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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK
期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:
Ling-Chu Chang
;
Hui-Yi Lin
;
Meng-Tung Tsai
;
Ruey-Hwang Chou
;
Fang-Yu Lee
;
Che-Ming Teng
;
Min-Tsang Hsieh
;
Hsin-Yi Hung
;
Li-Jiau Huang
;
Yung-Luen Yu
;
Sheng-Chu Kuo
Adobe PDF(1357Kb)
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Submit date:2017/07/24
Yc-1
Triple-negative Breast Cancer
Erk
Ezh2
C-cbl
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:
Zhu,Yan-Yan
;
Jin,Qiong
;
Chen,Shan-Shan
;
Jin,Dan-Ni
;
Wang,Zhao-Jie
;
He,Ying-Jie
;
Chen,Hui-Cheng
;
Zhao,Yun-Li
;
Zhao,Li-Xing
;
Dai,Zhi
;
Luo,Xiao-Dong
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Submit date:2022/04/02
Neothalfine
Bisbenzylisoquinoline alkaloid
Metastatic colorectal cancer
Metabolomic
Mitochondrial apoptosis
SMALL MOLECULES
IRINOTECAN
RESISTANCE
CELL
IMMUNOTHERAPY
OPPORTUNITIES
CHEMOTHERAPY
VINORELBINE
ALKALOIDS
PATHWAY
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
Authors:
Munikishore,Rachakunta
;
Wang,Liang-Liang
;
Zhang,Shuqun
;
Zhao,Qin-Shi
;
Zuo,Zhili
Adobe PDF(523Kb)
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Submit date:2022/04/02
Cathepsin L
small-molecule inhibitor
gram-scale synthesis
KGP94
cancer
FUNCTIONALIZED BENZOPHENONE
BIOLOGICAL EVALUATION
TUMOR PROGRESSION
CELL INVASION
EXPRESSION
ANALOGS
SUPPRESSION
DERIVATIVES
ACID
CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell
期刊论文
ONCOGENESIS, 2021, 卷号: 10, 期号: 7, 页码: 49
Authors:
He,YingYing
;
He,Zhicheng
;
Lin,Jian
;
Chen,Cheng
;
Chen,Yuanzhi
;
Liu,Shubai
Adobe PDF(3008Kb)
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Submit date:2022/04/02
BINDING-PROTEIN CTBP
TRANSCRIPTIONAL COREPRESSOR
NEGATIVE MODULATION
PROMOTES APOPTOSIS
GENE-EXPRESSION
DAMAGE RESPONSE
PK
OVEREXPRESSION
PHOSPHOPROTEIN
TRANSFORMATION
Platelet-activating factor acetyl hydrolase IB2 dysregulated cell proliferation in ovarian cancer
期刊论文
CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 697
Authors:
He,YingYing
;
He,Zhicheng
;
Zhang,Xiaoyu
;
Liu,Shubai
Adobe PDF(2666Kb)
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Submit date:2022/04/02
Ovarian cancer
Ester lipid
Tyrosine kinase signaling pathway
Platelet-activating factor
FACTOR-ACETYLHYDROLASE ACTIVITY
LYSOPHOSPHATIDIC ACID
FACTOR RECEPTOR
EMERGING ROLE
EXPRESSION
GROWTH
PAF
MECHANISMS
PAFAH1B3
SUBUNIT
Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans
期刊论文
CELL CALCIUM, 2021, 卷号: 93, 页码: 102327
Authors:
Yang,Zhong-Lin
;
Chen,Jian-Ning
;
Lu,Yu-Yang
;
Lu,Min
;
Wan,Qin-Li
;
Wu,Gui-Sheng
;
Luo,Huai-Rong
Adobe PDF(4473Kb)
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Submit date:2022/04/02
Inositol polyphosphates
Inositol polyphosphate multikinase
Type I inositol 5-phosphatase
Development
Calcium signaling
Defecation rhythm
C. elegans
C-ELEGANS
PHOSPHOLIPASE-C
CALCIUM
1,4,5-TRISPHOSPHATE
CALCINEURIN
KINASE
IDENTIFICATION
TRISPHOSPHATE
METABOLISM
RECEPTOR
Synthesis and antitumor activity of camptothecin-4 beta-triazolopodophyllotoxin conjugates
期刊论文
NATURAL PRODUCT RESEARCH, 2020
Authors:
Zi, Cheng-Ting
;
Yang, Liu
;
Dong, Fa-Wu
;
Kong, Qing-Hua
;
Ding, Zhong-Tao
;
Zhou, Jun
;
Jiang, Zi-Hua
;
Hu, Jiang-Miao
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Submit date:2021/01/05
Vasorelaxant 4,5-seco-abietane diterpenoids with diverse 6/6/6, 6/6/7, and 6/6/8 architectures from Salvia prattii Hemsl.
期刊论文
FITOTERAPIA, 2020
Authors:
Xia, Fan
;
Luo, Dan
;
Wang, Tingting
;
Ji, Xu
;
Xu, Gang
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Submit date:2021/01/05
NaKTI2, a Kunitz trypsin inhibitor transcriptionally regulated by NaWRKY3 and NaWRKY6, is required for herbivore resistance inNicotiana attenuata
期刊论文
PLANT CELL REPORTS, 2020
Authors:
Yin, Min
;
Song, Na
;
Chen, Suiyun
;
Wu, Jinsong
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Submit date:2021/01/05
Artemyrianolides A-S, Cytotoxic Sesquiterpenoids from Artemisia myriantha
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020
Authors:
Tang, Shuang
;
Zhang, Xin-Tian
;
Ma, Yun-Bao
;
Huang, Xiao-Yan
;
Geng, Chang-An
;
Li, Tian-Ze
;
Zhang, Xue-Mei
;
Shen, Cheng
;
Su, Li-Hua
;
Gao, Zhen
;
Chen, Ji-Jun
Adobe PDF(2674Kb)
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Submit date:2021/01/05