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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
Authors:
Wang,Yi-Ting
;
Long,Xin-Yan
;
Ding,Xiao
;
Fan,Shi-Rui
;
Cai,Jie-Yun
;
Yang,Bi-Juan
;
Zhang,Xin-Fang
;
Luo,Rong-hua
;
Yang,Lian
;
Ruan,Ting
;
Ren,Juan
;
Jing,Chen-Xu
;
Zheng,Yong-Tang
;
Hao,Xiao-Jiang
;
Chen,Duo-Zhi
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View/Download:63/0
  |  
Submit date:2022/04/02
Phenanthridine
Nucleocapsid protein
SARS-CoV-2
N-terminal domain
N-TERMINAL DOMAIN
CORONAVIRUS
Arabidopsis SIGMA FACTOR BINDING PROTEIN1 (SIB1) and SIB2 inhibit WRKY75 function in abscisic acid-mediated leaf senescence and seed germination
期刊论文
JOURNAL OF EXPERIMENTAL BOTANY, 2022, 卷号: 73, 期号: 1, 页码: 182-196
Authors:
Zhang,Haiyan
;
Zhang,Liping
;
Ji,Yunrui
;
Jing,Yifen
;
Li,Lanxin
;
Chen,Yanli
;
Wang,Ruling
;
Zhang,Huimin
;
Yu,Diqiu
;
Chen,Ligang
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  |  
Submit date:2022/04/02
Abscisic acid
GOLDEN 2-LIKE1/2
leaf senescence
seed germination
SIGMA FACTOR BINDING PROTEIN
WRKY75
TRANSCRIPTION FACTOR WRKY75
MOTIF-CONTAINING PROTEINS
SALICYLIC-ACID
PLANT SENESCENCE
KINASES
GENES
GROWTH
A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids
期刊论文
PLANT PHYSIOLOGY, 2022, 卷号: 188, 期号: 3, 页码: 1496-1506
Authors:
Song,Jiao-Jiao
;
Fang,Xin
;
Li,Chen-Yi
;
Jiang,Yan
;
Li,Jian-Xu
;
Wu,Sheng
;
Guo,Juan
;
Liu,Yan
;
Fan,Hang
;
Huang,Yan-Bo
;
Wei,Yu-Kun
;
Kong,Yu
;
Zhao,Qing
;
Xu,Jing-Jing
;
Hu,Yong-Hong
;
Chen,Xiao-Ya
;
Yang,Lei
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  |  
Submit date:2022/04/02
MOLECULAR-CLONING
BIOSYNTHESIS
TANSHINONES
EVOLUTION
CYTOTOXICITY
SUPERFAMILY
OXYGENASES
APOPTOSIS
SYNTHASE
Polycyclic polyprenylated acylphloroglucinols with immunosuppressive activity from Hypericum perforatum and absolute configurations assignment of previously reported analogues
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105144
Authors:
Guo,Yi
;
Cao,Yunfang
;
Qi,Changxing
;
Tong,Qingyi
;
Chen,Chunmei
;
Yang,Jing
;
Zhu,Hucheng
;
Zhang,Yonghui
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View/Download:28/0
  |  
Submit date:2022/04/02
Hypericum perforatum
Polycyclic polyprenylated acylphloroglucinols
Configuration assignment
Immunosuppressive activity
Neuroprotective activity
ST-JOHNS-WORT
PHLOROGLUCINOL DERIVATIVES
HYPERFORIN
INHIBITION
DEPRESSION
SKELETON
L.
Unprecedented polycyclic polyprenylated acylphloroglucinols with anti-Alzheimer's activity from St. John's wort
期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 12, 期号: 34, 页码: 11438-11446
Authors:
Guo,Yi
;
Huang,Fang
;
Sun,Weiguang
;
Zhou,Yuan
;
Chen,Chunmei
;
Qi,Changxing
;
Yang,Jing
;
Li,Xiao-Nian
;
Luo,Zengwei
;
Zhu,Hucheng
;
Wang,Xiaochuan
;
Zhang,Yonghui
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  |  
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  |  
Submit date:2022/04/02
AMYLOID-BETA
NEUROFIBRILLARY DEGENERATION
HYPERFORIN
NEUROTOXICITY
PATHOGENESIS
INHIBITION
BACE1
DRUG
TAU
New limonoids and quinolone alkaloids with cytotoxic and anti-platelet aggregation activities from Evodia rutaecarpa (Juss.) Benth
期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 104875
Authors:
Qin,Jing
;
Liao,Chao-Nan
;
Chen,Wei-wei
;
Li,Hong-you
;
Su,Jia
;
Wu,Xing-De
;
He,Jiang-bo
;
Zhang,Gao-hong
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View/Download:19/0
  |  
Submit date:2022/04/02
Limonoid
Quinolone alkaloid
Cytotoxic activity
Anti-platelet aggregation
Evodia rutaecarpa (Juss
) Benth
FRUITS
Trimeric and dimeric Aspidosperma-type alkaloids from leaves of Tabernaemontana divaricata 'Dwaft'
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105314
Authors:
Chen,Jing
;
Yu,Yang
;
Wu,Jing
;
Bao,Mei-Fen
;
Kongkiatpaiboon,Sumet
;
Schinnerl,Johann
;
Cai,Xiang-Hai
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  |  
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  |  
Submit date:2022/04/02
Tabernaemontana divaricata 'Dwaft'
Monoterpenoid indole alkaloid
Aspidosperma-type trimmers
Aspidosperma-type dimers
Cytotoxicity
MONOTERPENOID INDOLE ALKALOIDS
BISINDOLE ALKALOIDS
DIVERSE SKELETONS
A-I
CONOPHYLLINE
New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1648-1666
Authors:
Su,Lihua
;
Zhang,Xintian
;
Ma,Yunbao
;
Geng,Changan
;
Huang,Xiaoyan
;
Hu,Jing
;
Li,Tianze
;
Tang,Shuang
;
Shen,Cheng
;
Gao,Zhen
;
Zhang,Xuemei
;
Chen,Ji-Jun
View
  |  
Adobe PDF(4074Kb)
  |  
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View/Download:17/0
  |  
Submit date:2022/04/02
Guaianolide dimers
Artematrolides AeR
Artemisia atrovirens
Cytotoxicity
Cell cycle
Apoptosis
FARNESYL-PROTEIN TRANSFERASE
CELL-CYCLE ARREST
HEPATOCELLULAR-CARCINOMA
GUAIANOLIDES
LACTONES
INHIBITORS
ARTEMINOLIDE
APOPTOSIS
ARGYI
HELA
Artematrovirenins A-P, guaiane-type sesquiterpenoids with cytotoxicities against two hepatoma cell lines from Artemisia atrovirens
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105072
Authors:
Su,Li-Hua
;
Ma,Yun-Bao
;
Geng,Chang-An
;
Li,Tian-Ze
;
Huang,Xiao-Yan
;
Hu,Jing
;
Zhang,Xin
;
Tang,Shuang
;
Shen,Cheng
;
Gao,Zhen
;
Zhang,Xue-Mei
;
Chen,Ji-Jun
View
  |  
Adobe PDF(2611Kb)
  |  
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  |  
View/Download:21/4
  |  
Submit date:2022/04/02
Artemisia atrovirens
guaiane-type sesquiterpenoids
artematrovirenins A-P
HepG2 and Huh7 cell lines
antihepatic cytotoxicity
LACTONES
CONSTITUENTS
GUAIANOLIDES
Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift
期刊论文
PHYTOMEDICINE, 2021, 卷号: 91, 页码: 153707
Authors:
Zhang,Xin-Tian
;
Hu,Jing
;
Su,Li-Hua
;
Geng,Chang-An
;
Chen,Ji-Jun
View
  |  
Adobe PDF(6313Kb)
  |  
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  |  
View/Download:11/2
  |  
Submit date:2022/04/02
Artemisia atrovirens
Cervical cancer
ERK pathway
Cell metabolism
ALKALINE-PHOSPHATASE
SIGNALING PATHWAY
DIFFERENTIATION
APOPTOSIS
ERK
MECHANISMS