elegans  
Quantitative proteomics analysis of Caenorhabditis elegans upon germ cell loss 期刊论文
JOURNAL OF PROTEOMICS, 2017, 卷号: 156, 期号: 1, 页码: 85-93
作者:  Pu, Yuan-Zhu;  Wan, Qin-Li;  Ding, Ai-Jun;  Luo, Huai-Rong;  Wu, Gui-Sheng
浏览  |  Adobe PDF(1197Kb)  |  收藏  |  浏览/下载：319/105  |  提交时间：2017/05/19
Caenorhabditis Elegans  Proteomics  Aging  Notch Receptor Glp-1  Reproduction  
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:  Yang, Na;  Sun, Run-Bin;  Chen, Xing-Long;  Zhen, Le;  Ge, Chun;  Zhao, Yu-Qing;  He, Jun;  Geng, Jian-Liang;  Guo, Jia-Hua;  Yu, Xiao-Yi;  Fei, Fei;  Feng, Si-Qi;  Zhu, Xuan-Xuan;  Wang, Hong-Bo;  Fu, Feng-Hua;  Aa, Ji-Ye;  Wang, Guang-Ji
浏览  |  Adobe PDF(4661Kb)  |  收藏  |  浏览/下载：268/89  |  提交时间：2017/05/19
Hyperglycemia  Glucose-lowering Effect  Berberine  Berberrubine  Glucuronide  Alpha-glycosidase  Hfd-induced Hyperglycemia Model Of C57bl/6 Mice  Human Normal Liver Cell Line L-o2  Pharmacokinetics  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
浏览  |  Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：456/207  |  提交时间：2017/02/28
Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 期号: 0, 页码: 42176
作者:  Li, Mingyue;  Song, Li-Hua;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Zhao, Li-Mei;  Li, Lin;  Zhou, Xunian;  Tsui, Stephen Kwok-Wing;  Ng, Simon Siu-Man;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
浏览  |  Adobe PDF(3294Kb)  |  收藏  |  浏览/下载：237/46  |  提交时间：2017/04/17
Star-PAP, a poly(A) polymerase, functions as a tumor suppressor in an orthotopic human breast cancer model 期刊论文
CELL DEATH & DISEASE, 2017, 卷号: 8, 期号: 1, 页码: e2582
作者:  Yu, C.;  Gong, Y.;  Zhou, H.;  Wang, M.;  Kong, L.;  Liu, J.;  An, T.;  Zhu, H.;  Li, Y.
浏览  |  Adobe PDF(3022Kb)  |  收藏  |  浏览/下载：202/46  |  提交时间：2017/04/19