Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum

doi:10.1016/j.fitote.2022.105402

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	Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum
	Guo,Kai; Ren,Xue; Zhou,Ting-Ting; Li,Tao; Liu,Yan-Chun; Tao,Yang; Hu,Hong; Li,Dan; Liu,Yan; Li,Sheng-Hong
	2023
发表期刊	FITOTERAPIA
ISSN	1873-6971
卷号	165 页码:105402
摘要	Systematic phytochemical investigation on the Mongolian medicinal herb Lomatogonium carinthiacum led to the isolation of 12 monoterpenoids including three new secoiridoids (1, 2 and 4) and one new iridoid glycoside (13), one new monoterpenoid alkaloid (3), and three new sesquiterpenoids (14-16). Comprehensive spectroscopic analysis (including 1D and 2D NMR, and HRESIMS) and quantum chemistry computations (including ECD and NMR calculations) were applied to elucidate their structures. Weak immunosuppressive activities were observed for the new isolates via inhibiting T cell proliferation and cytokine IFN-gamma secretion in vitro.
关键词	Lomatogonium carinthiacum Gentianaceae Monoterpenoids Monoterpenoid alkaloids Sesquiterpenoids Immunosuppressive activity STRUCTURAL ELUCIDATION GLYCOSIDES SECOIRIDOIDS GLUCOSIDE PART
学科领域	Pharmacology & Pharmacy
DOI	10.1016/j.fitote.2022.105402
收录类别	SCI
WOS记录号	WOS:000915853600001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75519
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Guo,Kai,Ren,Xue,Zhou,Ting-Ting,et al. Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum[J]. FITOTERAPIA,2023,165:105402.
APA	Guo,Kai.,Ren,Xue.,Zhou,Ting-Ting.,Li,Tao.,Liu,Yan-Chun.,...&Li,Sheng-Hong.(2023).Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum.FITOTERAPIA,165,105402.
MLA	Guo,Kai,et al."Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum".FITOTERAPIA 165(2023):105402.

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