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A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
Authors:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
Favorite  |  View/Download：18/0  |  Submit date：2022/04/02
enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
An extremely promiscuous terpenoid synthase from the Lamiaceae plant Colquhounia coccinea var. mollis catalyzes the formation of sester-/di-/sesqui-/mono-terpenoids 期刊论文
PLANT COMMUNICATIONS, 2021, 卷号: 2, 期号: 5, 页码: 100233
Authors:  Li,De-Sen;  Hua,Juan;  Luo,Shi-Hong;  Liu,Yan-Chun;  Chen,Yue-Gui;  Ling,Yi;  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
Favorite  |  View/Download：16/0  |  Submit date：2022/04/02
terpenoid diversity  terpenoid synthase  promiscuous enzyme  sester-/di-/sesqui-/mono-terpenoids  Colquhounia coccinea var  mollis  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  DITERPENE SYNTHASE  LEUCOSCEPTRUM-CANUM  IDENTIFICATION  BRASSICACEAE  BIOLOGY  FAMILY  HARBOR  GENES  
Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum 期刊论文
NEW PHYTOLOGIST, 2021, 卷号: 229, 期号: 3, 页码: 1740-1754
Authors:  Liu,Yan;  Luo,Shi-Hong;  Hua,Juan;  Li,De-Sen;  Ling,Yi;  Luo,Qian;  Li,Sheng-Hong
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cadinenes  defensive chemicals  Eupatorium adenophorum  sesquiterpenes  sesquiterpene synthase  NATURAL-PRODUCTS  FUNCTIONAL-CHARACTERIZATION  ABSOLUTE STEREOCHEMISTRY  TERPENE SYNTHASES  EXPRESSION  CLONING  EMISSION  LEAVES  GENES  9-OXO-10,11-DEHYDROAGERAPHORONE  
Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum 期刊论文
NEW PHYTOLOGIST, 2020
Authors:  Liu, Yan;  Luo, Shi-Hong;  Hua, Juan;  Li, De-Sen;  Ling, Yi;  Luo, Qian;  Li, Sheng-Hong
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Leucosceptroid B from glandular trichomes of Leucosceptrum canum reduces fat accumulation in Caenorhabditis elegans through suppressing unsaturated fatty acid biosynthesis 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 892-899
Authors:  Ling Yi;  Teng Lin-Lin;  Hua Juan;  Li De-Sen;  Luo Shi-Hong;  Liu Yan-Chun;  Liu Yan;  Li Sheng-Hong
Adobe PDF(1517Kb)  |  Favorite  |  View/Download：138/13  |  Submit date：2020/03/18
Sesterterpenoid  Leucosceptroid B  Leucosceptrum canum  Caenorhabditis elegans  Fat accumulation  Fatty acid biosynthesis  Antilipemic agent  
Characterization of a sesquiterpene cyclase from the glandular trichomes of Leucosceptrum canum for sole production of cedrol in Escherichia coli and Nicotiana benthamiana 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 162, 页码: 121-128
Authors:  Luo, Fei;  Ling, Yi;  Li, De-Sen;  Tang, Ting;  Liu, Yan-Chun;  Liu, Yan;  Li, Sheng-Hong
View  |  Adobe PDF(2851Kb)  |  Favorite  |  View/Download：124/15  |  Submit date：2019/07/29
Leucosceptrum canum  Lamiaceae  Cedrol  Sesquiterpene cylase  Cedrol synthase  Heterologous production  Synthetic biology  
米团花萜类合酶功能鉴定和二倍半萜生物活性探索 学位论文
硕士, 2018
Authors:  凌伊
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Chemical constituents from Piper hainanense and their cytotoxicities 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2016, 卷号: 18, 期号: 8, 页码: 730-736
Authors:  Shi, Yan-Ni;  Xin, Ying;  Ling, Yi;  Li, Xing-Cong;  Hao, Chao-Yun;  Zhu, Hong-Tao;  Wang, Dong;  Yang, Chong-Ren;  Xu, Min;  Zhang, Ying-Jun
Adobe PDF(893Kb)  |  Favorite  |  View/Download：171/42  |  Submit date：2016/09/28
Piperaceae  Piper Hainanense  Cytotoxicity  Polyoxygenated Cyclohexene Derivatives  Benzene Derivatives  Pipoxide  
Carboline Alkaloids from Trigonostemon lii 期刊论文
PLANTA MEDICA, 2009, 卷号: 75, 期号: 10, 页码: 1157-1161
Authors:  Hu, Xu-Jia;  Di, Ying-Tong;  Wang, Yue-Hu;  Kong, Ling-Yi;  Gao, Suo;  Li, Chun-Shun;  Liu, Hai-Yang;  He, Hong-Ping;  Ding, Jian;  Xie, Hua;  Hao, Xiao-Jiang
Adobe PDF(11718Kb)  |  Favorite  |  View/Download：186/30  |  Submit date：2012/07/18
Trigonostemon Lii  Euphorbiaceae  Carboline Alkaloids  Cytotoxic Activity  
New phenanthrenes from Trigonostemon lii YT Chang 期刊论文
TETRAHEDRON LETTERS, 2009, 卷号: 50, 期号: 24, 页码: 2917-2919
Authors:  Hu, Xu-Jia;  Wang, Yue-Hu;  Kong, Ling-Yi;  He, Hong-Ping;  Gao, Suo;  Liu, Hai-Yang;  Ding, Jian;  Xie, Hua;  Di, Ying-Tong;  Hao, Xiao-Jiang
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Glochidion-coccineum  Reidioides  Daphnane  Rediocide  Roots  Plant  Assay