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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:  Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting;  Zhao,Qi;  Cheng,Yan;  Lin,Qiuxia;  Zhang,Binbin;  Liu,Aiming;  Rao,Qianru;  Huang,Jianfeng;  Zhao,Jinhua;  Gonzalez,Frank J.;  Li,Fei
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Intestinal bleeding  Triptolide  Celastrol  Intestinal FXR  Tripterygium wilfordii  FARNESOID-X-RECEPTOR  BACTERIAL TRANSLOCATION  ACTIVATION  INFLAMMATION  DYSFUNCTION  TRIPTOLIDE  MICROBIOTA  PREVENTS  OBESITY  MICE  
Metabolomics Reveals Gut Microbiota Contribute to PPARα Deficiency-Induced Alcoholic Liver Injury 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023, 卷号: 22, 期号: 7, 页码: 2327-2338
作者:  Zhang,Ting;  Bao,Lijuan;  Zhao,Qi;  Wu,Zhanxuan E. E.;  Dai,Manyun;  Rao,Qianru;  Li,Fei
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metabolomics  alcohol-induced liver injury  gut microbiota  PPAR & alpha  AROMATIC-AMINO-ACIDS  LIPID-METABOLISM  FED MICE  MODULATION  DISEASE  AXIS  OLEOYLETHANOLAMIDE  AGONIST  OBESITY  DEATH  
Metabolomics Reveals Gut Microbiota Contribute to PPAR & alpha; Deficiency-Induced Alcoholic Liver Injury 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023
作者:  Zhang,Ting;  Bao,Lijuan;  Zhao,Qi;  Wu,Zhanxuan E. E.;  Dai,Manyun;  Rao,Qianru;  Li,Fei
浏览  |  Adobe PDF(9616Kb)  |  收藏  |  浏览/下载：2/0  |  提交时间：2024/07/10
metabolomics  alcohol-induced liver injury  gut microbiota  PPAR & alpha  AROMATIC-AMINO-ACIDS  LIPID-METABOLISM  FED MICE  MODULATION  DISEASE  AXIS  OLEOYLETHANOLAMIDE  AGONIST  OBESITY  DEATH  
Leucosceptrane Sesterterpenoids as a New Type of Natural Immunosuppressive Agents in Treating Sepsis 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 67, 期号: 1, 页码: 513-528
作者:  Guo,Kai;  Zhou,Ting-Ting;  Luo,Shi-Hong;  Liu,Yan-Chun;  Liu,Yan;  Li,Sheng-Hong
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GLANDULAR TRICHOMES  PRODUCTS  HARBOR  CANUM  
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction 期刊论文
NATURE CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 4, 页码: 468-+
作者:  Guo,Yingjie;  Zhang,Huan;  Yan,Chen;  Shen,Birong;  Zhang,Yue;  Guo,Xiangyang;  Sun,Sha;  Yu,Fan;  Yan,Jiayun;  Liu,Ronghe;  Zhang,Qianping;  Zhang,Di;  Liu,Haiyang;  Liu,Yang;  Zhang,Yaoyao;  Li,Wenlei;  Qin,Jiangyu;  Lv,He;  Wang,Zhaoxia;  Yuan,Yun;  Yang,Jie-Feng;  Zhong,Ya-Ting;  Gao,Song;  Zhou,Bing;  Liu,Lei;  Kong,Deling;  Hao,Xiaojiang;  Hu,Junjie;  Chen,Quan
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ENDOPLASMIC-RETICULUM  PROVIDE INSIGHT  MITOFUSIN 2  MFN1  DYNAMICS  REQUIRES  DEFECTS  FISSION  CELLS  
Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum 期刊论文
FITOTERAPIA, 2023, 卷号: 165, 页码: 105402
作者:  Guo,Kai;  Ren,Xue;  Zhou,Ting-Ting;  Li,Tao;  Liu,Yan-Chun;  Tao,Yang;  Hu,Hong;  Li,Dan;  Liu,Yan;  Li,Sheng-Hong
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Lomatogonium carinthiacum  Gentianaceae  Monoterpenoids  Monoterpenoid alkaloids  Sesquiterpenoids  Immunosuppressive activity  STRUCTURAL ELUCIDATION  GLYCOSIDES  SECOIRIDOIDS  GLUCOSIDE  PART  
The extracts of Lobaria pindarensis, an edible lichen from Himalayas, suppress inflammatory response and fibrillation of amyloid β-protein in cultured microglial cells: Active depsidones, norstictic acid and stictic acid, are responsible for the functions 期刊论文
JOURNAL OF FUNCTIONAL FOODS, 2023, 卷号: 107, 页码: 105607
作者:  Yang,Mei-Xia;  Cheng,Edwin Hok-Chi;  Ospondpant,Dusadee;  Tung,Ka-Ki;  Wang,Li-Song;  Lin,Sheng-Ying;  Lai,Queenie Wing-Sze;  Wu,Qi-Yun;  Xia,Ying-Jie;  Leung,Ka-Wing;  Duan,Ran;  Dong,Tina Ting-Xia;  Tsim,Karl Wah-Keung
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Alzheimer's disease  Inflammation  Fibrillar A beta  Lichen  Lobaria pindarensis  Depsidone  IN-SILICO  IDENTIFICATION  INHIBITORS  
Tripterygium wilfordii protects against an animal model of autoimmune hepatitis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 309, 页码: 116365
作者:  Zhang,Ting;  Rao,Qianru;  Dai,Manyun;  Zhao,Qi;  Li,Fei
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Tripterygium wilfordii tablets  Celastrol  Concanavalin A  Autophagy  TFEB  PXR  PREGNANE-X-RECEPTOR  CHOLESTATIC LIVER-INJURY  CELASTROL PROTECTS  AUTOPHAGY  OBESITY  DYSFUNCTION  DOMAIN  
Defensive Specialized Metabolites from the Latex of Euphorbia jolkinii 期刊论文
JOURNAL OF CHEMICAL ECOLOGY, 2023
作者:  Luo,Shihong;  Huang,Chunshuai;  Hua,Juan;  Jing,Shuxi;  Teng,Linlin;  Tang,Ting;  Liu,Yan;  Li,Shenghong
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Plant latex  Euphorbia jolkinii  meta-Tyrosine  Phytotoxic activity  Specialized metabolites  PLANT LATEX  META-TYROSINE  DITERPENOIDS  ROOTS  ACID  DERIVATIVES  COMPONENTS  GLYCOSIDE  FRUIT  
Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 9, 页码: 8113
作者:  Xu,Xinglian;  Deng,Lulu;  Tang,Yaling;  Li,Jiang;  Zhong,Ting;  Hao,Xiaojiang;  Fan,Yanhua;  Mu,Shuzhen
浏览  |  Adobe PDF(5829Kb)  |  收藏  |  浏览/下载：32/9  |  提交时间：2024/05/09
leukemia  sanguinarine  c-MET  MAPK  PI3K/mTOR  STAT3  MET