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| Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum | |
Guo,Kai; Ren,Xue; Zhou,Ting-Ting; Li,Tao; Liu,Yan-Chun; Tao,Yang ; Hu,Hong; Li,Dan; Liu,Yan; Li,Sheng-Hong
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| 2023 | |
| Source Publication | FITOTERAPIA
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| ISSN | 1873-6971 |
| Volume | 165Pages:105402 |
| Abstract | Systematic phytochemical investigation on the Mongolian medicinal herb Lomatogonium carinthiacum led to the isolation of 12 monoterpenoids including three new secoiridoids (1, 2 and 4) and one new iridoid glycoside (13), one new monoterpenoid alkaloid (3), and three new sesquiterpenoids (14-16). Comprehensive spectroscopic analysis (including 1D and 2D NMR, and HRESIMS) and quantum chemistry computations (including ECD and NMR calculations) were applied to elucidate their structures. Weak immunosuppressive activities were observed for the new isolates via inhibiting T cell proliferation and cytokine IFN-gamma secretion in vitro. |
| Keyword | Lomatogonium carinthiacum Gentianaceae Monoterpenoids Monoterpenoid alkaloids Sesquiterpenoids Immunosuppressive activity STRUCTURAL ELUCIDATION GLYCOSIDES SECOIRIDOIDS GLUCOSIDE PART |
| Subject Area | Pharmacology & Pharmacy |
| DOI | 10.1016/j.fitote.2022.105402 |
| Indexed By | SCI |
| WOS ID | WOS:000915853600001 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/75519 |
| Collection | 中国科学院昆明植物研究所 |
| Recommended Citation GB/T 7714 | Guo,Kai,Ren,Xue,Zhou,Ting-Ting,et al. Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum[J]. FITOTERAPIA,2023,165:105402. |
| APA | Guo,Kai.,Ren,Xue.,Zhou,Ting-Ting.,Li,Tao.,Liu,Yan-Chun.,...&Li,Sheng-Hong.(2023).Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum.FITOTERAPIA,165,105402. |
| MLA | Guo,Kai,et al."Secondary metabolites from the Mongolian medicine Lomatogonium carinthiacum".FITOTERAPIA 165(2023):105402. |
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| File Name/Size | DocType | Version | Access | License | ||
| 1-s2.0-S0367326X2200（1128KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Download | |
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