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Oligosaccharides from fucosylated glycosaminoglycan prevent breast cancer metastasis in mice by inhibiting heparanase activity and angiogenesis 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 166, 页码: 105527
作者:  Zhou,Lutan;  Yin,Ronghua;  Gao,Na;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Ren,Lin;  Yang,Lian;  Zuo,Zhili;  Zhang,Hongbin;  Zhao,Jinhua
浏览  |  Adobe PDF(8336Kb)  |  收藏  |  浏览/下载：188/20  |  提交时间：2022/04/02
Oligosaccharides  Heparanase  Angiogenesis  Metastasis  FIBROBLAST-GROWTH-FACTOR  TUMOR-GROWTH  SULFATE PROTEOGLYCANS  MAMMALIAN HEPARANASE  COMBINATION  MECHANISMS  DISCOVERY  BINDING  TARGET  PI-88  
Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives 期刊论文
BIOMACROMOLECULES, 2021, 卷号: 22, 期号: 3, 页码: 1244-1255
作者:  Yin,Ronghua;  Zhou,Lutan;  Gao,Na;  Lin,Lisha;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Zuo,Zhili;  Hu,Kaifeng;  Huang,Shengxiong;  Liu,Jikai;  Zhao,Jinhua
浏览  |  Adobe PDF(4401Kb)  |  收藏  |  浏览/下载：137/30  |  提交时间：2022/04/02
FUCOSYLATED CHONDROITIN SULFATE  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  SEA-CUCUMBER  FUCOSE BRANCHES  BODY-WALL  INDEPENDENT INHIBITION  POLYSACCHARIDE ACCOUNT  FACTOR XASE  HEPARIN  
A regular fucan sulfate from Stichopus herrmanni and its peroxide depolymerization: Structure and anticoagulant activity 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 256, 页码: 117513
作者:  Li,Xiaomei;  Li,Shanni;  Liu,Jie;  Lin,Lisha;  Sun,Huifang;  Yang,Wenjiao;  Cai,Ying;  Gao,Na;  Zhou,Lutan;  Qin,Hongbo;  Yin,Ronghua;  Zhao,Jinhua
浏览  |  Adobe PDF(3183Kb)  |  收藏  |  浏览/下载：126/23  |  提交时间：2022/04/02
fucan sulfate  peroxide depolymerization  oligosaccharides  anti-thrombin activity  FUCOSYLATED CHONDROITIN SULFATE  FREE-RADICAL DEPOLYMERIZATION  PHYSICOCHEMICAL CHARACTERISTICS  REPEATING UNIT  BODY-WALL  SEA  FUCOIDAN  GLYCOSAMINOGLYCAN  POLYSACCHARIDES  HEPARIN  
Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 423-435
作者:  Shang, Feineng;  Gao, Na;  Yin, Ronghua;  Lin, Lisha;  Xiao, Chuang;  Zhou, Lutan;  Li, Zi;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(3117Kb)  |  收藏  |  浏览/下载：302/89  |  提交时间：2018/05/08
Glycosaminoglycan  Oligosaccharide  Anticoagulant  Intrinsic Factor Xase  
Enzyme-Assisted Extraction Optimization, Characterization and Antioxidant Activity of Polysaccharides from Sea Cucumber Phyllophorus proteus 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 3, 页码: 590
作者:  Qin, Yujing;  Yuan, Qingxia;  Zhang, Yuexing;  Li, Jialu;  Zhu, Xinjiao;  Zhao, Lingling;  Wen, Jing;  Liu, Jikai;  Zhao, Longyan;  Zhao, Jinhua
浏览  |  Adobe PDF(5270Kb)  |  收藏  |  浏览/下载：302/77  |  提交时间：2018/07/02
Sea Cucumber  Polysaccharide  Enzyme-assisted Extraction  Characterization  Antioxidant Activity  
Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycan 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 卷号: 112, 期号: 27, 页码: 8284-8289
作者:  Zhao, Longyan;  Wu, Mingyi;  Xiao, Chuang;  Yang, Lian;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Chen, Jun;  Chen, Jianchao;  Liu, Jikai;  Qin, Hongbo;  Zhao, Jinhua
浏览  |  Adobe PDF(1067Kb)  |  收藏  |  浏览/下载：348/46  |  提交时间：2015/12/17
Anticoagulant  Inhibitors  Oligosaccharides  Carbohydrates  Drug Discovery  
Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor Xase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 92, 页码: 257-269
作者:  Wu, Mingyi;  Wen, Dandan;  Gao, Na;  Xiao, Chuang;  Yang, Lian;  Xu, Li;  Lian, Wu;  Peng, Wenlie;  Jiang, Jianmin;  Zhao, Jinhua;  Jiang,JM (reprint author),Sun Yat Sen Univ,Sch Pharmaceut Sci,Guangzhou 510006,Guangdong,Peoples R China.;  lssjjm@mail.sysu.edu.cn;  zhao.jinhua@yahoo.com
浏览  |  Adobe PDF(1936Kb)  |  收藏  |  浏览/下载：362/115  |  提交时间：2015/06/29
Fucosylated Chondroitin Sulfate  Factor Xase Inhibitor  Anticoagulant  Antithrombotic  Structure-activity Relationship  
Structural Analysis and Anticoagulant Activities of the Novel Sulfated Fucan Possessing a Regular Well-Defined Repeating Unit from Sea Cucumber 期刊论文
MARINE DRUGS, 2015, 卷号: 13, 期号: 4, 页码: 2063-2084
作者:  Wu, Mingyi;  Xu, Li;  Zhao, Longyan;  Xiao, Chuang;  Gao, Na;  Luo, Lan;  Yang, Lian;  Li, Zi;  Chen, Lingyun;  Zhao, Jinhua
浏览  |  Adobe PDF(2239Kb)  |  收藏  |  浏览/下载：326/65  |  提交时间：2015/06/29
The depolymerized fucosylated chondroitin sulfate from sea cucumber potently inhibits HIV replication via interfering with virus entry 期刊论文
CARBOHYDRATE RESEARCH, 2013, 卷号: 380, 页码: 64-69
作者:  Huang, Ning;  Wu, Ming-Yi;  Zheng, Chang-Bo;  Zhu, Lin;  Zhao, Jin-Hua;  Zheng, Yong-Tang
浏览  |  Adobe PDF(1128Kb)  |  收藏  |  浏览/下载：640/98  |  提交时间：2013/11/12
Fucosylated Chondroitin Sulfate  Hiv-1  Anti-hiv Agent  Hiv Entry  
Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitope 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2013, 卷号: 1830, 期号: 10, 页码: 4681-4691
作者:  Lian, Wu;  Wu, Mingyi;  Huang, Ning;  Gao, Na;  Xiao, Chuang;  Li, Zi;  Zhang, Zhigang;  Zheng, Yongtang;  Peng, Wenlie;  Zhao, Jinhua
浏览  |  Adobe PDF(2650Kb)  |  收藏  |  浏览/下载：503/100  |  提交时间：2013/11/12
Glycosaminoglycan  Anti-human Immunodeficiency Virus Activity  Envelope Glycoprotein 120  Cluster Of Differentiation 4 Induced Epitope  Biolayer Interferometry  Structure-activity Relationship