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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  Favorite  |  View/Download：104/1  |  Submit date：2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
The compound BTB06584 is an IF1-dependent selective inhibitor of the mitochondrial F1Fo-ATPase1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-38
Authors:  Fabrice Ivanes;  Danilo Faccenda;  Jemma Gatliff;  Ahmed A Ahmed;  Stefania Cocco;  Carol Ho Ka Cheng;  Emma Allan;  Claire Russell;  Michael R Duchen;  Michelangelo Campanella
Adobe PDF(1228Kb)  |  Favorite  |  View/Download：23/1  |  Submit date：2017/07/24
Mitochondrial F1fo Atp Synthase  If1  Ischemia-induced Death  Btb06584  Pinotage  
Anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal through inhibition of STAT3 pathway 期刊论文
出版物, 3111, 期号: 0, 页码: 1-50
Authors:  Jung Ok Ban;  Dae Hwan Kim;  Hee Pom Lee;  Chul Ju Hwang;  Jung-Hyun Shim;  Dae Joong Kim;  Tae Myoung Kim;  Heon Sang Jeong;  Seong Su Nah;  Hanyong Chen;  Zigang Dong;  Young Wan Ham;  Youngsoo Kim;  Sang-Bae Han;  Jin Tae Hong
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Effector-triggered immunity by the plantpathogen Phytophthora 期刊论文
TRENDS in Microbiology, 3111, 卷号: 14, 期号: 11, 页码: 470-473
Authors:  Dinah Qutob;  Jennifer Tedman-Jones;  Mark Gijzen
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Total synthesis of dryocrassin ABBA and its analogues with potential inhibitory activity against drug-resistant neuraminidases 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 17, 页码: 3846-3852
Authors:  Hou, Bo;  Liu, Ze;  Yang, Xiao-Bei;  Zhu, Wen-Fei;  Li, Jin-Yu;  Yang, Liu;  Reng, Fu-Cai;  Lv, Yong-Feng;  Hu, Jiang-Miao;  Liao, Guo-Yang;  Zhou, Jun
Favorite  |  View/Download：3/0  |  Submit date：2019/09/10
Dryocrassin ABBA  Neuraminidase  Total synthesis  Shanghai H7N9  Anhui H7N9  
Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity 期刊论文
BMC Cancer, 2019, 卷号: 19, 期号: 1
Authors:  Wang,Ning;  Fan,Yanhua;  Yuan,Chun-Mao;  Song,Jialei;  Yao,Yao;  Liu,Wuling;  Gajendran,Babu;  Zacksenhaus,Eldad;  Li,Yanmei;  Liu,Jielin;  Hao,Xiao Jiang;  Ben-David,Yaacov
Favorite  |  View/Download：10/0  |  Submit date：2019/08/13
Cancer  Leukemia  Chinese medicinal plant  Melia azedarach  Drug screen  ERK1/2 agonists  Differentiation  Apoptosis  
Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
Authors:  Chen, Si-Yue;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Yang, Xiao-Tong;  Su, Li-Hua;  He, Xiao-Feng;  Li, Tian-Ze;  Deng, Zhen-Tao;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Gastrodia elata  Polybenzyls  Melatonin receptors  Structure-activity relationships  Docking study  
Design, Synthesis, and Biological Evaluation of Novel Biotinylated Podophyllotoxin Derivatives as Potential Antitumor Agents 期刊论文
FRONTIERS IN CHEMISTRY, 2019, 卷号: 7, 页码: 14
Authors:  Zi, Cheng-Ting;  Gao, Yin-Sheng;  Yang, Liu;  Feng, Shu-Yun;  Huang, Yue;  Sun, Li;  Jin, Yi;  Xu, Feng-Qing;  Dong, Fa-Wu;  Li, Yan;  Ding, Zhong-Tao;  Zhou, Jun;  Jiang, Zi-Hua;  Yuan, Sheng-Tao;  Hu, Jiang-Miao
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podophyllotoxin derivatives  biotin  anticancer activity  synthesis  apoptosis  
Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176
Authors:  Li, Yingying;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Liu, Xingyong;  Zhang, Li;  Wang, Liang-Liang;  Zuo, Zhili
Favorite  |  View/Download：11/0  |  Submit date：2019/07/29
Pharmacophore modeling  Molecular docking  Quantitative structure activity relationship (QSAR)  Molecular dynamics  AMPK  Activator  
Glycoside Hydrolase Family 39 beta-Xylosidases Exhibit beta-1,2-Xylosidase Activity for Transformation of Notoginsenosides: A New EC Subsubclass 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 11, 页码: 3220-3228
Authors:  Zhang, Rui;  Li, Na;  Xu, Shujing;  Han, Xiaowei;  Li, Chunyan;  Wei, Xin;  Liu, Yu;  Tu, Tao;  Tang, Xianghua;  Zhou, Junpei;  Huang, Zunxi
Favorite  |  View/Download：8/0  |  Submit date：2019/07/29
beta-xylosidase  beta-1,2-glycosidic bond  enzyme commission  notoginsenosides  glycoside hydrolase family 39