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Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum
Guo,Kai; Ren,Xue; Zhou,Ting-Ting; Li,Tao; Liu,Yan-Chun; Tao,Yang; Hu,Hong; Li,Dan; Liu,Yan; Li,Sheng-Hong
2023
Source PublicationFITOTERAPIA
ISSN1873-6971
Volume165Pages:105402
AbstractSystematic phytochemical investigation on the Mongolian medicinal herb Lomatogonium carinthiacum led to the isolation of 12 monoterpenoids including three new secoiridoids (1, 2 and 4) and one new iridoid glycoside (13), one new monoterpenoid alkaloid (3), and three new sesquiterpenoids (14-16). Comprehensive spectroscopic analysis (including 1D and 2D NMR, and HRESIMS) and quantum chemistry computations (including ECD and NMR calculations) were applied to elucidate their structures. Weak immunosuppressive activities were observed for the new isolates via inhibiting T cell proliferation and cytokine IFN-gamma secretion in vitro.
KeywordLomatogonium carinthiacum Gentianaceae Monoterpenoids Monoterpenoid alkaloids Sesquiterpenoids Immunosuppressive activity STRUCTURAL ELUCIDATION GLYCOSIDES SECOIRIDOIDS GLUCOSIDE PART
Subject AreaPharmacology & Pharmacy
DOI10.1016/j.fitote.2022.105402
Indexed BySCI
WOS IDWOS:000915853600001
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Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/75519
Collection中国科学院昆明植物研究所
Recommended Citation
GB/T 7714
Guo,Kai,Ren,Xue,Zhou,Ting-Ting,et al. Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum[J]. FITOTERAPIA,2023,165:105402.
APA Guo,Kai.,Ren,Xue.,Zhou,Ting-Ting.,Li,Tao.,Liu,Yan-Chun.,...&Li,Sheng-Hong.(2023).Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum.FITOTERAPIA,165,105402.
MLA Guo,Kai,et al."Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum".FITOTERAPIA 165(2023):105402.
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