New triterpenoids from the aerial parts of the Uygur medicine Salvia deserta

doi:10.1080/10286020.2023.2289595

KIB OpenIR

	New triterpenoids from the aerial parts of the Uygur medicine Salvia deserta
	Ren,Xue; Yuan,Xin; Chen,Yu-Ying; Zhang,Qiao-Zhuo; Tan,Chun-Lin; Kang,Juan-Juan; Luo,Shi-Hong; Liu,Yan; Guo,Kai; Li,Sheng-Hong
	2023
发表期刊	JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
ISSN	1477-2213
摘要	Phytochemical investigation on the aerial parts of Salvia deserta led to the isolation of eight new pentacyclic triterpenoids including three oleanane- (1 - 3) and five ursane-type (4 - 8) triterpenoids, whose structures were elucidated based on extensive spectroscopic analysis and quantum chemical calculation. Weak immunosuppressive potency was observed for compounds 1, 2, and 4 - 8 via inhibiting the secretion of cytokines TNF-alpha and IL-6 in LPS-induced macrophages RAW264.7 at 20 mu M. In addition, compounds 1, 2, and 4 - 6 exhibited moderate protective activity on t-BHP-induced oxidative injury in HepG2 cells.
关键词	Lamiaceae Salvia deserta triterpenoids immunosuppressive activity hepatoprotective activity URSANE-TYPE TRITERPENES DITERPENOIDS ROOTS
DOI	10.1080/10286020.2023.2289595
收录类别	SCI
WOS记录号	WOS:001121612100001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75612
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Ren,Xue,Yuan,Xin,Chen,Yu-Ying,et al. New triterpenoids from the aerial parts of the Uygur medicine Salvia deserta[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2023.
APA	Ren,Xue.,Yuan,Xin.,Chen,Yu-Ying.,Zhang,Qiao-Zhuo.,Tan,Chun-Lin.,...&Li,Sheng-Hong.(2023).New triterpenoids from the aerial parts of the Uygur medicine Salvia deserta.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH.
MLA	Ren,Xue,et al."New triterpenoids from the aerial parts of the Uygur medicine Salvia deserta".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2023).

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