Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata
Yuan, Wen-Juan1,2; Yang, Guo-Ping4; Zhang, Jia-Hui3; Zhang, Yu3; Chen, Duo-Zhi3; Li, Shun-Lin3; Di, Ying-Tong3; Hao, Xiao-Jiang1
2016-12-01
发表期刊PHYTOCHEMISTRY LETTERS
卷号18期号:1页码:176-179
摘要From the roots of Euphorbia ebracteolata Hayata, three new diterpenes, Ebracteolatas A-C, based on the rosane (1-2) and lathyrane (3) skeleton, were isolated together with four known ones (4-7). Their structures and relative configurations were elucidated on the basis of spectroscopic methods, especially 2D NMR techniques. Compounds 1, 6, and 7 exhibited moderate cytotoxic effects against five cancer cell lines. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.
关键词Euphorbiaceae Euphorbia Ebracteolata Diterpenes Ebracteolatas A-c Cytotoxic Activity
资助信息National Science Foundation of China(21432010; Technological leading talent project of Yunnan(2015HA020); Central Asian Drug Discovery and Development Center of Chinese Academy of Sciences(CAM201402; Science Foundation of Yunnan(2014A050); Young Academic and Technical Leader Foundation of Yunnan Province; Xibuzhiguang Project; 21372228); CAM201302)
DOI10.1016/j.phytol.2016.10.008
收录类别SCI
语种英语
WOS研究方向Plant Sciences ; Oncology
WOS类目Plant Sciences ; Oncology
WOS记录号WOS:000389521800034
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被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.kib.ac.cn/handle/151853/33780
专题植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Urumqi 830011, Xinjiang, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
4.Yunnan Agr Univ, Kunming 650201, Yunnan, Peoples R China
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Yuan, Wen-Juan,Yang, Guo-Ping,Zhang, Jia-Hui,et al. Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata[J]. PHYTOCHEMISTRY LETTERS,2016,18(1):176-179.
APA Yuan, Wen-Juan.,Yang, Guo-Ping.,Zhang, Jia-Hui.,Zhang, Yu.,Chen, Duo-Zhi.,...&Hao, Xiao-Jiang.(2016).Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata.PHYTOCHEMISTRY LETTERS,18(1),176-179.
MLA Yuan, Wen-Juan,et al."Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata".PHYTOCHEMISTRY LETTERS 18.1(2016):176-179.
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