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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK
期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:
Ling-Chu Chang
;
Hui-Yi Lin
;
Meng-Tung Tsai
;
Ruey-Hwang Chou
;
Fang-Yu Lee
;
Che-Ming Teng
;
Min-Tsang Hsieh
;
Hsin-Yi Hung
;
Li-Jiau Huang
;
Yung-Luen Yu
;
Sheng-Chu Kuo
Adobe PDF(1357Kb)
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Submit date:2017/07/24
Yc-1
Triple-negative Breast Cancer
Erk
Ezh2
C-cbl
RUNX1-Regulated Signaling Pathways in Ovarian Cancer
期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
Authors:
Chen,Yuanzhi
;
He,Yingying
;
Liu,Shubai
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Submit date:2024/05/09
Runt-related transcription factor 1 (RUNX1)
ovarian cancer
apoptosis
signaling pathways
clinical therapeutic target
GROWTH-FACTOR
TRANSCRIPTION FACTORS
STEM-CELLS
RUNX1
STAT3
FAMILY
ACTIVATION
APOPTOSIS
LEUKEMIA
SURVIVAL
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells
期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 886
Authors:
Chen,Yuanzhi
;
He,Zhicheng
;
Yang,Shuting
;
Chen,Cheng
;
Xiong,Wenyong
;
He,Yingying
;
Liu,Shubai
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Submit date:2024/05/09
Runt-related transcription factor 1 (RUNX1)
High-grade serous ovarian carcinoma (HGSOC)
Apoptosis
EMT
Clinical therapeutic target
EPITHELIAL-MESENCHYMAL TRANSITIONS
HEPATOCELLULAR-CARCINOMA
TRANSCRIPTION FACTOR
TP53 MUTATIONS
UP-REGULATION
TUMOR-GROWTH
MIGRATION
PROLIFERATION
INVASION
FOXO1
四种高含量天然产物的化学及生物功能研究
学位论文
, 2021
Authors:
周元飞
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Submit date:2024/03/20
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:
Zhu,Yan-Yan
;
Jin,Qiong
;
Chen,Shan-Shan
;
Jin,Dan-Ni
;
Wang,Zhao-Jie
;
He,Ying-Jie
;
Chen,Hui-Cheng
;
Zhao,Yun-Li
;
Zhao,Li-Xing
;
Dai,Zhi
;
Luo,Xiao-Dong
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Submit date:2022/04/02
Neothalfine
Bisbenzylisoquinoline alkaloid
Metastatic colorectal cancer
Metabolomic
Mitochondrial apoptosis
SMALL MOLECULES
IRINOTECAN
RESISTANCE
CELL
IMMUNOTHERAPY
OPPORTUNITIES
CHEMOTHERAPY
VINORELBINE
ALKALOIDS
PATHWAY
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
Authors:
Munikishore,Rachakunta
;
Wang,Liang-Liang
;
Zhang,Shuqun
;
Zhao,Qin-Shi
;
Zuo,Zhili
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Submit date:2022/04/02
Cathepsin L
small-molecule inhibitor
gram-scale synthesis
KGP94
cancer
FUNCTIONALIZED BENZOPHENONE
BIOLOGICAL EVALUATION
TUMOR PROGRESSION
CELL INVASION
EXPRESSION
ANALOGS
SUPPRESSION
DERIVATIVES
ACID
CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell
期刊论文
ONCOGENESIS, 2021, 卷号: 10, 期号: 7, 页码: 49
Authors:
He,YingYing
;
He,Zhicheng
;
Lin,Jian
;
Chen,Cheng
;
Chen,Yuanzhi
;
Liu,Shubai
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Submit date:2022/04/02
BINDING-PROTEIN CTBP
TRANSCRIPTIONAL COREPRESSOR
NEGATIVE MODULATION
PROMOTES APOPTOSIS
GENE-EXPRESSION
DAMAGE RESPONSE
PK
OVEREXPRESSION
PHOSPHOPROTEIN
TRANSFORMATION
Platelet-activating factor acetyl hydrolase IB2 dysregulated cell proliferation in ovarian cancer
期刊论文
CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 697
Authors:
He,YingYing
;
He,Zhicheng
;
Zhang,Xiaoyu
;
Liu,Shubai
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Submit date:2022/04/02
Ovarian cancer
Ester lipid
Tyrosine kinase signaling pathway
Platelet-activating factor
FACTOR-ACETYLHYDROLASE ACTIVITY
LYSOPHOSPHATIDIC ACID
FACTOR RECEPTOR
EMERGING ROLE
EXPRESSION
GROWTH
PAF
MECHANISMS
PAFAH1B3
SUBUNIT
Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans
期刊论文
CELL CALCIUM, 2021, 卷号: 93, 页码: 102327
Authors:
Yang,Zhong-Lin
;
Chen,Jian-Ning
;
Lu,Yu-Yang
;
Lu,Min
;
Wan,Qin-Li
;
Wu,Gui-Sheng
;
Luo,Huai-Rong
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Submit date:2022/04/02
Inositol polyphosphates
Inositol polyphosphate multikinase
Type I inositol 5-phosphatase
Development
Calcium signaling
Defecation rhythm
C. elegans
C-ELEGANS
PHOSPHOLIPASE-C
CALCIUM
1,4,5-TRISPHOSPHATE
CALCINEURIN
KINASE
IDENTIFICATION
TRISPHOSPHATE
METABOLISM
RECEPTOR
岩藻糖化糖胺聚糖的寡糖结构及其抗乙酰肝素酶活性研究
学位论文
, 2020
Authors:
周路坦
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Submit date:2023/11/02