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Identification and Characterization of ShSPI, a Kazal-Type Elastase Inhibitor from the Venom of Scolopendra Hainanum 期刊论文
TOXINS, 2019, 卷号: 11, 期号: 12, 页码: 13
作者:  Luan, Ning;  Zhao, Qiyu;  Duan, Zilei;  Ji, Mengyao;  Xing, Meichen;  Zhu, Tengyu;  Mwangi, James;  Rong, Mingqiang;  Liu, Jiangxin;  Lai, Ren
浏览  |  Adobe PDF(2415Kb)  |  收藏  |  浏览/下载：229/42  |  提交时间：2020/03/18
centipede  kazal-type inhibitor  human neutrophils elastase  ShSPI  
Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
作者:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
浏览  |  Adobe PDF(1542Kb)  |  收藏  |  浏览/下载：339/84  |  提交时间：2020/03/18
delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
Structural determination of eleven new preschisanartane-type schinortriterpenoids from two Schisandra species and structural revision of preschisanartanin J using NMR computation method 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 970-981
作者:  Hu Kun;  Li Xing-Ren;  Tang Jian-Wei;  Li Xiao-Nian;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1250Kb)  |  收藏  |  浏览/下载：218/61  |  提交时间：2020/03/18
Schisandra sphaerandra  Schisandra rubriflora  Preschisanartane-type schinortriterpenoids  Structural revision  Quantum chemical calculation of NMR parameters  
Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors 期刊论文
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
作者:  Sajesh, Babu, V;  On, Ngoc H.;  Omar, Refaat;  Alrushaid, Samaa;  Kopec, Brian M.;  Wang, Wei-Guang;  Sun, Han-Dong;  Lillico, Ryan;  Lakowski, Ted M.;  Siahaan, Teruna J.;  Davies, Neal M.;  Puno, Pema-Tenzin;  Vanan, Magimairajan Issai;  Miller, Donald W.
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blood-brain barrier (BBB)  drug delivery  transient modulation  HAV6 cadherin peptide  adenanthin  magnetic resonance imaging (MRI)  medulloblastoma  
Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin 期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 8, 页码: 1122-+
作者:  Zhu, Huifang;  Wang, Bin;  Kong, Lingmei;  An, Tao;  Li, Gentao;  Zhou, Hongyu;  Gong, Liang;  Zhao, Zhangxun;  Gong, Yaxiao;  Sun, Handong;  Puno, Pematenzin;  Li, Yan
浏览  |  Adobe PDF(4600Kb)  |  收藏  |  浏览/下载：221/40  |  提交时间：2019/10/14
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
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Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Recombinant polyphenol oxidases for production of theaflavins from tea polyphenols 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 134, 页码: 139-145
作者:  Zeng, Jun;  Du, Gang;  Shao, Xue;  Feng, Ke-Na;  Zeng, Ying
浏览  |  Adobe PDF(1259Kb)  |  收藏  |  浏览/下载：202/59  |  提交时间：2019/08/19
Theaflavins  Recombinant polyphenol oxidase  Mesoporous silica  
Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
作者:  Chen, Si-Yue;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Yang, Xiao-Tong;  Su, Li-Hua;  He, Xiao-Feng;  Li, Tian-Ze;  Deng, Zhen-Tao;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1837Kb)  |  收藏  |  浏览/下载：230/42  |  提交时间：2019/09/10
Gastrodia elata  Polybenzyls  Melatonin receptors  Structure-activity relationships  Docking study  
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：269/74  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Whole-brain mapping of projection from mouse lateral septal nucleus 期刊论文
BIOLOGY OPEN, 2019, 卷号: 8, 期号: 7, 页码: 9
作者:  Deng, Ke;  Yang, Lu;  Xie, Jing;  Tang, He;  Wu, Gui-Sheng;  Luo, Huai-Rong
浏览  |  Adobe PDF(24131Kb)  |  收藏  |  浏览/下载：272/32  |  提交时间：2019/09/10
Lateral septal nucleus  H129  PRV  Neural circuits  Neural projection