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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao;  Shen, Wen;  Zhang, Shuqun;  Wang, LiangLiang;  Yang, Weimin;  Zuo, Zhili
收藏  |  浏览/下载：186/0  |  提交时间：2020/03/18
Adenylyl cyclases  Homology modeling  Consensus scoring  Molecular dynamics simulation  Virtual screening  Biological evaluation  
Aromatization of natural products by a specialized detoxification enzyme 期刊论文
NATURE CHEMICAL BIOLOGY, 2020, 卷号: 16, 期号: 3, 页码: 11
作者:  Huang, Jin-Quan;  Fang, Xin;  Tian, Xiu;  Chen, Ping;  Lin, Jia-Ling;  Guo, Xiao-Xiang;  Li, Jian-Xu;  Fan, Zhen;  Song, Wei-Meng;  Chen, Fang-Yan;  Ahati, Ruzha;  Wang, Ling-Jian;  Zhao, Qing;  Martin, Cathie;  Chen, Xiao-Ya
收藏  |  浏览/下载：152/0  |  提交时间：2020/03/18
Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity 期刊论文
BMC Cancer, 2019, 卷号: 19, 期号: 1
作者:  Wang,Ning;  Fan,Yanhua;  Yuan,Chun-Mao;  Song,Jialei;  Yao,Yao;  Liu,Wuling;  Gajendran,Babu;  Zacksenhaus,Eldad;  Li,Yanmei;  Liu,Jielin;  Hao,Xiao Jiang;  Ben-David,Yaacov
收藏  |  浏览/下载：146/0  |  提交时间：2019/08/13
Cancer  Leukemia  Chinese medicinal plant  Melia azedarach  Drug screen  ERK1/2 agonists  Differentiation  Apoptosis  
Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning 期刊论文
CELL REPORTS, 2019, 卷号: 28, 期号: 2, 页码: 541-+
作者:  Ma, Pengcheng;  Song, Ning-Ning;  Li, Yongxin;  Zhang, Qiong;  Zhang, Lei;  Zhang, Longlong;  Kong, Qinghua;  Ma, Li;  Yang, Xiangcai;  Ren, Biyu;  Li, Chaocui;  Zhao, Xudong;  Li, Yan;  Xu, Ying;  Gao, Xiang;  Ding, Yu-Qiang;  Mao, Bingyu
浏览  |  Adobe PDF(5547Kb)  |  收藏  |  浏览/下载：252/45  |  提交时间：2019/08/19
Allelochemicals from the rhizosphere of Lanzhou lily: Discovery of the autotoxic compounds of a bulb crop 期刊论文
SCIENTIA HORTICULTURAE, 2019, 卷号: 250, 页码: 121-126
作者:  Yan, Zhiqiang;  He, Xiaofeng;  Guo, Kai;  Li, Xiuzhuang;  Yang, Xiaoyan;  Jin, Hui;  Su, Anxiang;  Zheng, Weili;  Xu, Lihong;  Song, Xiaoxia;  Qin, Bo
浏览  |  Adobe PDF(1919Kb)  |  收藏  |  浏览/下载：152/27  |  提交时间：2019/07/29
Lanzhou lily  Rhizosphere soil  Allelochemicals  Phytotoxicity  Autotoxicity  
Diterpenoids and sesquiterpenoids from the stem bark of Metasequoia glyptostroboides 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 161, 页码: 86-96
作者:  Tu, Wen-Chao;  Qi, Yan-Yan;  Ding, Lin-Fen;  Yang, Hui;  Liu, Jiang-Xin;  Peng, Li-Yan;  Song, Liu-Dong;  Gong, Xun;  Wu, Xing-De;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1045Kb)  |  收藏  |  浏览/下载：234/73  |  提交时间：2019/07/29
Metasequoia glyptostroboides Hu & WC Cheng  Cupressaceae  Sesquiterpenoids  Diterpenoids  Cytotoxicity  
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
浏览  |  Adobe PDF(2607Kb)  |  收藏  |  浏览/下载：295/50  |  提交时间：2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Enantioselective N-Heterocyclic Carbene-Catalyzed Synthesis of Spirocyclic Oxindole-benzofuroazepinones 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 24, 页码: 15225-15235
作者:  Gao, Zhong-Hua;  Chen, Kun-Quan;  Zhang, Yan;  Kong, Ling-Mei;  Li, Yan;  Ye, Song
收藏  |  浏览/下载：246/0  |  提交时间：2019/03/18
Cytotoxic sesquiterpenoids from the leaves of Magnolia grandiflora 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 155, 页码: 182-190
作者:  Ding, Lin-Fen;  Su, Jia;  Pan, Zheng-Hong;  Zhang, Zhi-Jun;  Li, Xiao-Nian;  Song, Liu-Dong;  Wu, Xing-De;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1049Kb)  |  收藏  |  浏览/下载：589/149  |  提交时间：2018/11/12
Magnolia Grandiflora (Magnoliaceae)  Sesquiterpenoids  Cytotoxic Activity  Nf-kappa b Transcriptional Activity  
LC-MS guided isolation of gracilistones A and B, a pair of diastereomeric sesquiterpenoids with an unusual tetrahydrofuran-fused tricyclic skeleton from Acanthopanax gracilistylus and their potential anti-inflammatory activities 期刊论文
FITOTERAPIA, 2018, 卷号: 130, 页码: 265-271
作者:  Xu, Hong-Bo;  Yang, Tong-Hua;  Xie, Pei;  Tang, Zhi-Shu;  Song, Xiao;  Xu, Huai-Li;  Li, Yan-Hong;  Zhang, Dong-Bo;  Liu, Yan-Ru;  Liang, Yan-Ni;  Zhang, Yu;  Liu, Shi-Jun;  Wei, Si-Min;  Sun, Chen;  Liu, Hong-Bo;  Deng, Chong;  Wang, Wei
收藏  |  浏览/下载：233/0  |  提交时间：2018/12/03
Acanthopanax gracilistylus  Eudesmane-type sesquiterpenoid  LC-MS  Anti-inflammation  Anti-oxidant  Xanthine oxidase