Structural determination of eleven new preschisanartane-type schinortriterpenoids from two Schisandra species and structural revision of preschisanartanin J using NMR computation method

	Structural determination of eleven new preschisanartane-type schinortriterpenoids from two Schisandra species and structural revision of preschisanartanin J using NMR computation method
	Hu Kun; Li Xing-Ren; Tang Jian-Wei; Li Xiao-Nian; Puno, Pema-Tenzin
通讯作者	Puno, Pema-Tenzin(punopematenzin@mail.kib.ac.cn)
	2019-12-01
发表期刊	CHINESE JOURNAL OF NATURAL MEDICINES
ISSN	2095-6975
卷号	17 期号:12 页码:970-981
摘要	Nineteen preschisanartane-type schinortriterpenoids (SNTs), among which eleven ones were previously undescribed, were isolated from two Schisandra species, S. sphaerandra and S. rubriflora. Their structures were determined using 1D and 2D NMR spectroscopic analyses, NMR data comparison, quantum chemical calculation of NMR parameters, electronic circular dichroism (ECD), X-ray single crystal diffraction, and chemical derivation. Furthermore, structural re-examination of a few previously reported preschisanartane-type SNTs led to the structural revision of preschisanartanin J. Besides, it is suggested that the reported structures of arisanlactone D and schilancidilactone W should be re-checked. Finally, a few isolated SNTs were found to possess neurite outgrowth-promoting activities, and protective activities against neural injuries.
关键词	Schisandra sphaerandra Schisandra rubriflora Preschisanartane-type schinortriterpenoids Structural revision Quantum chemical calculation of NMR parameters
收录类别	SCI ; SCI
语种	英语
WOS记录号	WOS:000504330400015
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/70547
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Puno, Pema-Tenzin
作者单位	Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
推荐引用方式 GB/T 7714	Hu Kun,Li Xing-Ren,Tang Jian-Wei,et al. Structural determination of eleven new preschisanartane-type schinortriterpenoids from two Schisandra species and structural revision of preschisanartanin J using NMR computation method[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2019,17(12):970-981.
APA	Hu Kun,Li Xing-Ren,Tang Jian-Wei,Li Xiao-Nian,&Puno, Pema-Tenzin.(2019).Structural determination of eleven new preschisanartane-type schinortriterpenoids from two Schisandra species and structural revision of preschisanartanin J using NMR computation method.CHINESE JOURNAL OF NATURAL MEDICINES,17(12),970-981.
MLA	Hu Kun,et al."Structural determination of eleven new preschisanartane-type schinortriterpenoids from two Schisandra species and structural revision of preschisanartanin J using NMR computation method".CHINESE JOURNAL OF NATURAL MEDICINES 17.12(2019):970-981.

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