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YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
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Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
RUNX1-Regulated Signaling Pathways in Ovarian Cancer 期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
Authors:  Chen,Yuanzhi;  He,Yingying;  Liu,Shubai
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Runt-related transcription factor 1 (RUNX1)  ovarian cancer  apoptosis  signaling pathways  clinical therapeutic target  GROWTH-FACTOR  TRANSCRIPTION FACTORS  STEM-CELLS  RUNX1  STAT3  FAMILY  ACTIVATION  APOPTOSIS  LEUKEMIA  SURVIVAL  
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 886
Authors:  Chen,Yuanzhi;  He,Zhicheng;  Yang,Shuting;  Chen,Cheng;  Xiong,Wenyong;  He,Yingying;  Liu,Shubai
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Runt-related transcription factor 1 (RUNX1)  High-grade serous ovarian carcinoma (HGSOC)  Apoptosis  EMT  Clinical therapeutic target  EPITHELIAL-MESENCHYMAL TRANSITIONS  HEPATOCELLULAR-CARCINOMA  TRANSCRIPTION FACTOR  TP53 MUTATIONS  UP-REGULATION  TUMOR-GROWTH  MIGRATION  PROLIFERATION  INVASION  FOXO1  
四种高含量天然产物的化学及生物功能研究 学位论文
, 2021
Authors:  周元飞
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Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
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Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
Authors:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
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Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID  
CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell 期刊论文
ONCOGENESIS, 2021, 卷号: 10, 期号: 7, 页码: 49
Authors:  He,YingYing;  He,Zhicheng;  Lin,Jian;  Chen,Cheng;  Chen,Yuanzhi;  Liu,Shubai
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BINDING-PROTEIN CTBP  TRANSCRIPTIONAL COREPRESSOR  NEGATIVE MODULATION  PROMOTES APOPTOSIS  GENE-EXPRESSION  DAMAGE RESPONSE  PK  OVEREXPRESSION  PHOSPHOPROTEIN  TRANSFORMATION  
Platelet-activating factor acetyl hydrolase IB2 dysregulated cell proliferation in ovarian cancer 期刊论文
CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 697
Authors:  He,YingYing;  He,Zhicheng;  Zhang,Xiaoyu;  Liu,Shubai
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Ovarian cancer  Ester lipid  Tyrosine kinase signaling pathway  Platelet-activating factor  FACTOR-ACETYLHYDROLASE ACTIVITY  LYSOPHOSPHATIDIC ACID  FACTOR RECEPTOR  EMERGING ROLE  EXPRESSION  GROWTH  PAF  MECHANISMS  PAFAH1B3  SUBUNIT  
Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans 期刊论文
CELL CALCIUM, 2021, 卷号: 93, 页码: 102327
Authors:  Yang,Zhong-Lin;  Chen,Jian-Ning;  Lu,Yu-Yang;  Lu,Min;  Wan,Qin-Li;  Wu,Gui-Sheng;  Luo,Huai-Rong
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Inositol polyphosphates  Inositol polyphosphate multikinase  Type I inositol 5-phosphatase  Development  Calcium signaling  Defecation rhythm  C. elegans  C-ELEGANS  PHOSPHOLIPASE-C  CALCIUM  1,4,5-TRISPHOSPHATE  CALCINEURIN  KINASE  IDENTIFICATION  TRISPHOSPHATE  METABOLISM  RECEPTOR  
岩藻糖化糖胺聚糖的寡糖结构及其抗乙酰肝素酶活性研究 学位论文
, 2020
Authors:  周路坦
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