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Discovery of isopenicin A, a meroterpenoid as a novel inhibitor of tubulin polymerization 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020
作者:  Chen, Lin;  Fan, Dong-Mei;  Tang, Jian-Wei;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Puno, Pema-Tenzin;  Li, Yan
Adobe PDF(1132Kb)  |  收藏  |  浏览/下载：133/43  |  提交时间：2021/01/05
Design, Synthesis, and Anticancer Activity of Novel Trimethoxyphenyl-Derived Chalcone-Benzimidazolium Salts 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 23, 页码: 20381-20393
作者:  Yang, Jun-Li;  Ma, Yong-Hui;  Li, Yan-Hua;  Zhang, Yi-Peng;  Tian, Hong-Chang;  Huang, Yuan-Cheng;  Li, Yan;  Chen, Wen;  Yang, Li-Juan
Adobe PDF(2215Kb)  |  收藏  |  浏览/下载：175/50  |  提交时间：2020/03/18
Synthesis and Cytotoxicities of Novel Podophyllotoxin Xyloside Derivatives 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2019, 卷号: 14, 期号: 7, 页码: 6
作者:  Zi, Cheng-Ting;  Yang, Liu;  Zhang, Bang-Lei;  Li, Yan;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao;  Zhou, Jun
Adobe PDF(352Kb)  |  收藏  |  浏览/下载：150/34  |  提交时间：2019/09/10
podophyllotoxin  butyrylated xyloside  cytotoxicity  synthesis  
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：146/34  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Design, Synthesis, and Biological Activities of Vibsanin B Derivatives: A New Class of HSP90 C-Terminal Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 9053-9066
作者:  Shao, Li-Dong;  Su, Jia;  Ye, Baixin;  Liu, Jiang-Xin;  Zuo, Zhi-Li;  Li, Yan;  Wang, Yue-Ying;  Xia, Chengfeng;  Zhao, Qin-Shi
Adobe PDF(5724Kb)  |  收藏  |  浏览/下载：365/41  |  提交时间：2017/12/18
Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 14, 页码: 3911-3914
作者:  Wang, Li;  Yang, Jing;  Kong, Ling-Mei;  Deng, Jun;  Xiong, Zijun;  Huang, Jianping;  Luo, Jianping;  Yan, Yijun;  Hu, Yikao;  Li, Xiao-Nian;  Li, Yan;  Zhao, Yong;  Huang, Sheng-Xiong
Adobe PDF(1338Kb)  |  收藏  |  浏览/下载：256/73  |  提交时间：2017/10/23
Protein-kinase-c  Phorbol Esters  Biological Evaluation  Biosynthesis  (+)-phorbol  Analogs  Cancer  Seeds  
Synthesis and cytotoxic activity of novel tetrahydrobenzodifuran-imidazolium salt derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 8, 页码: 1808-1814
作者:  Zhang, Chao-Bo;  Liu, Yang;  Liu, Zheng-Fen;  Duan, Sheng-Zu;  Li, Min-Yan;  Chen, Wen;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong
Adobe PDF(1192Kb)  |  收藏  |  浏览/下载：614/103  |  提交时间：2017/06/30
Tetrahydrobenzodifurans  Imidazolium Salts  Cytotoxic Activity  Cell Cycle  Apoptosis  
microRNA-375 inhibits colorectal cancer cells proliferation by downregulating JAK2/STAT3 and MAP3K8/ERK signaling pathways 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 10, 页码: 16633-16641
作者:  Wei, Ran;  Yang, Qin;  Han, Bing;  Li, Yan;  Yao, Kun;  Yang, Xiuyu;  Chen, Zexi;  Yang, Shanshan;  Zhou, Jiaqi;  Li, Meizhang;  Yu, Haijing;  Yu, Min;  Cui, Qinghua
Adobe PDF(12068Kb)  |  收藏  |  浏览/下载：409/35  |  提交时间：2017/04/19
Microrna-375  Colorectal Cancer  Jak2/stat3 Pathway  Map3k8/erk Pathway  Atg7  
Ciclopirox olamine inhibits mTORC1 signaling by activation of AMPK 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2016, 卷号: 116, 页码: 39-50
作者:  Zhou, Hongyu;  Shang, Chaowei;  Wang, Min;  Shen, Tao;  Kong, Lingmei;  Yu, Chunlei;  Ye, Zhennan;  Luo, Yan;  Liu, Lei;  Li, Yan;  Huang, Shile
Adobe PDF(3794Kb)  |  收藏  |  浏览/下载：168/36  |  提交时间：2017/01/05
Ciclopirox  Mtor  Ampk  Tsc2  Raptor  
N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells 期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2016, 卷号: 35
作者:  Wang, Min;  Zhou, Ankun;  An, Tao;  Kong, Lingmei;  Yu, Chunlei;  Liu, Jianmei;  Xia, Chengfeng;  Zhou, Hongyu;  Li, Yan
Adobe PDF(1734Kb)  |  收藏  |  浏览/下载：178/30  |  提交时间：2016/06/27
N-hydroxyphthalimide  Mtor  Inhibitor  Cancer  Mitochondrial Apoptosis