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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial
期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
Authors:
Gou,Zhong-Ping
;
Zhao,Yun-Li
;
Zou,Lin-Ling
;
Wang,Ying
;
Shu,Shi-Qing
;
Zhu,Xiao-Hong
;
Zheng,Li
;
Shen,Qi
;
Luo,Zhu
;
Miao,Jia
;
Wang,Yong-Sheng
;
Luo,Xiao-Dong
;
Feng,Ping
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Submit date:2022/04/02
Clinical safety
healthy subject
dose-escalation study
MONOTERPENOID INDOLE ALKALOIDS
FLIGHT MASS-SPECTROMETRY
EXTRACT
IDENTIFICATION
CONSTITUENTS
Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum
期刊论文
NEW PHYTOLOGIST, 2021, 卷号: 229, 期号: 3, 页码: 1740-1754
Authors:
Liu,Yan
;
Luo,Shi-Hong
;
Hua,Juan
;
Li,De-Sen
;
Ling,Yi
;
Luo,Qian
;
Li,Sheng-Hong
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Submit date:2022/04/02
cadinenes
defensive chemicals
Eupatorium adenophorum
sesquiterpenes
sesquiterpene synthase
NATURAL-PRODUCTS
FUNCTIONAL-CHARACTERIZATION
ABSOLUTE STEREOCHEMISTRY
TERPENE SYNTHASES
EXPRESSION
CLONING
EMISSION
LEAVES
GENES
9-OXO-10,11-DEHYDROAGERAPHORONE
Immunosuppresive Sesterterpenoids and Norsesterterpenoids from Colquhounia coccinea var. mollis
期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 16, 页码: 11169-11176
Authors:
Jing,Shu-Xi
;
Fu,Ran
;
Li,Chun-Huan
;
Zhou,Ting-Ting
;
Liu,Yan-Chun
;
Liu,Yan
;
Luo,Shi-Hong
;
Li,Xiao-Nian
;
Zeng,Fang
;
Li,Sheng-Hong
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Submit date:2022/04/02
LEUCOSCEPTRUM-CANUM
GLANDULAR TRICHOMES
PRODUCTS
FAMILY
HARBOR
Immunostimulatory 6/6/6/6 Tetracyclic Triterpenoid Saponins with the Methyl-30 Incorporated Cyclization from the Root of Colquhounia elegans
期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 19, 页码: 7462-7466
Authors:
Hua,Juan
;
Liu,Yan-Chun
;
Luo,Shi-Hong
;
Liu,Yan
;
Xiao,Chao-Jiang
;
Li,Xiao-Nian
;
Li,Sheng-Hong
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Submit date:2022/04/02
QUILLAJA-SAPONARIA
BIOSYNTHESIS
MECHANISMS
ADJUVANTS
VARIANTS
PRODUCTS
CYCLASE
A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
Authors:
Chen,Yue-Gui
;
Li,De-Sen
;
Ling,Yi
;
Liu,Yan-Chun
;
Zuo,Zhi-Li
;
Gan,Li-She
;
Luo,Shi-Hong
;
Hua,Juan
;
Chen,Ding-Yuan
;
Xu,Fan
;
Li,Man
;
Guo,Kai
;
Liu,Yan
;
Gershenzon,Jonathan
;
Li,Sheng-Hong
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Submit date:2022/04/02
enzyme engineering
immunosuppressive activity
Leucosceptrum canum
macrocyclic terpenoids
sesterterpene synthase
GERANYLFARNESYL DIPHOSPHATE SYNTHASE
GLANDULAR TRICHOMES
LEUCOSCEPTRUM-CANUM
SCALE INSECT
SESTERTERPENOIDS
CONVERSION
EVOLUTION
PRECURSOR
HARBOR
An extremely promiscuous terpenoid synthase from the Lamiaceae plant Colquhounia coccinea var. mollis catalyzes the formation of sester-/di-/sesqui-/mono-terpenoids
期刊论文
PLANT COMMUNICATIONS, 2021, 卷号: 2, 期号: 5, 页码: 100233
Authors:
Li,De-Sen
;
Hua,Juan
;
Luo,Shi-Hong
;
Liu,Yan-Chun
;
Chen,Yue-Gui
;
Ling,Yi
;
Guo,Kai
;
Liu,Yan
;
Li,Sheng-Hong
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Submit date:2022/04/02
terpenoid diversity
terpenoid synthase
promiscuous enzyme
sester-/di-/sesqui-/mono-terpenoids
Colquhounia coccinea var
mollis
GERANYLFARNESYL DIPHOSPHATE SYNTHASE
GLANDULAR TRICHOMES
DITERPENE SYNTHASE
LEUCOSCEPTRUM-CANUM
IDENTIFICATION
BRASSICACEAE
BIOLOGY
FAMILY
HARBOR
GENES
Rapid and unambiguous assignment of proton-deficient N-acyl amidine indole alkaloid by a combination of calculation methods
期刊论文
TETRAHEDRON LETTERS, 2021, 卷号: 68, 页码: 152949
Authors:
Ding,Cai-Feng
;
Yu,Hao-Fei
;
Shi,Xiao-Long
;
Ge,Shi-Cheng
;
Njateng,Guy S. S.
;
Qin,Xu-Jie
;
Dai,Zhi
;
Zhang,Rong-Ping
;
Zhang,Hong-Bin
;
Luo,Xiao-Dong
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Submit date:2022/04/02
N-acyl amidine
Voafriamidine
Calculation methods
Antimicrobial activity
ASSISTED STRUCTURE ELUCIDATION
APORPHINE
DERIVATIVES
C-13
TOOL
Antibacterial harziane diterpenoids from a fungal symbiont Trichoderma atroviride isolated from Colquhounia coccinea var. mollis
期刊论文
PHYTOCHEMISTRY, 2020, 卷号: 170, 页码: 7
Authors:
Li, Wen-Yuan
;
Liu, Yan
;
Lin, Yu-Tian
;
Liu, Yan-Chun
;
Guo, Kai
;
Li, Xiao-Nian
;
Luo, Shi-Hong
;
Li, Sheng-Hong
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Submit date:2020/03/18
Trichoderma atroviride
Hypocreaceae
Colquhounia coccinea var. mollis
Lamiaceae
Fungal endophyte
Harziane diterpenoids
Harzianols F-J
Antibacterial activity
Detoxification of Plant Aromatic Abietanoids via Cleavage of the Benzene Ring into 11,12-Seco-diterpene Polyenes by a Specialist Insect of Leucosceptrum canum
期刊论文
ORGANIC LETTERS, 2020, 卷号: 22, 期号: 1, 页码: 126-129
Authors:
Guo, Kai
;
Liu, Yan
;
Luo, Shi-Hong
;
Liu, Yan-Chun
;
Li, De-Sen
;
Li, Wen-Yuan
;
Li, Sheng-Hong
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Submit date:2020/03/18
Peltate glandular trichomes of Colquhounia vestita harbor diterpenoid acids that contribute to plant adaptation to UV radiation and cold stresses
期刊论文
PHYTOCHEMISTRY, 2020
Authors:
Tang, Ting
;
Li, Chun-Huan
;
Li, De-Sen
;
Jing, Shu-Xi
;
Hua, Juan
;
Luo, Shi-Hong
;
Liu, Yan
;
Li, Sheng-Hong
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View/Download:40/14
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Submit date:2021/01/05