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Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
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Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata 期刊论文
PHYTOCHEMISTRY LETTERS, 2016, 卷号: 18, 期号: 1, 页码: 176-179
作者:  Yuan, Wen-Juan;  Yang, Guo-Ping;  Zhang, Jia-Hui;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Di, Ying-Tong;  Hao, Xiao-Jiang
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Euphorbiaceae  Euphorbia Ebracteolata  Diterpenes  Ebracteolatas A-c  Cytotoxic Activity  
CDDO-Me reveals USP7 as a novel target in ovarian cancer cells 期刊论文
Oncotarget, 2016, 卷号: 7, 期号: 47, 页码: 77096-77109
作者:  Qin, Dongjun;  Wang, Weiwei;  Lei, Hu;  Luo, Hao;  Cai, Haiyan;  Tang, Caixia;  Wu, Yunzhao;  Wang, Yingying;  Jin, Jin;  Xiao, Weilie;  Wang, Tongdan;  Ma, Chunmin;  Xu, Hanzhang;  Zhang, Jinfu;  Gao, Fenghou;  Wu, Ying-Li
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Cddo-me  Ovarian Cancer  Usp7  Cetsa  Deubiquitinating Enzymes  
16-nor Limonoids from Harrisonia perforata as promising selective 11 beta-HSD1 inhibitors 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 页码: 1
作者:  Xiao-HuiYan;  Yi, Ping;  Cao, Pei;  Yang, Shi-Ying;  Fang, Xin;  Zhang, Yu;  Wu, Bin;  Leng, Ying;  Di, Ying-Tong;  Lv, Yang;  Hao, Xiao-Jiang
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RACK1 is required for adipogenesis 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2016, 卷号: 311, 期号: 5, 页码: C831-C836
作者:  Kong, Qinghua;  Gao, Lan;  Niu, Yanfen;  Gongpan, Pianchou;  Xu, Yuhui;  Li, Yan;  Xiong, Wenyong
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Rack1  3t3-l1  Adipogenesis  Wnt  Pi3k-akt-mtor-s6k  
Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 66689-66699
作者:  Zhang, Ruowen;  Che, Xun;  Zhang, Jingjie;  Li, Yang;  Li, Jingxia;  Deng, Xu;  Zhu, Junlan;  Jin, Honglei;  Zhao, Qinshi;  Huang, Chuanshu
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Chel a  Human Bladder Cancer  Apoptosis  Phlpp2  C-jun  
Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids 期刊论文
NATURE COMMUNICATIONS, 2016, 卷号: 7, 期号: 1, 页码: 1
作者:  Yan, Yijun;  Yang, Jing;  Yu, Zhiyin;  Yu, Mingming;  Ma, Ya-Tuan;  Wang, Li;  Su, Can;  Luo, Jianying;  Horsman, Geoffrey P.;  Huang, Sheng-Xiong
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Functional Genome Mining for Metabolites Encoded by Large Gene Clusters through Heterologous Expression of a Whole-Genome Bacterial Artificial Chromosome Library in Streptomyces spp. 期刊论文
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2016, 卷号: 82, 期号: 19, 页码: 5795-5805
作者:  Xu, Min;  Wang, Yemin;  Zhao, Zhilong;  Gao, Guixi;  Huang, Sheng-Xiong;  Kang, Qianjin;  He, Xinyi;  Lin, Shuangjun;  Pang, Xiuhua;  Deng, Zixin;  Tao, Meifeng
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Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 116, 页码: 39-50
作者:  Zhou, Hongyu;  Shang, Chaowei;  Wang, Min;  Shen, Tao;  Kong, Lingmei;  Yu, Chunlei;  Ye, Zhennan;  Luo, Yan;  Liu, Lei;  Li, Yan;  Huang, Shile
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Ciclopirox  Mtor  Ampk  Tsc2  Raptor  
Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 37, 页码: 58995-59005
作者:  Wu, Jingjing;  Lei, Hu;  Zhang, Jinfu;  Chen, Xiangyun;  Tang, Caixia;  Wang, Weiwei;  Xu, Hanzhang;  Xiao, Weilie;  Gu, Wenli;  Wu, Yingli
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Momordin Ic  Senp1  Sumoylation  Proliferation  Prostate Cancer