Knowledge Management System of Kunming Institute of Botany,CAS
| New triterpenoids from the aerial parts of the Uygur medicine Salvia deserta | |
Ren,Xue; Yuan,Xin; Chen,Yu-Ying; Zhang,Qiao-Zhuo; Tan,Chun-Lin; Kang,Juan-Juan; Luo,Shi-Hong; Liu,Yan; Guo,Kai; Li,Sheng-Hong
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| 2023 | |
| Source Publication | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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| ISSN | 1477-2213 |
| Abstract | Phytochemical investigation on the aerial parts of Salvia deserta led to the isolation of eight new pentacyclic triterpenoids including three oleanane- (1 - 3) and five ursane-type (4 - 8) triterpenoids, whose structures were elucidated based on extensive spectroscopic analysis and quantum chemical calculation. Weak immunosuppressive potency was observed for compounds 1, 2, and 4 - 8 via inhibiting the secretion of cytokines TNF-alpha and IL-6 in LPS-induced macrophages RAW264.7 at 20 mu M. In addition, compounds 1, 2, and 4 - 6 exhibited moderate protective activity on t-BHP-induced oxidative injury in HepG2 cells. |
| Keyword | Lamiaceae Salvia deserta triterpenoids immunosuppressive activity hepatoprotective activity URSANE-TYPE TRITERPENES DITERPENOIDS ROOTS |
| DOI | 10.1080/10286020.2023.2289595 |
| Indexed By | SCI |
| WOS ID | WOS:001121612100001 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/75612 |
| Collection | 中国科学院昆明植物研究所 |
| Recommended Citation GB/T 7714 | Ren,Xue,Yuan,Xin,Chen,Yu-Ying,et al. New triterpenoids from the aerial parts of the Uygur medicine Salvia deserta[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2023. |
| APA | Ren,Xue.,Yuan,Xin.,Chen,Yu-Ying.,Zhang,Qiao-Zhuo.,Tan,Chun-Lin.,...&Li,Sheng-Hong.(2023).New triterpenoids from the aerial parts of the Uygur medicine Salvia deserta.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH. |
| MLA | Ren,Xue,et al."New triterpenoids from the aerial parts of the Uygur medicine Salvia deserta".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2023). |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| 1722405777_29406_37a（1675KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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