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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：146/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
浏览  |  Adobe PDF(2215Kb)  |  收藏  |  浏览/下载：174/50  |  提交时间：2020/03/18
Homology modeling and 3D-QSAR study of benzhydrylpiperazine delta opioid receptor agonists 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 83, 页码: 9
作者:  Pan, Chenling;  Meng, Hao;  Zhang, Shuqun;  Zuo, Zhili;  Shen, Yuehai;  Wang, Liangliang;  Chang, Kwen-Jen
浏览  |  Adobe PDF(1542Kb)  |  收藏  |  浏览/下载：231/73  |  提交时间：2020/03/18
delta opioid receptor agonists  3D-QSAR  Homology modeling  Molecular dynamics simulation  Molecular docking  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：164/28  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Flavipesines A and B and Asperchalasines E-H: Cytochalasans and Merocytochalasans from Aspergillus flavipes 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 11, 页码: 2994-3001
作者:  Zhang, Xiaotian;  Yang, Lu;  Wang, Wenjing;  Wu, Zhaodi;  Wang, Jianping;  Sun, Weiguang;  Li, Xiao-Nian;  Chen, Chunmei;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1885Kb)  |  收藏  |  浏览/下载：108/22  |  提交时间：2020/03/18
Alkaloids isolated from Tabemaemontana bufalina display xanthine oxidase inhibitory activity 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 166, 页码: 8
作者:  Shi, Bao-Bao;  Chen, Jing;  Bao, Mei-Fen;  Zeng, Ying;  Cai, Xiang-Hai
浏览  |  Adobe PDF(956Kb)  |  收藏  |  浏览/下载：203/70  |  提交时间：2019/10/28
Tabernaemontana bufalina apocynaceae  Alkaloid  Taberhaines A-D  Apparicine  Xanthine oxidase inhibitor  
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：180/37  |  提交时间：2020/03/26
Canescones A-E: aromatic polyketide dimers with PTP1B inhibitory activity from Penicillium canescens 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 18, 页码: 3274-3281
作者:  Zang, Yi;  Gong, Yi-Hua;  Li, Xu-Wen;  Li, Xiao-Nian;  Liu, Jun-Jun;  Chen, Chun-Mei;  Zhou, Yuan;  Gu, Liang-Hu;  Luo, Zeng-Wei;  Wang, Jian-Ping;  Sun, Wei-Guang;  Zhu, Hu-Cheng;  Zhang, Yong-Hui
浏览  |  Adobe PDF(2538Kb)  |  收藏  |  浏览/下载：176/44  |  提交时间：2019/10/28
Total synthesis of dryocrassin ABBA and its analogues with potential inhibitory activity against drug-resistant neuraminidases 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 17, 页码: 3846-3852
作者:  Hou, Bo;  Liu, Ze;  Yang, Xiao-Bei;  Zhu, Wen-Fei;  Li, Jin-Yu;  Yang, Liu;  Reng, Fu-Cai;  Lv, Yong-Feng;  Hu, Jiang-Miao;  Liao, Guo-Yang;  Zhou, Jun
浏览  |  Adobe PDF(1817Kb)  |  收藏  |  浏览/下载：137/30  |  提交时间：2019/09/10
Dryocrassin ABBA  Neuraminidase  Total synthesis  Shanghai H7N9  Anhui H7N9  
Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin 期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 8, 页码: 1122-+
作者:  Zhu, Huifang;  Wang, Bin;  Kong, Lingmei;  An, Tao;  Li, Gentao;  Zhou, Hongyu;  Gong, Liang;  Zhao, Zhangxun;  Gong, Yaxiao;  Sun, Handong;  Puno, Pematenzin;  Li, Yan
浏览  |  Adobe PDF(4600Kb)  |  收藏  |  浏览/下载：169/31  |  提交时间：2019/10/14