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Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
Authors:  Chen, Si-Yue;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Yang, Xiao-Tong;  Su, Li-Hua;  He, Xiao-Feng;  Li, Tian-Ze;  Deng, Zhen-Tao;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
Favorite  |  View/Download:5/0  |  Submit date:2019/09/10
Gastrodia elata  Polybenzyls  Melatonin receptors  Structure-activity relationships  Docking study  
Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 39-46
Authors:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
Favorite  |  View/Download:27/0  |  Submit date:2019/06/24
Uncaria rhynchophylla  Catechin  Melatonin receptors  Metabolites  Antidepressant activity  
Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 期号: 0, 页码: 381-393
Authors:  Yang, Tong-Hua;  Ma, Yun-Bao;  Geng, Chang-An;  Yan, De-Xiu;  Huang, Xiao-Yan;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
View  |  Adobe PDF(2088Kb)  |  Favorite  |  View/Download:59/12  |  Submit date:2018/10/04
Depression  Magnolol Derivatives  Mt1/2 Receptors  Metabolites  Monoamine Neurotransmitter  
Dereplication-guided isolation of a new indole alkaloid triglycoside from the hooks of Uncaria rhynchophylla by LC with ion trap time-of-flight MS 期刊论文
JOURNAL OF SEPARATION SCIENCE, 2018, 卷号: 41, 期号: 7, 页码: 1532-1538
Authors:  Zhang, Jian-Gang;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Geng, Chang-An
View  |  Adobe PDF(1155Kb)  |  Favorite  |  View/Download:65/12  |  Submit date:2018/05/08
5-hydroxytryptamine Receptors  Dereplication-guided Isolation  Indole Alkaloid Triglycoside  Melatonin Receptors  Traditional Chinese Medicine  
Dereplication-guided isolation of a new indole alkaloid triglycoside from the hooks of Uncaria rhynchophylla by LC with ion trap time-of-flight MS 期刊论文
J Sep Sci, 2018, 卷号: 41, 期号: 0, 页码: 1532–1538.
Authors:  Jian-Gang Zhang;  Xiao-Yan Huang;  un-Bao Ma;  ue-Mei Zhang;  Ji-Jun Chen;  Chang-An Geng
View  |  Adobe PDF(595Kb)  |  Favorite  |  View/Download:20/11  |  Submit date:2019/03/25
Metabolic map of osthole and its effect on lipids 期刊论文
XENOBIOTICA, 2018, 卷号: 48, 期号: 3, 页码: 285-299
Authors:  Zhao, Qi;  Li, Xin-Mei;  Liu, Hong-Ning;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(2482Kb)  |  Favorite  |  View/Download:139/23  |  Submit date:2017/11/17
Lipid  Metabolomics  Metabolic Disease  Osthole  Time-of-flight Mass Spectrometry  Ultra-performance Liquid Chromatography  
老药新用:奥柳氮钠的降尿酸作用及分子机制研究 学位论文
: 中国科学院大学, 2017
Authors:  牛艳芬
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Potential role of CYP1B1 in the development and treatment of metabolic diseases 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2017, 卷号: 178, 页码: 18-30
Authors:  Li, Fei;  Zhu, Weifeng;  Gonzalez, Frank J.
View  |  Adobe PDF(2083Kb)  |  Favorite  |  View/Download:61/11  |  Submit date:2017/11/20
Cyp1b1  Metabolic Diseases  Metabolic Pathways  Metabolomics  
钩藤化学成分与生物活性比较 学位论文
: 中国科学院大学, 2017
Authors:  张建钢
Adobe PDF(6730Kb)  |  Favorite  |  View/Download:25/1  |  Submit date:2019/06/14
托品烷、芦竹碱和百里酚衍生物的合成及生物活性研究 学位论文
: 中国科学院大学, 2017
Authors:  尹秀娟
Adobe PDF(6718Kb)  |  Favorite  |  View/Download:8/0  |  Submit date:2019/06/14