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Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
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Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Structural basis of the mechanism of beta-methyl epimerization by enzyme MarH 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 卷号: 17, 期号: 44, 页码: 9605-9614
作者:  Liu, Bin;  Hou, Yan;  Wang, Xiaozheng;  Ma, Xiaofang;  Fang, Shiqi;  Huang, Tao;  Chen, Yanli;  Bai, Zhiqiang;  Lin, Shuangjun;  Zhang, Rundong;  Hu, Kaifeng
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A New Heliquinomycin Analogue with Immunosuppressive Activity from Streptomyces sp. jys28 期刊论文
RECORDS OF NATURAL PRODUCTS, 2019, 卷号: 13, 期号: 6, 页码: 456-461
作者:  Su, Can;  Liu, Chongxi;  Wang, Yongjiang;  Xiang, Wen-Sheng;  Zou, Chenggang;  Huang, Sheng-Xiong
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Heliquinomycin  immunosuppressive activity  antibacterial activity  
Alkaloids isolated from Tabemaemontana bufalina display xanthine oxidase inhibitory activity 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 166, 页码: 8
作者:  Shi, Bao-Bao;  Chen, Jing;  Bao, Mei-Fen;  Zeng, Ying;  Cai, Xiang-Hai
浏览  |  Adobe PDF(956Kb)  |  收藏  |  浏览/下载：231/74  |  提交时间：2019/10/28
Tabernaemontana bufalina apocynaceae  Alkaloid  Taberhaines A-D  Apparicine  Xanthine oxidase inhibitor  
Structure and heparanase inhibitory activity of a new glycosaminoglycan from the slug Limacus flavus 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 220, 页码: 176-184
作者:  He, Zhicheng;  Zhou, Lutan;  Lin, Lisha;  Yin, Ronghua;  Zhao, Jinhua
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Slug  Glycosaminoglycan  Chemical structure  Depolymerization  Heparanase inhibition  
Anti-BACE1 and anti-AchE activities of undescribed spiro-dioxolane-containing meroterpenoids from the endophytic fungus Aspergillus terreus Thom 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 165, 页码: 8
作者:  Qi, Changxing;  Zhou, Qun;  Gao, Weixi;  Liu, Mengting;  Chen, Chunmei;  Li, Xiao-Nian;  Lai, Yongji;  Zhou, Yuan;  Li, Dongyan;  Hu, Zhengxi;  Zhu, Hucheng;  Zhang, Yonghui
浏览  |  Adobe PDF(1128Kb)  |  收藏  |  浏览/下载：283/151  |  提交时间：2019/10/14
Aspergillus terreus Thom  endophytic fungus  3,5-Dimethylorsellinic acid-based meroterpenoid  Adducts  Alzheimer's disease  
Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors 期刊论文
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
作者:  Sajesh, Babu, V;  On, Ngoc H.;  Omar, Refaat;  Alrushaid, Samaa;  Kopec, Brian M.;  Wang, Wei-Guang;  Sun, Han-Dong;  Lillico, Ryan;  Lakowski, Ted M.;  Siahaan, Teruna J.;  Davies, Neal M.;  Puno, Pema-Tenzin;  Vanan, Magimairajan Issai;  Miller, Donald W.
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blood-brain barrier (BBB)  drug delivery  transient modulation  HAV6 cadherin peptide  adenanthin  magnetic resonance imaging (MRI)  medulloblastoma  
Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin 期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 8, 页码: 1122-+
作者:  Zhu, Huifang;  Wang, Bin;  Kong, Lingmei;  An, Tao;  Li, Gentao;  Zhou, Hongyu;  Gong, Liang;  Zhao, Zhangxun;  Gong, Yaxiao;  Sun, Handong;  Puno, Pematenzin;  Li, Yan
浏览  |  Adobe PDF(4600Kb)  |  收藏  |  浏览/下载：187/33  |  提交时间：2019/10/14
Community Structures and Antifungal Activity of Root-Associated Endophytic Actinobacteria of Healthy and Diseased Soybean 期刊论文
MICROORGANISMS, 2019, 卷号: 7, 期号: 8, 页码: 15
作者:  Liu, Chongxi;  Zhuang, Xiaoxin;  Yu, Zhiyin;  Wang, Zhiyan;  Wang, Yongjiang;  Guo, Xiaowei;  Xiang, Wensheng;  Huang, Shengxiong
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Sclerotinia sclerotiorum (Lib  ) de Bary  diseased soybean root  antifungal activity  actinobacterial community  new agroactive compounds  
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
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Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research