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Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel 期刊论文
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
作者:  Hu,Guilin;  Dong,Ding;  Du,Shuzong;  Peng,Xingrong;  Wu,Mingkun;  Shi,Qiangqiang;  Hu,Kun;  Hong,Defu;  Wang,Xiaoyuan;  Zhou,Lin;  Nian,Yin;  Qiu,Minghua
Adobe PDF(4722Kb)  |  收藏  |  浏览/下载：146/40  |  提交时间：2022/04/02
Coffea arabica L  Roasted coffee  Coffee diterpenoid  Cafestol  Kahweol  T-type Ca2+ channels  Ca(v)3.1 low voltage-gated Ca2+ channel  Ca(v)3.1 inhibitors  CALCIUM-CHANNELS  CAFESTOL  KAHWEOL  PHYSIOLOGY  ESTERS  NOMENCLATURE  PHARMACOLOGY  APOPTOSIS  FURANS  
Monoterpene Indole Alkaloids with Ca(v)3.1 T-Type Calcium Channel Inhibitory Activity from Catharanthus roseus 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 21, 页码: 6516
作者:  Deng,Zhen-Tao;  Li,Wen-Yan;  Wang,Lei;  Zhou,Zhi-Ping;  Wu,Xing-De;  Ding,Zhong-Tao;  Zhao,Qin-Shi
Adobe PDF(2354Kb)  |  收藏  |  浏览/下载：115/57  |  提交时间：2022/04/02
Catharanthus roseus  monoterpene indole alkaloid  catharanosine A  Ca(v)3  1 low voltage-gated calcium channel (LVGCC)  VINCA ALKALOIDS  CELL-PROLIFERATION  N-OXIDE  SARPAGINE  BIOSYNTHESIS  VINORELBINE  VINBLASTINE  MECHANISM  ROOTS  BASES  
Discovery of novel modulators targeting human TRPC5: Docking-based virtual screening, molecular dynamics simulation and binding af fi nity predication 期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2021, 卷号: 102, 页码: 107795
作者:  Liu,Bin;  Zhang,Wei;  Guo,Sheng;  Zuo,Zhili
浏览  |  Adobe PDF(4277Kb)  |  收藏  |  浏览/下载：73/10  |  提交时间：2022/04/02
hTRPC5  Homology modeling  Molecular docking  Molecular dynamics simulation  Virtual screening  INHIBITOR  CHANNELS  GROMACS  POTENT  AMBER  IDENTIFICATION  CONSTRAINTS  INTEGRATION  AMYGDALA  
Rhynchines A-E: Ca(v)3.1 Calcium Channel Blockers from Uncaria rhynchophylla 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 24, 页码: 9463-9467
作者:  Zhou,Hao-Feng;  Li,Wen-Yan;  Peng,Li-Yan;  Li,Xiao-Nian;  Zuo,Zhi-Li;  Zhao,Qin-Shi
浏览  |  Adobe PDF(2313Kb)  |  收藏  |  浏览/下载：82/35  |  提交时间：2022/04/02
INDOLE ALKALOIDS  
Applanmerotic acids A and B, two meroterpenoid dimers with an unprecedented polycyclic skeleton from Ganoderma applanatum that inhibit formyl peptide receptor 2 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2021, 卷号: 8, 期号: 13, 页码: 3381-3389
作者:  Peng,Xingrong;  Su,Haiguo;  Wang,Huirong;  Hu,Guilin;  Hu,Kun;  Zhou,Lin;  Qiu,Minghua
Adobe PDF(2304Kb)  |  收藏  |  浏览/下载：119/22  |  提交时间：2022/04/02
Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans 期刊论文
CELL CALCIUM, 2021, 卷号: 93, 页码: 102327
作者:  Yang,Zhong-Lin;  Chen,Jian-Ning;  Lu,Yu-Yang;  Lu,Min;  Wan,Qin-Li;  Wu,Gui-Sheng;  Luo,Huai-Rong
Adobe PDF(4473Kb)  |  收藏  |  浏览/下载：80/23  |  提交时间：2022/04/02
Inositol polyphosphates  Inositol polyphosphate multikinase  Type I inositol 5-phosphatase  Development  Calcium signaling  Defecation rhythm  C. elegans  C-ELEGANS  PHOSPHOLIPASE-C  CALCIUM  1,4,5-TRISPHOSPHATE  CALCINEURIN  KINASE  IDENTIFICATION  TRISPHOSPHATE  METABOLISM  RECEPTOR  
Novel Meroterpenoids from Hypericum patulum: Highly Potent Late Na(v)1.5 Sodium Current Inhibitors 期刊论文
ORGANIC LETTERS, 2020
作者:  Ye, Yan-Song;  Du, Shu-Zong;  Jiang, Na-Na;  Xu, Hong-Xi;  Yang, Jian;  Fu, Wen-Wei;  Nian, Yin;  Xu, Gang
Adobe PDF(1634Kb)  |  收藏  |  浏览/下载：166/34  |  提交时间：2021/01/05
Congenetic Hybrids Derived from Dearomatized Isoprenylated Acylphloroglucinol with Opposite Effects on Ca(v)3.1 Low Voltage Gated Ca2+ Channel 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020
作者:  Ye, Yan-Song;  Li, Wen-Yan;  Du, Shu-Zong;  Yang, Jian;  Nian, Yin;  Xu, Gang
Adobe PDF(2605Kb)  |  收藏  |  浏览/下载：124/31  |  提交时间：2021/01/05
Hyphenone A, the first 3,3-diisoprenylated bicyclic polyprenylated acylphloroglucinols as Ca(v)3.1 T-type calcium channel inhibitor from Hypericum henryi 期刊论文
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 45, 页码: 5
作者:  Jiang, Na-Na;  Du, Shu-Zong;  Ye, Yan-Song;  Yan, Hui;  Yang, Xing-Wei;  Yang, Jian;  Nian, Yin;  Xu, Gang
浏览  |  Adobe PDF(872Kb)  |  收藏  |  浏览/下载：125/22  |  提交时间：2020/03/17
Polyprenylated acylphloroglucinol  Hyphenone A  Hypericum henryi  Ca(v)3.1 T-type calcium channel  
Ergosterols from Ganoderma sinense and their anti-inflammatory activities by inhibiting NO production 期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 32, 页码: 177-180
作者:  Mei, Ren-Qiang;  Zuo, Feng-Jiao;  Duan, Xiao-Yan;  Wang, Yi-Na;  Li, Jun-Rong;  Qian, Cheng-Zhen;  Xiao, Ji-Ping
浏览  |  Adobe PDF(1200Kb)  |  收藏  |  浏览/下载：162/31  |  提交时间：2019/09/10
Ganoderma sinense  Ergosterol  NO production inhibition