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Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
浏览  |  Adobe PDF(5724Kb)  |  收藏  |  浏览/下载:361/40  |  提交时间:2017/12/18
Synthesis of selective 11 beta-HSD1 inhibitors based on dammarane scaffold 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 135, 页码: 324-338
作者:  Shao, Li-Dong;  Bao, Ying;  Shen, Yu;  Su, Jia;  Leng, Ying;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1336Kb)  |  收藏  |  浏览/下载:287/66  |  提交时间:2017/07/31
11 Beta-hsd1 Inhibitor  Hupehenols  Dammarane  Sar  
Natural Product Vibsanin A Induces Differentiation of Myeloid Leukemia Cells through PKC Activation 期刊论文
CANCER RESEARCH, 2016, 卷号: 76, 期号: 9, 页码: 2698-2709
作者:  Yu, Zu-Yin;  Xiao, He;  Wang, Li-Mei;  Shen, Xing;  Jing, Yu;  Wang, Lin;  Sun, Wen-Feng;  Zhang, Yan-Feng;  Cui, Yu;  Shan, Ya-Jun;  Zhou, Wen-Bing;  Xing, Shuang;  Xiong, Guo-Lin;  Liu, Xiao-Lan;  Dong, Bo;  Feng, Jian-Nan;  Wang, Li-Sheng;  Luo, Qing-Liang;  Zhao, Qin-Shi;  Cong, Yu-Wen
浏览  |  Adobe PDF(1368Kb)  |  收藏  |  浏览/下载:269/94  |  提交时间:2016/08/22
Natural product vibsanine A induces differentiation of myeloid leukemia cells through PKC activation 期刊论文
Cancer Research, 2016, 期号: 1, 页码: 1
作者:  Zhao QS(赵勤实)
浏览  |  Adobe PDF(1368Kb)  |  收藏  |  浏览/下载:126/41  |  提交时间:2017/02/28
Huperserines A-E, Lycopodium alkaloids from Huperzia serrata 期刊论文
FITOTERAPIA, 2014, 卷号: 99, 页码: 72-77
作者:  Jiang, Wei-Wei;  Liu, Fei;  Gao, Xiu;  He, Juan;  Cheng, Xiao;  Peng, Li-Yan;  Wu, Xing-De;  Zhao, Qin-Shi
浏览  |  Adobe PDF(528Kb)  |  收藏  |  浏览/下载:186/61  |  提交时间:2015/06/17
Hupetzia Serrate  Lycopodium Alkaloids  Huperserines A-e  Anti-ache Activity  
Identification and validation of p50 as the cellular target of eriocalyxin B 期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 22, 页码: 11354-11364
作者:  Kong, Ling-Mei;  Deng, Xu;  Zuo, Zhi-Li;  Sun, Han-Dong;  Zhao, Qin-Shi;  Li, Yan
浏览  |  Adobe PDF(3014Kb)  |  收藏  |  浏览/下载:261/67  |  提交时间:2015/06/17
Erib  Activity-based Probes  P50  Nf-kappa b Signaling  Apoptosis  
Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor gamma synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells 期刊论文
CANCER LETTERS, 2009, 卷号: 275, 期号: 2, 页码: 247-255
作者:  Sun, Wei-Hao;  Chen, Guo-Sheng;  Ou, Xi-Long;  Yang, Ye;  Luo, Cheng;  Zhang, Yuan;  Shao, Yun;  Xu, Hai-Chen;  Xiao, Bin;  Xue, Yi-Ping;  Zhou, Su-Ming;  Zhao, Qin-Shi;  Ding, Guo-Xian
Adobe PDF(635Kb)  |  收藏  |  浏览/下载:1228/361  |  提交时间:2011/12/19
Pancreatic Cancer  Cyclooxygenase-2  Peroxisome Proliferators-activated Receptor  Gamma  Proliferation  Apoptosis  
Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro 期刊论文
CANCER LETTERS, 2008, 卷号: 263, 期号: 2, 页码: 302-311
作者:  Sun, Wei-Hao;  Zhu, Feng;  Chen, Guo-Sheng;  Su, Han;  Luo, Cheng;  Zhao, Qin-Shi;  Zhang, Yuan;  Shao, Yun;  Sun, Jian;  Zhou, Su-Ming;  Ding, Guo-Xian;  Cheng, Yun-Lin
Adobe PDF(809Kb)  |  收藏  |  浏览/下载:317/96  |  提交时间:2011/11/24
Cholecystokinin-2 Receptor  Cyclooxygenase-2  Mkn-45 Cell  Proliferation  Apoptosis